The distinctive roles of erythroid specific activator GATA-1 and NF-E2 in transcription of the human fetal γ-globin genes.
about
Regulation and function of the NFE2 transcription factor in hematopoietic and non-hematopoietic cellsSystematic mapping of functional enhancer-promoter connections with CRISPR interference.Chromatin loop formation in the β-globin locus and its role in globin gene transcriptionEditing the genome to introduce a beneficial naturally occurring mutation associated with increased fetal globin.Shift in GATA3 functions, and GATA3 mutations, control progression and clinical presentation in breast cancer.Chromatin looping and eRNA transcription precede the transcriptional activation of gene in the β-globin locus.A tissue-specific chromatin loop activates the erythroid ankyrin-1 promoterLdb1 regulates carbonic anhydrase 1 during erythroid differentiation.The transcription factor, Nuclear factor, erythroid 2 (Nfe2), is a regulator of the oxidative stress response during Danio rerio development.The hematopoietic regulator TAL1 is required for chromatin looping between the β-globin LCR and human γ-globin genes to activate transcription.Involvement of miRNA in erythroid differentiation.Discovery and validation of information theory-based transcription factor and cofactor binding site motifs.Exploring the mechanisms of genome-wide long-range interactions: interpreting chromosome organization.Hypoxia enhances the expression of prostate-specific antigen by modifying the quantity and catalytic activity of Jumonji C domain-containing histone demethylases.HIF-1-dependent induction of Jumonji domain-containing protein (JMJD) 3 under hypoxic conditions.Homozygosity for a haplotype in the HBG2-OR51B4 region is exclusive to Arab-Indian haplotype sickle cell anemia.HSP70 sequestration by free α-globin promotes ineffective erythropoiesis in β-thalassaemia.Deletion of transcription factor binding motifs using the CRISPR/spCas9 system in the β-globin LCR.Interferon-γ suppresses activin A/NF-E2 induction of erythroid gene expression through the NF-κB/c-Jun pathway.The effect of histone deacetylase inhibitors on AHSP expression.The intrinsic genetic and epigenetic regulator factors as therapeutic targets, and the effect on fetal globin gene expression.Single-cell transcriptomics reveals a new dynamical function of transcription factors during embryonic hematopoiesis.
P2860
Q29037128-44966244-D11E-4671-A89C-C3EFC2E5BC83Q33709312-0D6CA5E5-AD6C-4BC5-B651-C7208041B01DQ34276131-AD9E49A3-D3FD-48D2-9516-7CEBC63677D2Q34476277-F37332D7-C720-436F-BA66-C0D7841A6E3DQ35000662-22B3D109-7167-4F66-86E7-7BD8D2752A37Q35207245-614F7631-6A5C-4ADB-AE28-7BB1508530BFQ36352558-E0C13140-DA69-4C8A-A444-6B7562D557FDQ37038920-475906B7-35D3-44C1-AEA3-E85956A823C3Q37611347-E24A8987-7800-4F8F-A179-B0BE135FDF5DQ37701280-E16E686A-CF02-4F08-A74B-1A648EB9E088Q37983889-1112735F-5F4E-4CDE-8F6C-D6A26B1A497AQ38289980-48F084B1-82CC-404B-9D83-68C85C213F5EQ38697271-32B06E3E-6A7A-43A7-A929-3754DC744686Q39120599-9E29BF3B-9D05-4925-9661-1795D88EDD16Q41900444-DE7BCED1-10BD-4654-B545-EC700FFD0370Q41959356-E2C7F24C-43C7-4BB7-A7F9-10862D5C043CQ42152354-CA9D5CB8-BBA2-4B46-B13B-92135EA8E2E3Q42373773-401121C3-C09D-48F8-B64E-0AA2B525C09AQ43878488-102D6D5C-D0F9-4E57-9562-F17B74810F36Q48123934-5A55DABA-7B65-4367-83B5-0AB873EBDD7EQ49919974-4F03D319-0EEF-44BB-9B42-391696202439Q52350169-7BC71974-6E8D-4F50-80EE-9888934A48AF
P2860
The distinctive roles of erythroid specific activator GATA-1 and NF-E2 in transcription of the human fetal γ-globin genes.
description
2011 nî lūn-bûn
@nan
2011 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
The distinctive roles of eryth ...... he human fetal γ-globin genes.
@ast
The distinctive roles of eryth ...... he human fetal γ-globin genes.
@en
type
label
The distinctive roles of eryth ...... he human fetal γ-globin genes.
@ast
The distinctive roles of eryth ...... he human fetal γ-globin genes.
@en
prefLabel
The distinctive roles of eryth ...... he human fetal γ-globin genes.
@ast
The distinctive roles of eryth ...... he human fetal γ-globin genes.
@en
P2093
P2860
P356
P1476
The distinctive roles of eryth ...... he human fetal γ-globin genes.
@en
P2093
Chul Geun Kim
Seoyeon Kim
Yea Woon Kim
P2860
P304
P356
10.1093/NAR/GKR253
P407
P577
2011-05-24T00:00:00Z