Protein interactome reveals converging molecular pathways among autism disorders. - Wikidata - awgldk - TriplyDB

Protein interactome reveals converging molecular pathways among autism disorders.

Protein interactome reveals converging molecular pathways among autism disorders.

http://www.wikidata.org/entity/Q35203610

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Cellular and synaptic network defects in autism Two knockdown models of the autism genes SYNGAP1 and SHANK3 in zebrafish produce similar behavioral phenotypes associated with embryonic disruptions of brain morphogenesis.Actinin-4 Governs Dendritic Spine Dynamics and Promotes Their Remodeling by Metabotropic Glutamate Receptors.Hyperactive mTOR signals in the proopiomelanocortin-expressing hippocampal neurons cause age-dependent epilepsy and premature death in mice Neuroinflammation in Autism: Plausible Role of Maternal Inflammation, Dietary Omega 3, and Microbiota Phelan-McDermid syndrome: a review of the literature and practice parameters for medical assessment and monitoring 22q13.2q13.32 genomic regions associated with severity of speech delay, developmental delay, and physical features in Phelan-McDermid syndrome Ataxin1L is a regulator of HSC function highlighting the utility of cross-tissue comparisons for gene discovery Functional characterization of rare FOXP2 variants in neurodevelopmental disorder.The language-related transcription factor FOXP2 is post-translationally modified with small ubiquitin-like modifiers Protein interaction networks reveal novel autism risk genes within GWAS statistical noise Sporadic autism exomes reveal a highly interconnected protein network of de novo mutations Fusion of large-scale genomic knowledge and frequency data computationally prioritizes variants in epilepsy Phelan-McDermid Syndrome and SHANK3: Implications for Treatment.Fragile X Proteins FMRP and FXR2P Control Synaptic GluA1 Expression and Neuronal Maturation via Distinct Mechanisms.SHANK3 overexpression causes manic-like behaviour with unique pharmacogenetic properties.Investigating mechanisms underlying neurodevelopmental phenotypes of autistic and intellectual disability disorders: a perspective.Disruption of Arp2/3 results in asymmetric structural plasticity of dendritic spines and progressive synaptic and behavioral abnormalities Identifying diagnostically-relevant resting state brain functional connectivity in the ventral posterior complex via genetic data mining in autism spectrum disorder.The autism puzzle: challenging a mechanistic model on conceptual and historical grounds.Integrative Analysis of Brain Region-specific Shank3 Interactomes for Understanding the Heterogeneity of Neuronal Pathophysiology Related to SHANK3 Mutations.Testicular sex cord-stromal tumor in a boy with 2q37 deletion syndrome.The impact of the metabotropic glutamate receptor and other gene family interaction networks on autism.Striatal Transcriptome and Interactome Analysis of Shank3-overexpressing Mice Reveals the Connectivity between Shank3 and mTORC1 Signaling.Bio-collections in autism research.Expression profiling of autism candidate genes during human brain development implicates central immune signaling pathways.Networks of neuronal genes affected by common and rare variants in autism spectrum disorders.Transcriptomic analysis of genetically defined autism candidate genes reveals common mechanisms of action A stable pattern of EEG spectral coherence distinguishes children with autism from neuro-typical controls - a large case control study Patient-controlled encrypted genomic data: an approach to advance clinical genomics.Comparative RNA editing in autistic and neurotypical cerebella.Brain transcriptional and epigenetic associations with autism.De novo TBR1 mutations in sporadic autism disrupt protein functions.Increasing our understanding of human cognition through the study of Fragile X Syndrome.A pilot controlled trial of insulin-like growth factor-1 in children with Phelan-McDermid syndrome Epigenetic remodelling and dysregulation of DLGAP4 is linked with early-onset cerebellar ataxia Next-generation treatments for mental disorders.Molecular network analysis enhances understanding of the biology of mental disorders.The discovery of integrated gene networks for autism and related disorders.SANTA: quantifying the functional content of molecular networks.

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P2860

Protein interactome reveals converging molecular pathways among autism disorders.

http://www.wikidata.org/entity/Q35203610

description

2011 nî lūn-bûn

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2011 թուականի Յունիսին հրատարակուած գիտական յօդուած

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2011 թվականի հունիսին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

Protein interactome reveals converging molecular pathways among autism disorders.

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Protein interactome reveals converging molecular pathways among autism disorders.

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type

label

Protein interactome reveals converging molecular pathways among autism disorders.

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Protein interactome reveals converging molecular pathways among autism disorders.

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Protein interactome reveals converging molecular pathways among autism disorders.

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Protein interactome reveals converging molecular pathways among autism disorders.

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Protein interactome reveals converging molecular pathways among autism disorders.

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Brian C Dawson

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David E Hill

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Diana V Dugas

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Zaina Al-Mohtaseb

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P2860

Haploinsufficiency of the autism-associated Shank3 gene leads to deficits in synaptic function, social interaction, and social communication

Towards a proteome-scale map of the human protein–protein interaction network

Shank, a novel family of postsynaptic density proteins that binds to the NMDA receptor/PSD-95/GKAP complex and cortactin

Advances in autism genetics: on the threshold of a new neurobiology

Autism: highly heritable but not inherited

Neuroligins and neurexins link synaptic function to cognitive disease

The Autistic Neuron: Troubled Translation?

Autism: many genes, common pathways?

Autism and brain development

Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2

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