CTLA-4 dysregulation of self/tumor-reactive CD8+ T-cell function is CD4+ T-cell dependent. - Wikidata - awgldk - TriplyDB

CTLA-4 dysregulation of self/tumor-reactive CD8+ T-cell function is CD4+ T-cell dependent.

CTLA-4 dysregulation of self/tumor-reactive CD8+ T-cell function is CD4+ T-cell dependent.

http://www.wikidata.org/entity/Q35190928

about

Identification of the genomic insertion site of Pmel-1 TCR α and β transgenes by next-generation sequencing Mechanisms of spatial and temporal development of autoimmune vitiligo in tyrosinase-specific TCR transgenic mice.Cyclophosphamide induces bone marrow to yield higher numbers of precursor dendritic cells in vitro capable of functional antigen presentation to T cells in vivo.DC-HIL+ CD14+ HLA-DR no/low cells are a potential blood marker and therapeutic target for melanoma Differential CTLA-4 expression in human CD4+ versus CD8+ T cells is associated with increased NFAT1 and inhibition of CD4+ proliferation.Increased intensity lymphodepletion and adoptive immunotherapy--how far can we go?Mannan-modified adenovirus targeting TERT and VEGFR-2: A universal tumour vaccine.Inhibitory costimulation and anti-tumor immunity.Prognostic factors related to clinical response in patients with metastatic melanoma treated by CTL-associated antigen-4 blockade.Combination OX40 agonism/CTLA-4 blockade with HER2 vaccination reverses T-cell anergy and promotes survival in tumor-bearing mice.At the bench: preclinical rationale for CTLA-4 and PD-1 blockade as cancer immunotherapy Dendritic cell vaccination combined with CTLA4 blockade in patients with metastatic melanoma.Modulation of CTLA-4 and GITR for cancer immunotherapy.Immune regulatory antibodies: are they the next advance?Vitiligo, reactive oxygen species and T-cells.Modulation of tumor immunity by soluble and membrane-bound molecules at the immunological synapse.New approaches for the immunotherapy of acute myeloid leukemia.Negative immune checkpoints on T lymphocytes and their relevance to cancer immunotherapy.Phenotypic switch of CD8(+) T cells reactivated under hypoxia toward IL-10 secreting, poorly proliferative effector cells.Combined targeting of costimulatory (OX40) and coinhibitory (CTLA-4) pathways elicits potent effector T cells capable of driving robust antitumor immunity.Immunometabolic Regulations Mediated by Coinhibitory Receptors and Their Impact on T Cell Immune Responses.Immune and molecular correlates in melanoma treated with immune checkpoint blockade.Vitiligo: Focus on Clinical Aspects, Immunopathogenesis, and Therapy.

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P2860

CTLA-4 dysregulation of self/tumor-reactive CD8+ T-cell function is CD4+ T-cell dependent.

http://www.wikidata.org/entity/Q35190928

description

2006 nî lūn-bûn

@nan

2006 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2006 թվականի օգոստոսին հրատարակված գիտական հոդված

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2006年の論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年论文

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name

CTLA-4 dysregulation of self/t ...... tion is CD4+ T-cell dependent.

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CTLA-4 dysregulation of self/t ...... tion is CD4+ T-cell dependent.

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CTLA-4 dysregulation of self/t ...... tion is CD4+ T-cell dependent.

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CTLA-4 dysregulation of self/t ...... tion is CD4+ T-cell dependent.

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CTLA-4 dysregulation of self/t ...... tion is CD4+ T-cell dependent.

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BLOOD-2006-07-034066

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P1476

CTLA-4 dysregulation of self/tumor-reactive CD8+ T-cell function is CD4+ T-cell dependent

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P2093

Anju Ranganathan

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David M Heimann

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Deborah R Surman

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Luca Gattinoni

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Marc R Theoret

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Paul A Antony

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Steven A Rosenberg

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P2860

CD28/B7 system of T cell costimulation

Removal of homeostatic cytokine sinks by lymphodepletion enhances the efficacy of adoptively transferred tumor-specific CD8+ T cells

CD8+ T cell immunity against a tumor/self-antigen is augmented by CD4+ T helper cells and hindered by naturally occurring T regulatory cells.

Adoptive immunotherapy for cancer: building on success

IL-15 enhances the in vivo antitumor activity of tumor-reactive CD8+ T cells

CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation

Cancer regression and autoimmunity induced by cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma

B7/CD28 costimulation is essential for the homeostasis of the CD4+CD25+ immunoregulatory T cells that control autoimmune diabetes

Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease

CTLA-4 can function as a negative regulator of T cell activation

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3818-3823

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scholarly article

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10.1182/BLOOD-2006-07-034066

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12

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Nicholas P. Restifo

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6903477

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16882704

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1679662

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