A Role for Sigma Receptors in Stimulant Self Administration and Addiction.
about
Behavioral, biological, and chemical perspectives on atypical agents targeting the dopamine transporterCocaine inhibits dopamine D2 receptor signaling via sigma-1-D2 receptor heteromersGlial modulators as potential treatments of psychostimulant abuseStimulants as specific inducers of dopamine-independent σ agonist self-administration in ratsBiological substrates of addiction.Sigma-1 receptor chaperones in neurodegenerative and psychiatric disordersPreclinical efficacy of N-substituted benztropine analogs as antagonists of methamphetamine self-administration in rats2-Substituted 3β-Aryltropane Cocaine Analogs Produce Atypical Effects without Inducing Inward-Facing Dopamine Transporter Conformations.Decreases in cocaine self-administration with dual inhibition of the dopamine transporter and σ receptors.Antagonism of sigma-1 receptors blocks compulsive-like eating.Novel C-1 substituted cocaine analogs unlike cocaine or benztropine.Cocaine occupancy of sigma1 receptors and dopamine transporters in miceSelf-administration of cocaine induces dopamine-independent self-administration of sigma agonists.A role for sigma receptors in stimulant self-administration and addiction.Role of endoplasmic reticulum (ER) stress in cocaine-induced microglial cell death.Sigma receptors [σRs]: biology in normal and diseased statesIdentification of the Sigma-2 Receptor: Distinct from the Progesterone Receptor Membrane Component 1 (PGRMC1).Role of the σRs for Development of MedicationsN-Phenylpropyl-N'-(3-methoxyphenethyl)piperazine (YZ-185) Attenuates the Conditioned-Rewarding Properties of Cocaine in MiceIdentification of Antagonists Selective for Sigma Receptor Subtypes that are Active In vivo.Sigma-1 receptor chaperones regulate the secretion of brain-derived neurotrophic factor.Pharmacological characterization of a dopamine transporter ligand that functions as a cocaine antagonist.Cocaine disrupts histamine H3 receptor modulation of dopamine D1 receptor signaling: σ1-D1-H3 receptor complexes as key targets for reducing cocaine's effects.Predicting the Abuse Liability of Entactogen-Class, New and Emerging Psychoactive Substances via Preclinical Models of Drug Self-administration.N-phenylpropyl-N'-substituted piperazines occupy sigma receptors and alter methamphetamine-induced hyperactivity in mice.Mechanisms of activation of nucleus accumbens neurons by cocaine via sigma-1 receptor-inositol 1,4,5-trisphosphate-transient receptor potential canonical channel pathways.A selective sigma-2 receptor ligand antagonizes cocaine-induced hyperlocomotion in mice.Methamphetamine Induces Dopamine Release in the Nucleus Accumbens Through a Sigma Receptor-Mediated Pathway.Fluorinated PET Tracers for Molecular Imaging of σ1 Receptors in the Central Nervous System.Sigma-1 Receptor and Neuronal Excitability.Design and Investigation of a [18F]-Labeled Benzamide Derivative as a High Affinity Dual Sigma Receptor Subtype Radioligand for Prostate Tumor Imaging.Neuropharmacology of compulsive eating.
P2860
Q26829749-C1B211AE-90D8-430E-8A51-2BD6E101A143Q27325489-1592CC1D-A883-4EC0-8CFC-59C4B46D314FQ28307030-D022F986-78C7-4E65-BEF4-FB58EBCA8398Q30546325-3D6130D6-54F8-4BD1-A935-9D392DE9C315Q33835356-EB284A75-6BF4-48AF-A69A-D181D962B09BQ33920251-331E88C3-F139-4AE2-A80A-4516AD658ABCQ34382759-89944A28-9CC4-43F1-A6BE-19F0619DCB4CQ34509115-75C7C04B-3A2A-4597-BC1D-C0CAA63E9383Q35429841-FF8AB495-AAC7-4517-9B36-AC976320793EQ36323590-6C8737C3-8FC3-4AA5-B320-2EE5E9CEA92FQ36335545-C8661C09-4EE2-4943-BAFA-CD70CE368E30Q36494168-02E7287F-384C-4E84-8E8C-455927A0560EQ36610032-2C73A230-4B05-497D-BC9D-2423C80D250DQ36655919-2167C8B4-5815-42A1-8115-9D874D9A7550Q36874615-D2A27C48-5629-4A15-8C2E-27F401960C75Q37000551-52733147-9001-480B-88D7-D201D4224A1CQ37058581-0D2E0D28-580A-4C53-B26A-9DE1B09AF233Q37077086-F6B7AC36-D071-4BD2-B103-DA3F129FDD71Q37191461-24D6FE47-A4C5-4499-9C15-4696E1D59937Q37217129-FABB310F-0B9B-4FC0-8107-6FE799D391C2Q37300447-F20F9756-6CB9-4458-96C7-ABE2C73D20BAQ37405350-BA4EB50D-6173-4EE0-8B8B-64C7E9AF956FQ37617361-ADA17A50-FF0B-4D06-BD46-84C4EB2E543FQ39026719-AD220CD5-3E02-4DD3-8B0D-1E711B281398Q39183300-E119D7BF-E006-41E2-B185-F7DB651DBD0BQ41539028-64CD4A9E-5214-412E-A0BC-4DDB81801DA5Q43450779-ED664689-F40C-4FAE-8E38-01613E876757Q46252209-8478B0D5-B11A-4F81-9306-47DFC6D405C3Q48258075-DECDC0EA-A1A8-48D2-B07A-10FBD08EAC2FQ48272022-4B012EC7-18FD-4B1C-8424-8F33EBBEA301Q48298113-A324F052-D754-48BD-9C62-98A606CEB4A7Q52315306-F63E6013-8CF6-483C-9B08-0136D02DB60E
P2860
A Role for Sigma Receptors in Stimulant Self Administration and Addiction.
description
2011 nî lūn-bûn
@nan
2011 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
A Role for Sigma Receptors in Stimulant Self Administration and Addiction.
@ast
A Role for Sigma Receptors in Stimulant Self Administration and Addiction.
@en
type
label
A Role for Sigma Receptors in Stimulant Self Administration and Addiction.
@ast
A Role for Sigma Receptors in Stimulant Self Administration and Addiction.
@en
prefLabel
A Role for Sigma Receptors in Stimulant Self Administration and Addiction.
@ast
A Role for Sigma Receptors in Stimulant Self Administration and Addiction.
@en
P2093
P2860
P356
P1433
P1476
A Role for Sigma Receptors in Stimulant Self Administration and Addiction
@en
P2093
Shang-Yi Tsai
Takato Hiranita
Teruo Hayashi
Theresa Kopajtic
Tsung-Ping Su
P2860
P304
P356
10.3390/PH4060880
P577
2011-01-01T00:00:00Z