Foamy combinatorial anti-HIV vectors with MGMTP140K potently inhibit HIV-1 and SHIV replication and mediate selection in vivo. - Wikidata - awgldk - TriplyDB

Foamy combinatorial anti-HIV vectors with MGMTP140K potently inhibit HIV-1 and SHIV replication and mediate selection in vivo.

Foamy combinatorial anti-HIV vectors with MGMTP140K potently inhibit HIV-1 and SHIV replication and mediate selection in vivo.

http://www.wikidata.org/entity/Q35182775

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Stem-cell-based gene therapy for HIV infection Progress toward curing HIV infection with hematopoietic cell transplantation Bone Marrow Gene Therapy for HIV/AIDS Foamy virus vectors for HIV gene therapy Combinatorial RNA-based gene therapy for the treatment of HIV/AIDS Genetically modified hematopoietic stem cell transplantation for HIV-1-infected patients: can we achieve a cure?Gene therapy strategies for HIV/AIDS: preclinical modeling in humanized mice Lentivirus-mediated Gene Transfer in Hematopoietic Stem Cells Is Impaired in SHIV-infected, ART-treated Nonhuman Primates.Heterologous Prime-Boost HIV-1 Vaccination Regimens in Pre-Clinical and Clinical Trials Intravenous injection of a foamy virus vector to correct canine SCID-X1.Protection of stem cell-derived lymphocytes in a primate AIDS gene therapy model after in vivo selection.Computational models of HIV-1 resistance to gene therapy elucidate therapy design principles Stem cell selection in vivo using foamy vectors cures canine pyruvate kinase deficiency.Stem cell-based anti-HIV gene therapy.Ex vivo gene therapy for HIV-1 treatment.VISA--Vector Integration Site Analysis server: a web-based server to rapidly identify retroviral integration sites from next-generation sequencing.Foamy viral vector integration sites in SCID-repopulating cells after MGMTP140K-mediated in vivo selection Establishment of an immunodeficient alcohol mouse model to study the effects of alcohol on human cells in vivo.Large animal models for foamy virus vector gene therapy.Multilineage polyclonal engraftment of Cal-1 gene-modified cells and in vivo selection after SHIV infection in a nonhuman primate model of AIDS Positive selection of mC46-expressing CD4+ T cells and maintenance of virus specific immunity in a primate AIDS model.Humanized mouse models of HIV infection Effect of fetal bovine serum on foamy and lentiviral vector production.Retargeted Foamy Virus Vectors Integrate Less Frequently Near Proto-oncogenes.Efficiency and safety of O⁶-methylguanine DNA methyltransferase (MGMT(P140K))-mediated in vivo selection in a humanized mouse model The majority of CD4+ T-cell depletion during acute simian-human immunodeficiency virus SHIV89.6P infection occurs in uninfected cells.Multifaceted roles of alkyltransferase and related proteins in DNA repair, DNA damage, resistance to chemotherapy, and research tools.Creating genetic resistance to HIV.Practical considerations in gene therapy for HIV cure.Strategies to Block HIV Transcription: Focus on Small Molecule Tat Inhibitors.Stem cell gene therapy for HIV: strategies to inhibit viral entry and replication.Evidence for the in vivo safety of insulated foamy viral vectors Recent advances in RNAi-based strategies for therapy and prevention of HIV-1/AIDS.Insulated Foamy Viral Vectors.Combinatorial hematopoietic stem cell transplantation and vaccination reduces viral pathogenesis following SHIV89.6P-challenge.Development of Third-generation Cocal Envelope Producer Cell Lines for Robust Lentiviral Gene Transfer into Hematopoietic Stem Cells and T-cells.A novel approach to block HIV-1 coreceptor CXCR4 in non-toxic manner.Cell and Gene Therapy for HIV Cure.Prospects for Foamy Viral Vector Anti-HIV Gene Therapy.Replacement of feline foamy virus bet by feline immunodeficiency virus vif yields replicative virus with novel vaccine candidate potential.

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P2860

Foamy combinatorial anti-HIV vectors with MGMTP140K potently inhibit HIV-1 and SHIV replication and mediate selection in vivo.

http://www.wikidata.org/entity/Q35182775

description

2009 nî lūn-bûn

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2009 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年论文

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Foamy combinatorial anti-HIV v ...... and mediate selection in vivo.

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Foamy combinatorial anti-HIV v ...... and mediate selection in vivo.

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D von Laer

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G D Trobridge

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G Sun

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H-P Kiem

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J J Rossi

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P2860

The failed HIV Merck vaccine study: a step back or a launching point for future vaccine development?

Human immunodeficiency virus type 1 coreceptors participate in postentry stages in the virus replication cycle and function in simian immunodeficiency virus infection

Resistance to HIV-1 infection in caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene

Homozygous defect in HIV-1 coreceptor accounts for resistance of some multiply-exposed individuals to HIV-1 infection

A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine

Isolation of human O6-alkylguanine-DNA alkyltransferase mutants highly resistant to inactivation by O6-benzylguanine.

A cell line-based neutralization assay for primary human immunodeficiency virus type 1 isolates that use either the CCR5 or the CXCR4 coreceptor.

The role of nonhuman primates in the development of an AIDS vaccine.

Exploiting internal ribosome entry sites in gene therapy vector design.

Transduction of human NOD/SCID-repopulating cells with both lymphoid and myeloid potential by foamy virus vectors.

P2888

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10.1038/GT.2009.118

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1

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26800058

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19741733

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3162371

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