The investigational Aurora kinase A inhibitor alisertib (MLN8237) induces cell cycle G2/M arrest, apoptosis, and autophagy via p38 MAPK and Akt/mTOR signaling pathways in human breast cancer cells
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Wip1 phosphatase: between p53 and MAPK kinases pathwaysMethyl Sartortuoate Inhibits Colon Cancer Cell Growth by Inducing Apoptosis and G2/M-Phase Arrest.Alisertib Induces Cell Cycle Arrest, Apoptosis, Autophagy and Suppresses EMT in HT29 and Caco-2 Cells.Thromboxane A2 Receptor Inhibition Suppresses Multiple Myeloma Cell Proliferation by Inducing p38/c-Jun N-terminal Kinase (JNK) Mitogen-activated Protein Kinase (MAPK)-mediated G2/M Progression Delay and Cell Apoptosis.The p38 MAPK inhibitor BIRB796 enhances the antitumor effects of VX680 in cervical cancer.SKF-96365 activates cytoprotective autophagy to delay apoptosis in colorectal cancer cells through inhibition of the calcium/CaMKIIγ/AKT-mediated pathway.Chemoprevention of intestinal tumorigenesis by the natural dietary flavonoid myricetin in APCMin/+ mice.Cucurbitacin B exerts anti-cancer activities in human multiple myeloma cells in vitro and in vivo by modulating multiple cellular pathways.The Aurora kinase A inhibitor TC-A2317 disrupts mitotic progression and inhibits cancer cell proliferation.Cyclin E overexpression as a biomarker for combination treatment strategies in inflammatory breast cancer.Alisertib induces G2/M arrest, apoptosis, and autophagy via PI3K/Akt/mTOR- and p38 MAPK-mediated pathways in human glioblastoma cellsThe Aurora kinase inhibitors in cancer research and therapy.A SILAC-based proteomics elicits the molecular interactome of alisertib (MLN8237) in human erythroleukemia K562 cells.A proteomics-based investigation on the anticancer activity of alisertib, an Aurora kinase A inhibitor, in hepatocellular carcinoma Hep3B cells.Jianpi Huayu Decoction Inhibits Proliferation in Human Colorectal Cancer Cells (SW480) by Inducing G0/G1-Phase Cell Cycle Arrest and Apoptosis.A small-molecule inhibitor targeting the AURKC-IκBα interaction decreases transformed growth of MDA-MB-231 breast cancer cells.Silencing Aurora A leads to re-sensitization of breast cancer cells to Taxol through downregulation of SRC-mediated ERK and mTOR pathways.Protein Kinase Targets in Breast Cancer.Low-dose paclitaxel downregulates MYC proto-oncogene bHLH transcription factor expression in colorectal carcinoma cells.Piperlongumine induces apoptosis and autophagy in leukemic cells through targeting the PI3K/Akt/mTOR and p38 signaling pathways.The Aurora-Kinase A Phe31-Ile polymorphism as possible predictor of response to treatment in head and neck squamous cell carcinoma.Aurora kinase and FGFR3 inhibition results in significant apoptosis in molecular subgroups of multiple myeloma
P2860
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P2860
The investigational Aurora kinase A inhibitor alisertib (MLN8237) induces cell cycle G2/M arrest, apoptosis, and autophagy via p38 MAPK and Akt/mTOR signaling pathways in human breast cancer cells
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2015 nî lūn-bûn
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2015 թուականի Մարտին հրատարակուած գիտական յօդուած
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2015 թվականի մարտին հրատարակված գիտական հոդված
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2015年の論文
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2015年学术文章
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2015年学术文章
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2015年学术文章
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2015年学术文章
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The investigational Aurora kin ...... s in human breast cancer cells
@ast
The investigational Aurora kin ...... s in human breast cancer cells
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type
label
The investigational Aurora kin ...... s in human breast cancer cells
@ast
The investigational Aurora kin ...... s in human breast cancer cells
@en
prefLabel
The investigational Aurora kin ...... s in human breast cancer cells
@ast
The investigational Aurora kin ...... s in human breast cancer cells
@en
P2093
P2860
P356
P1476
The investigational Aurora kin ...... s in human breast cancer cells
@en
P2093
Jia-Xuan Qiu
Jin-Ping Li
Qi-Lun Liu
Shu-Feng Zhou
Shu-Ting Pan
Tianxin Yang
Xiao-Wu Chen
Xueji Zhang
Yin-Xue Yang
P2860
P304
P356
10.2147/DDDT.S75378
P407
P577
2015-03-16T00:00:00Z