about
Explaining oscillations and variability in the p53-Mdm2 systemExperimental and computational analysis of polyglutamine-mediated cytotoxicityTDP-43 Proteinopathy and ALS: Insights into Disease Mechanisms and Therapeutic Targets.Age-related changes in glutathione and glutathione-related enzymes in rat brainAging is not associated with proteasome impairment in UPS reporter mice.Early-age-related changes in proteostasis augment immunopathogenesis of sepsis and acute lung injury.Proteasome inhibition modulates kinase activation in neural cells: relevance to ubiquitination, ribosomes, and survival.Ubiquitin/proteasome pathway impairment in neurodegeneration: therapeutic implicationsGene expression in the hippocampus: regionally specific effects of aging and caloric restrictionEvaluating age-associated phenotypes in a mouse model of protein dyshomeostasis.Systemic autoimmunity in TAM triple knockout mice causes inflammatory brain damage and cell death.Hippocampal damage in mouse and human forms of systemic autoimmune disease.Aging perturbs 26S proteasome assembly in Drosophila melanogasterQuantitative connection between polyglutamine aggregation kinetics and neurodegenerative process in patients with Huntington's disease.Ageing and neuronal vulnerability.Gene expression atlas of the mouse central nervous system: impact and interactions of age, energy intake and genderFamilial prion protein mutants inhibit Hrd1-mediated retrotranslocation of misfolded proteins by depleting misfolded protein sensor BiP.Synaptic vesicle protein trafficking at the glutamate synapse.Absence of ubiquitinated inclusions in hypocretin neurons of patients with narcolepsy.Protection from cytosolic prion protein toxicity by modulation of protein translocation.Protein homeostasis, aging and Alzheimer's disease.Structural disorder and the loss of RNA homeostasis in aging and neurodegenerative disease.Selective vulnerability of neurons to acute toxicity after proteasome inhibitor treatment: implications for oxidative stress and insolubility of newly synthesized proteins.Modelling the molecular mechanisms of aging.Analyses of human-chimpanzee orthologous gene pairs to explore evolutionary hypotheses of agingGenetic evidence linking age-dependent attenuation of the 26S proteasome with the aging process.Protective effects of mutant ubiquitin in transgenic mice.
P2860
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P2860
description
2003 nî lūn-bûn
@nan
2003 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Ubiquitin, proteasomes, and the aging brain.
@ast
Ubiquitin, proteasomes, and the aging brain.
@en
type
label
Ubiquitin, proteasomes, and the aging brain.
@ast
Ubiquitin, proteasomes, and the aging brain.
@en
prefLabel
Ubiquitin, proteasomes, and the aging brain.
@ast
Ubiquitin, proteasomes, and the aging brain.
@en
P2093
P1476
Ubiquitin, proteasomes, and the aging brain.
@en
P2093
Douglas A Gray
John Woulfe
Maria Tsirigotis
P356
10.1126/SAGEKE.2003.34.RE6
P577
2003-08-27T00:00:00Z