Plasmacytoid dendritic cells are recruited to the colorectum and contribute to immune activation during pathogenic SIV infection in rhesus macaques. - Wikidata - awgldk - TriplyDB

Plasmacytoid dendritic cells are recruited to the colorectum and contribute to immune activation during pathogenic SIV infection in rhesus macaques.

Plasmacytoid dendritic cells are recruited to the colorectum and contribute to immune activation during pathogenic SIV infection in rhesus macaques.

http://www.wikidata.org/entity/Q35212361

about

Innate immune responses and rapid control of inflammation in African green monkeys treated or not with interferon-alpha during primary SIVagm infection In vivo administration of a JAK3 inhibitor during acute SIV infection leads to significant increases in viral load during chronic infection Kinetics of myeloid dendritic cell trafficking and activation: impact on progressive, nonprogressive and controlled SIV infections Blocking TLR7- and TLR9-mediated IFN-α production by plasmacytoid dendritic cells does not diminish immune activation in early SIV infection Loss of a tyrosine-dependent trafficking motif in the simian immunodeficiency virus envelope cytoplasmic tail spares mucosal CD4 cells but does not prevent disease progression.Immunopathogenesis of simian immunodeficiency virus infection in nonhuman primates The role of dendritic cells in driving genital tract inflammation and HIV transmission risk: are there opportunities to intervene?Impact of short-term HAART initiated during the chronic stage or shortly post-exposure on SIV infection of male genital organs.Immune activation and HIV persistence: implications for curative approaches to HIV infection.Targeting α4β7 integrin reduces mucosal transmission of simian immunodeficiency virus and protects gut-associated lymphoid tissue from infection.HIV-associated chronic immune activation.Dendritic cells in progression and pathology of HIV infection.Relationships between IL-17(+) subsets, Tregs and pDCs that distinguish among SIV infected elite controllers, low, medium and high viral load rhesus macaques.Plasmacytoid dendritic cell dynamics tune interferon-alfa production in SIV-infected cynomolgus macaques.Plasmacytoid dendritic cells suppress HIV-1 replication but contribute to HIV-1 induced immunopathogenesis in humanized mice.Blocking type I interferon production: a new therapeutic option to reduce the HIV-1-induced immune activation Gut dendritic cell activation links an altered colonic microbiome to mucosal and systemic T-cell activation in untreated HIV-1 infection Plasmacytoid Dendritic Cell Infection and Sensing Capacity during Pathogenic and Nonpathogenic Simian Immunodeficiency Virus Infection.Gut-Associated Plasmacytoid Dendritic Cells Display an Immature Phenotype and Upregulated Granzyme B in Subjects with HIV/AIDS.Role of intestinal microbiota and metabolites on gut homeostasis and human diseases.Species-specific differences in the expression and regulation of α4β7 integrin in various nonhuman primates Microbial translocation, immune activation, and HIV disease.Virus-encoded TLR ligands reveal divergent functional responses of mononuclear phagocytes in pathogenic simian immunodeficiency virus infection.Myeloid dendritic cells isolated from tissues of SIV-infected Rhesus macaques promote the induction of regulatory T cells.E2-2, a novel immunohistochemical marker for both human and monkey plasmacytoid dendritic cells.Plasmacytoid dendritic cells in HIV infection.Simian immunodeficiency virus interactions with macaque dendritic cells.The frequency of α₄β₇(high) memory CD4⁺ T cells correlates with susceptibility to rectal simian immunodeficiency virus infection.Estimating the contribution of the gut to plasma viral load in early SIV infection Antigen-presenting cell candidates for HIV-1 transmission in human distal colonic mucosa defined by CD207 dendritic cells and CD209 macrophages.Dendritic cell dysregulation during HIV-1 infection.Identification of novel oligonucleotides from mitochondrial DNA that spontaneously induce plasmacytoid dendritic cell activation.Type I interferon: understanding its role in HIV pathogenesis and therapy.Persistent accumulation of gut macrophages with impaired phagocytic function correlates with SIV disease progression in macaques.The levels of DNGR-1 and its ligand-bearing cells were altered after human and simian immunodeficiency virus infection.Dendritic cell migration in health and disease.Transcriptomic meta-analysis identifies gene expression characteristics in various samples of HIV-infected patients with nonprogressive disease.Δ9-Tetrahydrocannabinol Suppresses Secretion of IFNα by Plasmacytoid Dendritic Cells From Healthy and HIV-Infected Individuals.Tim-3 is a Marker of Plasmacytoid Dendritic Cell Dysfunction during HIV Infection and Is Associated with the Recruitment of IRF7 and p85 into Lysosomes and with the Submembrane Displacement of TLR9.Macrophage accumulation in gut mucosa differentiates AIDS from chronic SIV infection in rhesus macaques.

P2860

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P2860

Plasmacytoid dendritic cells are recruited to the colorectum and contribute to immune activation during pathogenic SIV infection in rhesus macaques.

http://www.wikidata.org/entity/Q35212361

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2011 nî lūn-bûn

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2011 թուականի Յունիսին հրատարակուած գիտական յօդուած

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2011 թվականի հունիսին հրատարակված գիտական հոդված

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2011年の論文

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Plasmacytoid dendritic cells a ...... infection in rhesus macaques.

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Guido Silvestri

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Mariam Siddiqui

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Pragati Nigam

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Rama Rao Amara

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Ravi Dyavar Shetty

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Steven E Bosinger

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Suefen Kwa

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Sunil Kannanganat

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Wendy Armstrong

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P2860

Emerging concepts in the immunopathogenesis of AIDS

Transcriptional profiling in pathogenic and non-pathogenic SIV infections reveals significant distinctions in kinetics and tissue compartmentalization

IPC: professional type 1 interferon-producing cells and plasmacytoid dendritic cell precursors

Gastrointestinal tract as a major site of CD4+ T cell depletion and viral replication in SIV infection

Massive infection and loss of memory CD4+ T cells in multiple tissues during acute SIV infection

Preliminary in vivo efficacy studies of a recombinant rhesus anti-alpha(4)beta(7) monoclonal antibody.

Lack of mucosal immune reconstitution during prolonged treatment of acute and early HIV-1 infection.

HIV-induced type I interferon and tryptophan catabolism drive T cell dysfunction despite phenotypic activation

Sex differences in the Toll-like receptor-mediated response of plasmacytoid dendritic cells to HIV-1.

Cycling of gut mucosal CD4+ T cells decreases after prolonged anti-retroviral therapy and is associated with plasma LPS levels.

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2763-2773

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51238939

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