Population pharmacokinetic analysis of sorafenib in patients with solid tumours.
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Early sorafenib-induced toxicity is associated with drug exposure and UGTIA9 genetic polymorphism in patients with solid tumors: a preliminary studySorafenib dose escalation is not uniformly associated with blood pressure elevations in normotensive patients with advanced malignancies.Exposure-toxicity relationship of sorafenib in Japanese patients with renal cell carcinoma and hepatocellular carcinoma.Influence of OATP1B1 Function on the Disposition of Sorafenib-β-D-GlucuronideHepatocellular Shuttling and Recirculation of Sorafenib-Glucuronide Is Dependent on Abcc2, Abcc3, and Oatp1a/1b.Sorafenib in advanced melanoma: a critical role for pharmacokinetics?Population pharmacokinetic-pharmacodynamic-disease progression model for effects of anakinra in Lewis rats with collagen-induced arthritis.Contribution of OATP1B1 and OATP1B3 to the disposition of sorafenib and sorafenib-glucuronidePlasma protein binding of sorafenib, a multi kinase inhibitor: in vitro and in cancer patients.Translational predictive biomarker analysis of the phase 1b sorafenib and bevacizumab study expansion cohort.Methodological assessment of HCC literatureA pharmacokinetic/pharmacodynamic model of tumor lysis syndrome in chronic lymphocytic leukemia patients treated with flavopiridol.Clinical efficacy of targeted biologic agents as second-line therapy of advanced thyroid cancer.Bridging the Gap Between Sorafinib Efficacy and Effectiveness in Advanced Hepatocellular Carcinoma.Population pharmacokinetic analysis of axitinib in healthy volunteers.Patient-Level Adverse Event Patterns in a Single-Institution Study of the Multi-Kinase Inhibitor Sorafenib.Practical guidelines for therapeutic drug monitoring of anticancer tyrosine kinase inhibitors: focus on the pharmacokinetic targets.Exogenous albumin inhibits sorafenib-induced cytotoxicity in human cancer cell linesInhibition of sodium-independent and sodium-dependent nucleobase transport activities by tyrosine kinase inhibitors.PharmGKB summary: sorafenib pathways.Sorafenib-Induced Acute Pancreatitis: Case Report and Review of the Literature.Sorafenib metabolism, transport, and enterohepatic recycling: physiologically based modeling and simulation in mice.Population pharmacokinetics modeling and analysis of foretinib in adult patients with advanced solid tumors.Commentary on: "Influence of OATP1B1 Function on the Disposition of Sorafenib-β-D-Glucuronide".Physiologically based pharmacokinetic models for everolimus and sorafenib in mice.Clinical pharmacokinetics of tyrosine kinase inhibitors: focus on pyrimidines, pyridines and pyrroles.Pharmacokinetics of single-agent axitinib across multiple solid tumor types.Pharmacokinetic-Guided Dosing of New Oral Cancer Agents.Acetylsalicylic Acid Governs the Effect of Sorafenib in RAS- Mutant Cancers.Pharmacodynamic and Pharmacokinetic Markers For Anti-angiogenic Cancer Therapy: Implications for Dosing and Selection of Patients.Measurement of sorafenib plasma concentration by high-performance liquid chromatography in patients with advanced hepatocellular carcinoma: is it useful the application in clinical practice? A pilot study.Correlation between clinical response to sorafenib in hepatocellular carcinoma treatment and polymorphisms of P-glycoprotein (ABCB1) and of breast cancer resistance protein (ABCG2): monocentric study.Sorafenib Dose Recommendation in Acute Myeloid Leukemia Based on Exposure-FLT3 Relationship.Association of UDP-glucuronosyltransferase 1A9 polymorphisms with adverse reactions to catechol-O-methyltransferase inhibitors in Parkinson's disease patients.Molecular Dynamics Simulation of VEGFR2 with Sorafenib and Other Urea-Substituted Aryloxy Compounds
P2860
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P2860
Population pharmacokinetic analysis of sorafenib in patients with solid tumours.
description
2011 nî lūn-bûn
@nan
2011 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Population pharmacokinetic analysis of sorafenib in patients with solid tumours.
@ast
Population pharmacokinetic analysis of sorafenib in patients with solid tumours.
@en
type
label
Population pharmacokinetic analysis of sorafenib in patients with solid tumours.
@ast
Population pharmacokinetic analysis of sorafenib in patients with solid tumours.
@en
prefLabel
Population pharmacokinetic analysis of sorafenib in patients with solid tumours.
@ast
Population pharmacokinetic analysis of sorafenib in patients with solid tumours.
@en
P2093
P2860
P1476
Population pharmacokinetic analysis of sorafenib in patients with solid tumours
@en
P2093
Diane R Mould
Elise C Kohn
Erin R Gardner
Jürgen Venitz
Lokesh Jain
Robert Yarchoan
Shivaani Kummar
Sukyung Woo
William D Figg
William L Dahut
P2860
P304
P356
10.1111/J.1365-2125.2011.03963.X
P407
P577
2011-08-01T00:00:00Z