The rotenone model of Parkinson's disease: genes, environment and mitochondria.
about
Progression of Parkinson's disease pathology is reproduced by intragastric administration of rotenone in miceDopamine-independent locomotor actions of amphetamines in a novel acute mouse model of Parkinson disease.Sulforaphane protects against rotenone-induced neurotoxicity in vivo: Involvement of the mTOR, Nrf2, and autophagy pathways.Protection by Neuroglobin Expression in Brain PathologiesBiology of Parkinson's disease: pathogenesis and pathophysiology of a multisystem neurodegenerative disorderZebrafish chemical screening reveals the impairment of dopaminergic neuronal survival by cardiac glycosidesEnvironmental toxins trigger PD-like progression via increased alpha-synuclein release from enteric neurons in miceRotenone and paraquat perturb dopamine metabolism: A computational analysis of pesticide toxicity.Strengths and limitations of genetic mouse models of Parkinson's disease.High-content image-based screening for small-molecule chaperone amplifiers in heat shock.Maternal inheritance and mitochondrial DNA variants in familial Parkinson's diseaseMitochondria targeted peptides protect against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity.Oral N-acetyl-cysteine attenuates loss of dopaminergic terminals in alpha-synuclein overexpressing miceThe MAP kinase Pmk1 and protein kinase A are required for rotenone resistance in the fission yeast, Schizosaccharomyces pombe.Pathogenesis of Parkinson disease--the gut-brain axis and environmental factors.Mutational analysis of DJ-1 in Drosophila implicates functional inactivation by oxidative damage and aging.Translocation and potential neurological effects of fine and ultrafine particles a critical update.Mitochondrial Dysfunction and α-Synuclein Synaptic Pathology in Parkinson's Disease: Who's on First?Toxin models of mitochondrial dysfunction in Parkinson's disease.Differential degradation of motor deficits during gradual dopamine depletion with 6-hydroxydopamine in mice.Aralar plays a significant role in maintaining the survival and mitochondrial membrane potential of BV2 microglia.Novel Radiolytic Rotenone Derivative, Rotenoisin B with Potent Anti-Carcinogenic Activity in Hepatic Cancer CellsNeuroprotective effect of nerolidol against neuroinflammation and oxidative stress induced by rotenone.Ogg1 null mice exhibit age-associated loss of the nigrostriatal pathway and increased sensitivity to MPTP.Neurosupportive Role of Vanillin, a Natural Phenolic Compound, on Rotenone Induced Neurotoxicity in SH-SY5Y Neuroblastoma CellsMitochondrial import and accumulation of alpha-synuclein impair complex I in human dopaminergic neuronal cultures and Parkinson disease brain.The mitochondrial permeability transition in neurologic diseaseS-nitrosylation of XIAP compromises neuronal survival in Parkinson's diseaseA new method for quantifying mitochondrial axonal transport.Nigral degeneration with inclusion body formation and behavioral changes in rats after proteasomal inhibition.Synaptic protein alterations in Parkinson's disease.Rifampicin and Parkinson's disease.Agrochemicals, α-synuclein, and Parkinson's disease.Measurement of reactive oxygen species in the culture media using Acridan Lumigen PS-3 assay.PDGF-BB protects mitochondria from rotenone in T98G cells.DJ-1 deficiency triggers microglia sensitivity to dopamine toward a pro-inflammatory phenotype that is attenuated by rasagiline.Celastrol from 'Thunder God Vine' protects SH-SY5Y cells through the preservation of mitochondrial function and inhibition of p38 MAPK in a rotenone model of Parkinson's disease.Protective effects of zonisamide against rotenone-induced neurotoxicity.Mitochondrial complex I inhibitors, acetogenins, induce HepG2 cell death through the induction of the complete apoptotic mitochondrial pathway.Parkinson's disease: genetics and beyond.
P2860
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P2860
The rotenone model of Parkinson's disease: genes, environment and mitochondria.
description
2003 nî lūn-bûn
@nan
2003 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
The rotenone model of Parkinson's disease: genes, environment and mitochondria.
@ast
The rotenone model of Parkinson's disease: genes, environment and mitochondria.
@en
type
label
The rotenone model of Parkinson's disease: genes, environment and mitochondria.
@ast
The rotenone model of Parkinson's disease: genes, environment and mitochondria.
@en
prefLabel
The rotenone model of Parkinson's disease: genes, environment and mitochondria.
@ast
The rotenone model of Parkinson's disease: genes, environment and mitochondria.
@en
P2093
P1476
The rotenone model of Parkinson's disease: genes, environment and mitochondria.
@en
P2093
J Timothy Greenamyre
Ranjita Betarbet
Todd B Sherer
P304
P356
10.1016/S1353-8020(03)00023-3
P478
P577
2003-08-01T00:00:00Z