H5N1 influenza virus pathogenesis in genetically diverse mice is mediated at the level of viral load.
about
Systems biology from virus to humansThe role of host genetics in susceptibility to influenza: a systematic reviewAn updated systematic review of the role of host genetics in susceptibility to influenzaAn Ultrasensitive Mechanism Regulates Influenza Virus-Induced InflammationModeling host genetic regulation of influenza pathogenesis in the collaborative crossContinuing challenges in influenza.H7N9 and other pathogenic avian influenza viruses elicit a three-pronged transcriptomic signature that is reminiscent of 1918 influenza virus and is associated with lethal outcome in miceMolecular determinants of influenza virus pathogenesis in mice.A novel genetic locus linked to pro-inflammatory cytokines after virulent H5N1 virus infection in mice.Residues in the PB2 and PA genes contribute to the pathogenicity of avian H7N3 influenza A virus in DBA/2 mice.Infection with seasonal influenza virus elicits CD4 T cells specific for genetically conserved epitopes that can be rapidly mobilized for protective immunity to pandemic H1N1 influenza virus.Immunization with live virus vaccine protects highly susceptible DBA/2J mice from lethal influenza A H1N1 infectionThe controversy over H5N1 transmissibility research: an opportunity to define a practical response to a global threatH5N1 pathogenesis studies in mammalian models.Construction of the influenza A virus infection-induced cell-specific inflammatory regulatory network based on mutual information and optimizationSystems-based approach to examine the cytokine responses in primary mouse lung macrophages infected with low pathogenic avian Influenza virus circulating in South East Asia.Distinct gene loci control the host response to influenza H1N1 virus infection in a time-dependent manner.RNAseq expression analysis of resistant and susceptible mice after influenza A virus infection identifies novel genes associated with virus replication and important for host resistance to infectionInto the eye of the cytokine storm.Influenza H3N2 infection of the collaborative cross founder strains reveals highly divergent host responses and identifies a unique phenotype in CAST/EiJ mice.Protection from Severe Influenza Virus Infections in Mice Carrying the Mx1 Influenza Virus Resistance Gene Strongly Depends on Genetic Background.Functional variants regulating LGALS1 (Galectin 1) expression affect human susceptibility to influenza A(H7N9).Permissive and restricted virus infection of murine embryonic stem cells.The PA-gene-mediated lethal dissemination and excessive innate immune response contribute to the high virulence of H5N1 avian influenza virus in miceThe pH of activation of the hemagglutinin protein regulates H5N1 influenza virus replication and pathogenesis in miceNovel Highly Pathogenic Avian A(H5N2) and A(H5N8) Influenza Viruses of Clade 2.3.4.4 from North America Have Limited Capacity for Replication and Transmission in Mammals.A systems analysis identifies a feedforward inflammatory circuit leading to lethal influenza infectionProtection of Chinese painted quails (Coturnix chinensis) against a highly pathogenic H5N1 avian influenza virus strain after vaccination.Moving H5N1 studies into the era of systems biology.Beyond network structure: How heterogeneous susceptibility modulates the spread of epidemics.Antiviral therapy: a perspectiveGenetic variation in chromosome Y regulates susceptibility to influenza A virus infection.Autophagy mediates avian influenza H5N1 pseudotyped particle-induced lung inflammation through NF-κB and p38 MAPK signaling pathways.Childhood tolerance of severe influenza: a mortality analysis in mice.Collective effect of personal behavior induced preventive measures and differential rate of transmission on spread of epidemics.Pilot screening study of targeted genetic polymorphisms for association with seasonal influenza hospital admission."Gnothi Seauton": Leveraging the Host Response to Improve Influenza Virus Vaccine Efficacy.Interferon induced protein 35 exacerbates H5N1 influenza disease through the expression of IL-12p40 homodimer.
P2860
Q26798272-A84E15A7-EB42-43A7-B40E-D1908DD41E00Q26999342-49B67546-97F0-4046-B0F1-AFFC43A12E37Q27007082-DD1A8891-50F2-4667-B50E-4A61F660F206Q27320092-9E21EDCF-362C-430E-88DA-2EEEF24F7D24Q27336134-B0DBD1DD-D8D5-4988-BFB9-EB8B129E4C0DQ30363190-29AE84D4-C79A-4762-A374-0377B44687C4Q30364306-75C817C5-7257-42D5-992D-2DF4D8C3D1B4Q30364868-80558AF9-D931-4DA7-B43A-9F397D7C43CDQ30368887-5C1C6C1B-A9AD-4CE0-AC1E-79887B227D96Q30387215-730EAE1B-B9D7-49D6-9366-5440B4EE8601Q30407851-AF2053AE-22F7-4FAD-A2D7-47AE76717C79Q30421448-254A1F77-4059-4C4E-8B0F-09EFAD42B895Q30426929-989D97A9-9C6B-4604-B808-60E59478A6FFQ30427806-2E0A23FE-7294-4F34-922E-B40BE0CA25DFQ33592810-0CA90148-7751-4FC2-85DA-4C94ABEA38A2Q33742558-47B9FFC0-90F8-42C9-A014-F9032FA4971CQ34385369-13D34327-434E-4242-8B5F-0A7F6C97E1B1Q35761436-9691DC91-54F0-4D77-84D1-92E8FA88F736Q35804633-9DFE4185-FCFF-4691-9076-5D27EA19DD9EQ35938048-B1DBBEDA-A6DF-4CEB-AD1C-7DB0C00CA782Q36080821-8B2EA0DC-8660-4A34-AFBC-A2761F488667Q36291478-DB5925CD-1DA0-4106-9ADA-54AA9F5A5C9CQ36523231-C62E2AD1-4AF7-429B-AAAF-232AC0B7EBC4Q36607136-CC8668A6-7867-49B1-B512-83D02187E131Q36759926-A994C40C-CF11-4D3E-BB9B-BC0674FB634CQ36973179-ECF6E064-679F-4D6E-AFAE-DFD08A123F0CQ37148404-DC30FB3D-382C-46A9-8EA3-6851FF8A463FQ37316060-B02E8BB4-78EA-46E0-BCFB-388713208AC5Q37325837-E37E39ED-A49C-4545-B034-847814D08C6BQ37722964-9A002966-3A48-4215-B578-8340EEFC1350Q38286716-34BF21DB-6544-45D5-95DE-5A6AF2781D5EQ38938686-60F6298B-58BD-4604-97A1-A27F519B5405Q39062263-3FF3F3BA-E8CC-45E8-B176-9D38CE0BC571Q40052545-53C24280-676B-46E5-B019-F4A0A2A05B93Q40312699-EB742237-F5D7-4BC3-9907-0C06E1BE5029Q47605953-91DD0C7D-6916-4E48-B765-0991E9A89623Q52381548-2179090F-3450-4D18-8B6B-A63BF280CC20Q55346145-31BE8531-6756-40D7-8416-37547D2E4041
P2860
H5N1 influenza virus pathogenesis in genetically diverse mice is mediated at the level of viral load.
description
2011 nî lūn-bûn
@nan
2011 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
H5N1 influenza virus pathogene ...... ed at the level of viral load.
@ast
H5N1 influenza virus pathogene ...... ed at the level of viral load.
@en
type
label
H5N1 influenza virus pathogene ...... ed at the level of viral load.
@ast
H5N1 influenza virus pathogene ...... ed at the level of viral load.
@en
prefLabel
H5N1 influenza virus pathogene ...... ed at the level of viral load.
@ast
H5N1 influenza virus pathogene ...... ed at the level of viral load.
@en
P2093
P2860
P356
P1433
P1476
H5N1 influenza virus pathogene ...... ed at the level of viral load.
@en
P2093
Adrianus C M Boon
David Finkelstein
Gary Peltz
Guochun Liao
John Allard
Klaus Klumpp
Ming Zheng
P2860
P356
10.1128/MBIO.00171-11
P577
2011-09-06T00:00:00Z