Epidermal growth factor receptor exposed to cigarette smoke is aberrantly activated and undergoes perinuclear trafficking. - Wikidata - awgldk - TriplyDB

Epidermal growth factor receptor exposed to cigarette smoke is aberrantly activated and undergoes perinuclear trafficking.

Epidermal growth factor receptor exposed to cigarette smoke is aberrantly activated and undergoes perinuclear trafficking.

http://www.wikidata.org/entity/Q35207808

about

Airway epithelial epidermal growth factor receptor mediates hogbarn dust-induced cytokine release but not Ca2+ response Neutral sphingomyelinase 2 (nSMase2) is a phosphoprotein regulated by calcineurin (PP2B)At the crossroads: EGFR and PTHrP signaling in cancer-mediated diseases of bone The role of oxidative stress in the biological responses of lung epithelial cells to cigarette smoke NAD(P)H: quinone oxidoreductase 1 deficiency conjoint with marginal vitamin C deficiency causes cigarette smoke induced myelodysplastic syndromes.A highly efficient peptide substrate for EGFR activates the kinase by inducing aggregation p120-catenin modulates airway epithelial cell migration induced by cigarette smoke Cigarette smoke activates the proto-oncogene c-src to promote airway inflammation and lung tissue destruction.EGF receptor exposed to oxidative stress acquires abnormal phosphorylation and aberrant activated conformation that impairs canonical dimerization Lung injury and cancer: Mechanistic insights into ceramide and EGFR signaling under cigarette smoke.Proteasome inhibition augments cigarette smoke-induced GM-CSF expression in trophoblast cells via the epidermal growth factor receptor.Lung injury and lung cancer caused by cigarette smoke-induced oxidative stress: Molecular mechanisms and therapeutic opportunities involving the ceramide-generating machinery and epidermal growth factor receptor.Activation of oncogenic pathways in idiopathic pulmonary fibrosis.Nexus of signaling and endocytosis in oncogenesis driven by non-small cell lung cancer-associated epidermal growth factor receptor mutants.Molecular mechanisms of cigarette smoke-induced proliferation of lung cells and prevention by vitamin C.Lung cancer and lung injury: the dual role of ceramide Src mediates cigarette smoke-induced resistance to tyrosine kinase inhibitors in NSCLC cells Cigarette smoke induces aberrant EGF receptor activation that mediates lung cancer development and resistance to tyrosine kinase inhibitors.Src regulates cigarette smoke-induced ceramide generation via neutral sphingomyelinase 2 in the airway epithelium Oxidative stress induced lung cancer and COPD: opportunities for epigenetic therapy.Chronic Obstructive Pulmonary Disease Is Not Associated with KRAS Mutations in Non-Small Cell Lung Cancer Na,K-ATPase is a target of cigarette smoke and reduced expression predicts poor patient outcome of smokers with lung cancer Gefitinib, an EGFR Tyrosine Kinase inhibitor, Prevents Smoke-Mediated Ciliated Airway Epithelial Cell Loss and Promotes Their Recovery.Cigarette smoking impairs the response of EGFR-TKIs therapy in lung adenocarcinoma patients by promoting EGFR signaling and epithelial-mesenchymal transition Omics for prediction of environmental health effects: Blood leukocyte-based cross-omic profiling reliably predicts diseases associated with tobacco smoking Soft TCPTP Agonism-Novel Target to Rescue Airway Epithelial Integrity by Exogenous Spermidine Barrier function of airway tract epithelium Neutral sphingomyelinase 2 is activated by cigarette smoke to augment ceramide-induced apoptosis in lung cell death.The impact of smoking status on radiologic tumor progression patterns and response to epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitors in lung adenocarcinoma with activating EGFR mutations.The biologic effects of cigarette smoke on cancer cells.The Effect of Cigarette Smoke on the Translocator Protein (TSPO) in Cultured Lung Cancer Cells.Resveratrol prevents cigarette smoke-induced keratinocytes damage.Cigarette smoke-induced disruption of bronchial epithelial tight junctions is prevented by transforming growth factor-β.Cigarette smoke affects keratinocytes SRB1 expression and localization via H2O2 production and HNE protein adducts formation.Cigarette smoke affects ABCAl expression via liver X receptor nuclear translocation in human keratinocytes.Airway epithelial barrier dysfunction in the pathogenesis and prognosis of respiratory tract diseases in childhood and adulthood.Cigarette smoke induces epidermal growth factor receptor-dependent redistribution of apical MUC1 and junctional beta-catenin in polarized human airway epithelial cells Cigarette smoke disrupts the integrity of airway adherens junctions through the aberrant interaction of p120-catenin with the cytoplasmic tail of MUC1.Endocytosis and cancer.Differential requirement for MEK/ERK and SMAD signaling in PAI-1 and CTGF expression in response to microtubule disruption.

P2860

Q23919646-46EAFA2E-A2AD-4F9C-87C1-F6E230E6D4CD Q24634655-C97CE77F-0A4F-4689-8418-96DFFF2EA81F Q26866067-2B1E5DDF-641C-4A46-BDEC-E898AF2DD7DC Q28252074-F834A5F3-4779-4C30-80DB-F297D90A4675 Q33395692-B5389223-6372-4B9B-9582-0494B44111A6 Q33723892-96408CD9-6AA8-4E78-AFEC-1B17666DD30E Q33791598-784E39D0-E21C-46A2-A339-0F6B3A3C94FC Q33799673-C3984F6B-5613-4F41-A9FF-DAC155CBE55D Q33996985-90F983B3-4ABF-41D1-B945-AD12A1C3DD2B Q34104798-756D2C06-0CFB-4392-BFD5-7CA6A485EEE7 Q34389203-15A6425D-325F-478D-AF50-F4863D9030D3 Q34432733-13C12449-B213-4D82-941E-E22561BE1BBC Q34478556-AE58706A-CAAF-4AA9-B200-DAE64E58A836 Q34657670-75DCDC0A-C3FF-4DDC-87D2-9E2774942702 Q35104755-6092492B-35A7-4D13-A196-4BBE00B49E7B Q35207787-1308690F-B6CF-40B2-827F-9F7DF8D7989B Q35207876-F4C70FAF-9FD7-4462-9E58-072449817872 Q35207885-062D95F8-67C3-4B19-8793-A92F3790C6F7 Q35816405-CD555E21-E45C-4762-923F-AF5C998EAC3C Q35841917-66EECE74-DCCB-4C51-A6A7-550A2873A0B1 Q35967703-89FD94EE-EC07-44C3-9826-15E506203785 Q36045551-5FDBCA0C-12B4-4D9B-A2D8-0D5954E7E66F Q36105638-F2C6EC6C-7178-475D-A9EC-2329388BCA8F Q36309536-E17B59A5-768B-44DF-81D6-23F8001193B0 Q36536235-7DC2CC95-36B6-448D-874C-5DE733349801 Q36966252-F91F4989-6EC0-4F89-9779-783250DD9FFA Q37197947-DD6D482F-A02B-4EEA-A7EC-9441F4401857 Q37264695-3214C79C-BE97-481E-B7E5-62AF6AE2B0F3 Q37528193-CFB7A98C-FFA6-437C-92D1-0B6C61CFA873 Q38231890-FACAF57E-DB5E-4B36-85C0-B38E32184162 Q38875562-B027736A-3BEB-4315-9C07-AF639C4862E0 Q38969096-82C2CD36-E391-47E6-895A-4C31554DDE78 Q39041487-F28949CF-3347-4BE9-A93D-B9BCA07F3410 Q39374915-86377621-BFEF-4348-A8D2-54F7BE9F3560 Q39642552-05C7661A-6F14-4B88-88E4-E7B386BEFF9E Q40060160-72E4ECCC-B845-4620-A2E0-BA2309D179B9 Q42470542-6E7A4CBD-8CDE-4887-9E7B-A8D8EF4E8E5B Q42734887-906F2783-AA1D-48E6-B01A-36D3F9EF8924 Q42869980-2288ACC1-88A5-4F57-985D-FD0899EB7602 Q43149092-FCDAB301-5F52-4439-BE6B-B36B4483F36A

P2860

Epidermal growth factor receptor exposed to cigarette smoke is aberrantly activated and undergoes perinuclear trafficking.

http://www.wikidata.org/entity/Q35207808

description

2007 nî lūn-bûn

@nan

2007 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2007 թվականի հոտեմբերին հրատարակված գիտական հոդված

@hy

2007年の論文

@ja

2007年論文

@yue

2007年論文

@zh-hant

2007年論文

@zh-hk

2007年論文

@zh-mo

2007年論文

@zh-tw

2007年论文

@wuu

name

Epidermal growth factor recept ...... rgoes perinuclear trafficking.

@ast

Epidermal growth factor recept ...... rgoes perinuclear trafficking.

@en

type

label

Epidermal growth factor recept ...... rgoes perinuclear trafficking.

@ast

Epidermal growth factor recept ...... rgoes perinuclear trafficking.

@en

prefLabel

Epidermal growth factor recept ...... rgoes perinuclear trafficking.

@ast

Epidermal growth factor recept ...... rgoes perinuclear trafficking.

@en

P1433

Q35207808-B1AF29A7-5BAD-47D1-AA1E-309BE6B4CAC0

P1476

Q35207808-0FD4785F-C69D-4FDE-8B0C-E3B57E92EA35

P2093

Q35207808-18ADEBCA-CDF1-4BDE-96FD-2BE65184E5A6

Q35207808-4D58D511-5B88-4B19-880E-134AB50A90B1

Q35207808-57A2A166-4082-4F52-B3F5-4A093C1E37BF

Q35207808-B39F1E4A-387F-42B1-BD08-6821D42EFADF

P2860

Q35207808-00FE5442-D930-47A4-BE19-D8644F11EFA5

Q35207808-01BA73B1-E3BC-40CF-B8A0-105F7057FB61

Q35207808-0A16D032-FDCA-4A60-B72E-0913198EB12D

Q35207808-316437C7-B234-4105-8C16-73679D0DD35A

Q35207808-416B3435-5EBD-43A2-B640-02BBE123D392

Q35207808-4842AFA1-D22F-41D6-B693-A13303B4488C

Q35207808-586E5EB4-B6AD-43F5-ADA0-A6CB1FF2B784

Q35207808-7A29C3F0-D131-4F70-85AF-65D365F4CBC7

Q35207808-818FE5F2-BC30-4FBB-8C09-AD41F91C8164

Q35207808-939B50E4-E7F3-45BD-9044-3E5B203E90F9

P304

Q35207808-0F7A9777-B7AB-4155-8211-FC625A620F29

P31

Q35207808-66973924-9A41-486D-846D-930C159ED11A

P356

Q35207808-5B182EED-F217-40F2-962D-52600A6A52C2

P407

Q35207808-F09C470A-9348-4C67-9DCB-0BB3D0DD248A

P433

Q35207808-706264A1-F27A-44CE-A659-739F0A6D40BA

P478

Q35207808-A6CCCB6A-72C6-4E35-A6DE-936563490F8A

P577

Q35207808-9F8BF4E7-F43C-45F8-821F-9F29789AD75B

P5875

Q35207808-C59BF195-01E1-436F-BE7F-A9D95E94A97D

P698

Q35207808-FFAE242A-0E85-4BD7-8DBA-E1927FADFB5F

P932

Q35207808-B25ACE3C-8655-45E4-8BEF-D79587F847EE

P356

P1433

P1476

Epidermal growth factor recept ...... rgoes perinuclear trafficking.

@en

P2093

Aaron R Danielson

http://www.w3.org/2001/XMLSchema#string

Elaine M Khan

http://www.w3.org/2001/XMLSchema#string

Roni Lanir

http://www.w3.org/2001/XMLSchema#string

Tzipora Goldkorn

http://www.w3.org/2001/XMLSchema#string

P2860

An RBCC protein implicated in maintenance of steady-state neuregulin receptor levels

Differential regulation of EGF receptor internalization and degradation by multiubiquitination within the kinase domain

Ceramide-mediated apoptosis in lung epithelial cells is regulated by glutathione

The phosphatidylinositol 3-Kinase AKT pathway in human cancer

Ubiquitin ligase activity and tyrosine phosphorylation underlie suppression of growth factor signaling by c-Cbl/Sli-1

Growth factor receptor binding protein 2-mediated recruitment of the RING domain of Cbl to the epidermal growth factor receptor is essential and sufficient to support receptor endocytosis.

Cigarette smoke induces MUC5AC mucin overproduction via tumor necrosis factor-alpha-converting enzyme in human airway epithelial (NCI-H292) cells.

Epidermal growth factor receptor family in lung cancer and premalignancy.

Targeting the PI3K-Akt pathway in human cancer: rationale and promise.

Surviving cell death through epidermal growth factor (EGF) signal transduction pathways: implications for cancer therapy.

P304

910-917

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1096/FJ.06-7729COM

http://www.w3.org/2001/XMLSchema#string

P407

P433

3

http://www.w3.org/2001/XMLSchema#string

P478

22

http://www.w3.org/2001/XMLSchema#string

P577

2007-10-30T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

5875712

http://www.w3.org/2001/XMLSchema#string

P698

17971399

http://www.w3.org/2001/XMLSchema#string

P932

4370285

http://www.w3.org/2001/XMLSchema#string