Nucleotides and phosphorylation bi-directionally modulate Ca2+/calmodulin-dependent protein kinase II (CaMKII) binding to the N-methyl-D-aspartate (NMDA) receptor subunit GluN2B.
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Dynamic Regulation of N-Methyl-d-aspartate (NMDA) and α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptors by Posttranslational ModificationsExcitotoxic insult results in a long-lasting activation of CaMKIIα and mitochondrial damage in living hippocampal neuronsProtection of α-CaMKII from Dephosphorylation by GluN2B Subunit of NMDA Receptor Is Abolished by Mutation of Glu96 or His282 of α-CaMKIIAutonomous CaMKII requires further stimulation by Ca2+/calmodulin for enhancing synaptic strengthEffect of multimeric structure of CaMKII in the GluN2B-mediated modulation of kinetic parameters of ATP.CaMKII isoforms differ in their specific requirements for regulation by nitric oxide.CaMKII binding to GluN2B is differentially affected by macromolecular crowding reagents.Catalytically Dead αCaMKII K42M Mutant Acts as a Dominant Negative in the Control of Synaptic Strength.Substrate-selective and calcium-independent activation of CaMKII by α-actinin.Live imaging of endogenous Ca²⁺/calmodulin-dependent protein kinase II in neurons reveals that ischemia-related aggregation does not require kinase activityCaMKII regulation in information processing and storage.Effects on polo-like kinase 1 polo-box domain binding affinities of peptides incurred by structural variation at the phosphoamino acid position.Coordination of Protein Phosphorylation and Dephosphorylation in Synaptic PlasticityThe CaMKII/NMDAR complex as a molecular memoryActivated CaMKII couples GluN2B and casein kinase 2 to control synaptic NMDA receptors.Persistent reversal of enhanced amphetamine intake by transient CaMKII inhibitionMultiple CaMKII Binding Modes to the Actin Cytoskeleton Revealed by Single-Molecule Imaging.Recombinant probes reveal dynamic localization of CaMKIIα within somata of cortical neurons.Enzymatic activity of CaMKII is not required for its interaction with the glutamate receptor subunit GluN2B.The prion protein regulates glutamate-mediated Ca2+ entry and mitochondrial Ca2+ accumulation in neurons.In vitro reconstitution of a CaMKII memory switch by an NMDA receptor-derived peptide.DAPK1 Mediates LTD by Making CaMKII/GluN2B Binding LTP Specific.CaMKII binding to GluN2B is important for massed spatial learning in the Morris water maze.Memory Erasure Experiments Indicate a Critical Role of CaMKII in Memory Storage.Biochemical principles underlying the stable maintenance of LTP by the CaMKII/NMDAR complex.The CaMKII/GluN2B Protein Interaction Maintains Synaptic Strength.Ca2+ /calmodulin-dependent protein kinase II in spinal dorsal horn contributes to the pain hypersensitivity induced by γ-aminobutyric acid type a receptor inhibition.CaMKII Requirement for in Vivo Insular Cortex LTP Maintenance and CTA Memory Persistence.CaMKII-mediated phosphorylation of GluN2B regulates recombinant NMDA receptor currents in a chloride-dependent manner.
P2860
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P2860
Nucleotides and phosphorylation bi-directionally modulate Ca2+/calmodulin-dependent protein kinase II (CaMKII) binding to the N-methyl-D-aspartate (NMDA) receptor subunit GluN2B.
description
2011 nî lūn-bûn
@nan
2011 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Nucleotides and phosphorylatio ...... NMDA) receptor subunit GluN2B.
@ast
Nucleotides and phosphorylatio ...... NMDA) receptor subunit GluN2B.
@en
type
label
Nucleotides and phosphorylatio ...... NMDA) receptor subunit GluN2B.
@ast
Nucleotides and phosphorylatio ...... NMDA) receptor subunit GluN2B.
@en
prefLabel
Nucleotides and phosphorylatio ...... NMDA) receptor subunit GluN2B.
@ast
Nucleotides and phosphorylatio ...... NMDA) receptor subunit GluN2B.
@en
P2093
P2860
P356
P1476
Nucleotides and phosphorylatio ...... NMDA) receptor subunit GluN2B.
@en
P2093
Heather O'Leary
Jacki M Rorabaugh
K Ulrich Bayer
Steven J Coultrap
Wallace H Liu
P2860
P304
31272-31281
P356
10.1074/JBC.M111.233668
P407
P577
2011-07-18T00:00:00Z