Phagocytosis-dependent activation of a TLR9-BTK-calcineurin-NFAT pathway co-ordinates innate immunity to Aspergillus fumigatus. - Wikidata - awgldk - TriplyDB

Phagocytosis-dependent activation of a TLR9-BTK-calcineurin-NFAT pathway co-ordinates innate immunity to Aspergillus fumigatus.

Phagocytosis-dependent activation of a TLR9-BTK-calcineurin-NFAT pathway co-ordinates innate immunity to Aspergillus fumigatus.

http://www.wikidata.org/entity/Q35192436

about

Cryptococcus neoformans Intracellular Proliferation and Capsule Size Determines Early Macrophage Control of Infection.Paving the way for predictive diagnostics and personalized treatment of invasive aspergillosis Characterization of Aspergillus fumigatus Isolates from Air and Surfaces of the International Space Station Dectin-1 Controls TLR9 Trafficking to Phagosomes Containing β-1,3 Glucan Calcineurin Orchestrates Lateral Transfer of Aspergillus fumigatus during Macrophage Cell Death Rodent Models of Invasive Aspergillosis due to Aspergillus fumigatus: Still a Long Path toward Standardization.Immunity against fungi.Ca2+ Signaling but Not Store-Operated Ca2+ Entry Is Required for the Function of Macrophages and Dendritic Cells CD103+ Conventional Dendritic Cells Are Critical for TLR7/9-Dependent Host Defense against Histoplasma capsulatum, an Endemic Fungal Pathogen of Humans.A zebrafish larval model reveals early tissue-specific innate immune responses to Mucor circinelloides.Optimized Near-IR Fluorescent Agents for in Vivo Imaging of Btk Expression.NFAT1 transcription factor regulates cell cycle progression and cyclin E expression in B lymphocytes Calcineurin-NFAT signalling in myeloid leucocytes: new prospects and pitfalls in immunosuppressive therapy.Toll-like receptor 2-mediated MAPKs and NF-κB activation requires the GNAO1-dependent pathway in human mast cells.LC3-associated phagocytosis: a crucial mechanism for antifungal host defence against Aspergillus fumigatus.New advances in invasive aspergillosis immunobiology leading the way towards personalized therapeutic approaches.Endosomal sensing of fungi: current understanding and emerging concepts.Aspergillosis and stem cell transplantation: An overview of experimental pathogenesis studies.Nebulised amphotericin B-polymethacrylic acid nanoparticle prophylaxis prevents invasive aspergillosis.Treatment of Cyclosporin A retains host defense against invasive pulmonary aspergillosis in a non-immunosuppressive murine model by preserving the myeloid cell population.Inhibition of B Cell Receptor Signaling by Ibrutinib in Primary CNS Lymphoma.Fungal infections in patients treated with ibrutinib: two unusual cases of invasive aspergillosis and cryptococcal meningoencephalitis.Invasive aspergillosis related to ibrutinib therapy for chronic lymphocytic leukemia.Defective calcineurin/NFAT signaling in myeloid cells and susceptibility to aspergillosis in post-transplant patients.Impaired calcineurin signaling in myeloid cells results in downregulation of pentraxin-3 and increased susceptibility to aspergillosis.Bruton's Tyrosine Kinase: An Emerging Key Player in Innate Immunity.Macrophage-Microbe Interactions: Lessons from the Zebrafish Model.Host-Derived Leukotriene B4 Is Critical for Resistance against Invasive Pulmonary Aspergillosis.From phagocytosis to metaforosis: Calcineurin's deadly role in innate processing of fungi.Call for Action: Invasive Fungal Infections Associated With Ibrutinib and Other Small Molecule Kinase Inhibitors Targeting Immune Signaling Pathways.Host response to pulmonary fungal infections: A highlight on cell-driven immunity to Cryptococcus species and Aspergillus fumigatus.Inhibition of nuclear factor of activated T cells (NFAT) c3 activation attenuates acute lung injury and pulmonary edema in murine models of sepsis.Macrophages protect Talaromyces marneffei conidia from myeloperoxidase-dependent neutrophil fungicidal activity during infection establishment in vivo.Dendritic Cells in the Cross Hair for the Generation of Tailored Vaccines.Human NK Cells Develop an Exhaustion Phenotype During Polar Degranulation at the Hyphal Synapse Epigenetic Regulation of Autophagy: A Path to the Control of Autoimmunity Macrophages inhibit Aspergillus fumigatus germination and neutrophil-mediated fungal killing

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Phagocytosis-dependent activation of a TLR9-BTK-calcineurin-NFAT pathway co-ordinates innate immunity to Aspergillus fumigatus.

http://www.wikidata.org/entity/Q35192436

description

2015 nî lūn-bûn

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Phagocytosis-dependent activat ...... nity to Aspergillus fumigatus.

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Phagocytosis-dependent activat ...... nity to Aspergillus fumigatus.

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EMBO Molecular Medicine

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Phagocytosis-dependent activat ...... nity to Aspergillus fumigatus.

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Anand Shah

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Anna Reed

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Barbara Jensen

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Darius Armstrong-James

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Mark A Birrell

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Shinobu Saijo

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Sunil Shaunak

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Vanessa Marzola

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P2860

A Toll-like receptor recognizes bacterial DNA

Toll-like receptor 9-dependent immune activation by unmethylated CpG motifs in Aspergillus fumigatus DNA

Aspergillus fumigatus triggers inflammatory responses by stage-specific beta-glucan display

Real-time whole-body visualization of Chikungunya Virus infection and host interferon response in zebrafish

The zebrafish as a new model for the in vivo study of Shigella flexneri interaction with phagocytes and bacterial autophagy

Card9 controls a non-TLR signalling pathway for innate anti-fungal immunity

Dynamic response diversity of NFAT isoforms in individual living cells

Bruton's Tyrosine Kinase (BTK) and Vav1 contribute to Dectin1-dependent phagocytosis of Candida albicans in macrophages

Intracellular MHC class II molecules promote TLR-triggered innate immune responses by maintaining activation of the kinase Btk

Calcineurin/NFAT signaling is required for neuregulin-regulated Schwann cell differentiation

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240-258

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10.15252/EMMM.201404556

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3

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7

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Maria J Mazon Moya

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2015-01-30T00:00:00Z

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271538417

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25637383

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Aspergillus fumigatus

Toll-like receptor

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4364943

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