Molecular genetic analysis of the heterodimeric splicing factor U2AF: the RS domain on either the large or small Drosophila subunit is dispensable in vivo
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Interaction between subunits of heterodimeric splicing factor U2AF is essential in vivo.The role of U2AF35 and U2AF65 in enhancer-dependent splicingThe conserved RNA recognition motif 3 of U2 snRNA auxiliary factor (U2AF 65) is essential in vivo but dispensable for activity in vitrohnRNP H is a component of a splicing enhancer complex that activates a c-src alternative exon in neuronal cellsThe SRm160/300 splicing coactivator is required for exon-enhancer functionNucleocytoplasmic shuttling of heterodimeric splicing factor U2AFDeletion of the N-terminus of SF2/ASF permits RS-domain-independent pre-mRNA splicing.Analysis of mutant phenotypes and splicing defects demonstrates functional collaboration between the large and small subunits of the essential splicing factor U2AF in vivo.A systematic analysis of the factors that determine the strength of pre-mRNA splicing enhancers.Molecular genetic analysis of U2AF59 in Schizosaccharomyces pombe: differential sensitivity of introns to mutational inactivation.Combinatorial control of a neuron-specific exonSplicing factor SF1 from Drosophila and Caenorhabditis: presence of an N-terminal RS domain and requirement for viabilityRNA structure replaces the need for U2AF2 in splicing.RNA-protein interactions that regulate pre-mRNA splicing.The Drosophila U1-70K protein is required for viability, but its arginine-rich domain is dispensable.Transcriptional repression by the Caenorhabditis elegans germ-line protein PIE-1.Pre-mRNA splicing of IgM exons M1 and M2 is directed by a juxtaposed splicing enhancer and inhibitor.Genetic analysis of the SR protein ASF/SF2: interchangeability of RS domains and negative control of splicing.Pre-mRNA splicing in the absence of an SR protein RS domain.Drosophila melanogaster male somatic cells feminized solely by TraF can collaborate with female germ cells to make functional eggsAlternative splicing of U2AF1 reveals a shared repression mechanism for duplicated exons.The splicing factor U2AF small subunit is functionally conserved between fission yeast and humans.RNA binding activity of heterodimeric splicing factor U2AF: at least one RS domain is required for high-affinity binding.Evidence for substrate-specific requirement of the splicing factor U2AF(35) and for its function after polypyrimidine tract recognition by U2AF(65).Characterization of U2AF(6), a splicing factor related to U2AF(35).Identification of U2AF(35)-dependent exons by RNA-Seq reveals a link between 3' splice-site organization and activity of U2AF-related proteins.Similar but distinct effects of the tristetraprolin/TIS11 immediate-early proteins on cell survival.Regulation of horizontal gene transfer in Bacillus subtilis by activation of a conserved site-specific proteaseMolecular characterization and phylogeny of U2AF35 homologs in plants.Distinct factor requirements for exonic splicing enhancer function and binding of U2AF to the polypyrimidine tract.
P2860
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P2860
Molecular genetic analysis of the heterodimeric splicing factor U2AF: the RS domain on either the large or small Drosophila subunit is dispensable in vivo
description
1998 nî lūn-bûn
@nan
1998 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Molecular genetic analysis of ...... subunit is dispensable in vivo
@ast
Molecular genetic analysis of ...... subunit is dispensable in vivo
@en
type
label
Molecular genetic analysis of ...... subunit is dispensable in vivo
@ast
Molecular genetic analysis of ...... subunit is dispensable in vivo
@en
prefLabel
Molecular genetic analysis of ...... subunit is dispensable in vivo
@ast
Molecular genetic analysis of ...... subunit is dispensable in vivo
@en
P2093
P2860
P356
P1433
P1476
Molecular genetic analysis of ...... subunit is dispensable in vivo
@en
P2093
P2860
P304
P356
10.1101/GAD.12.7.1010
P577
1998-04-01T00:00:00Z