Gene dose-dependent control of hematopoiesis and hematologic tumor suppression by CBP
about
CBP Is a dosage-dependent regulator of nuclear factor-kappaB suppression by the estrogen receptorIndividual CREB-target genes dictate usage of distinct cAMP-responsive coactivation mechanismsTargeting of p300/CREB binding protein coactivators by simian virus 40 is mediated through p53Specific inhibition of CBP/beta-catenin interaction rescues defects in neuronal differentiation caused by a presenilin-1 mutation.Conditional knockout mice reveal distinct functions for the global transcriptional coactivators CBP and p300 in T-cell developmentHuman papillomavirus oncoprotein E6 inactivates the transcriptional coactivator human ADA3MAP kinase phosphorylation-dependent activation of Elk-1 leads to activation of the co-activator p300.Cloning and characterization of PIMT, a protein with a methyltransferase domain, which interacts with and enhances nuclear receptor coactivator PRIP functionMOZ-TIF2 inhibits transcription by nuclear receptors and p53 by impairment of CBP functionPPARgamma1 and LXRalpha face a new regulator of macrophage cholesterol homeostasis and inflammatory responsiveness, AEBP1Nitric oxide-induced nuclear GAPDH activates p300/CBP and mediates apoptosisEssential function of p300 acetyltransferase activity in heart, lung and small intestine formationInhibition of p300/CBP by early B-cell factorGlobal transcriptional coactivators CREB-binding protein and p300 are highly essential collectively but not individually in peripheral B cellsAcetyltransferases and tumour suppressionHistone acetylation: novel target for the treatment of acute lymphoblastic leukemiaDevelopment of anticancer agents targeting the Wnt/β-catenin signalingRevisiting the case for genetically engineered mouse models in human myelodysplastic syndrome researchProtein lysine acetylation by p300/CBPAn intrinsically disordered region of the acetyltransferase p300 with similarity to prion-like domains plays a role in aggregationFragment-Based Discovery of a Selective and Cell-Active Benzodiazepinone CBP/EP300 Bromodomain Inhibitor (CPI-637)Histone acetyltransferases and histone deacetylases in B- and T-cell development, physiology and malignancyp53 Acetylation: Regulation and ConsequencesThe Role of Histone Acetyltransferases in Normal and Malignant HematopoiesisGeneration of a Selective Small Molecule Inhibitor of the CBP/p300 Bromodomain for Leukemia TherapyGenetic interaction between mutations in c-Myb and the KIX domains of CBP and p300 affects multiple blood cell lineages and influences both gene activation and repressionMonocytic leukemia zinc finger protein is essential for the development of long-term reconstituting hematopoietic stem cellsDifferential role of p300 and CBP acetyltransferase during myogenesis: p300 acts upstream of MyoD and Myf5Inactivating mutations of acetyltransferase genes in B-cell lymphomaCREB binding protein is required for both short-term and long-term memory formation.A small molecule inhibitor of beta-catenin/CREB-binding protein transcription [corrected]Quantitative analysis of CBP- and P300-induced histone acetylations in vivo using native chromatin.TLX1/HOX11-induced hematopoietic differentiation blockade.p53 targets simian virus 40 large T antigen for acetylation by CBPThe F-box protein beta-TrCp1/Fbw1a interacts with p300 to enhance beta-catenin transcriptional activity.Acetylation of the human T-cell leukemia virus type 1 Tax oncoprotein by p300 promotes activation of the NF-kappaB pathway.Transgenic mice expressing a truncated form of CREB-binding protein (CBP) exhibit deficits in hippocampal synaptic plasticity and memory storage.Purification and characterization of recombinant CH3 domain fragment of the CREB-binding protein.The HDAC inhibitor valproate induces a bivalent status of the CD20 promoter in CLL patients suggesting distinct epigenetic regulation of CD20 expression in CLL in vivo.Functional analysis of the p300 acetyltransferase domain: the PHD finger of p300 but not of CBP is dispensable for enzymatic activity
P2860
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P2860
Gene dose-dependent control of hematopoiesis and hematologic tumor suppression by CBP
description
2000 nî lūn-bûn
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2000 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի փետրվարին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Gene dose-dependent control of hematopoiesis and hematologic tumor suppression by CBP
@ast
Gene dose-dependent control of hematopoiesis and hematologic tumor suppression by CBP
@en
type
label
Gene dose-dependent control of hematopoiesis and hematologic tumor suppression by CBP
@ast
Gene dose-dependent control of hematopoiesis and hematologic tumor suppression by CBP
@en
prefLabel
Gene dose-dependent control of hematopoiesis and hematologic tumor suppression by CBP
@ast
Gene dose-dependent control of hematopoiesis and hematologic tumor suppression by CBP
@en
P2093
P2860
P1433
P1476
Gene dose-dependent control of hematopoiesis and hematologic tumor suppression by CBP
@en
P2093
D M Livingston
R T Bronson
P2860
P304
P577
2000-02-01T00:00:00Z