Human aging is characterized by focused changes in gene expression and deregulation of alternative splicing.
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Age-associated bidirectional modulation of gene expression in single identified R15 neuron of AplysiaCCAAT-enhancer-binding protein-beta expression in vivo is associated with muscle strengthSafety and efficacy of azacitidine in the treatment of elderly patients with myelodysplastic syndromeA systems biology approach to the effect of aging, immunosenescence and vaccine responseThe hallmarks of agingBiological Age Predictors.Gene transcripts associated with muscle strength: a CHARGE meta-analysis of 7,781 persons.Identification of a prognostic signature for old-age mortality by integrating genome-wide transcriptomic data with the conventional predictors: the Vitality 90+ Study.Identification of Potential Key lncRNAs and Genes Associated with Aging Based on Microarray Data of Adipocytes from Mice.Rheumatoid Arthritis, Immunosenescence and the Hallmarks of AgingTranscriptomic profiles of aging in naïve and memory CD4+ cells from miceIdentification of a T cell gene expression clock obtained by exploiting a MZ twin design.Comprehensive transcriptional landscape of aging mouse liver.Whole blood gene expression and interleukin-6 levels.Age-associated changes in basal NF-κB function in human CD4+ T lymphocytes via dysregulation of PI3 kinase.Transcriptional analysis reveals gender-specific changes in the aging of the human immune system.Meta-analysis on blood transcriptomic studies identifies consistently coexpressed protein-protein interaction modules as robust markers of human agingTranscriptomic profiles of aging in purified human immune cellsGene-expression signature functional annotation of breast cancer tumours in function of ageGenomics and successful aging: grounds for renewed optimism?Influence of ageing and essential amino acids on quantitative patterns of troponin T alternative splicing in human skeletal muscle.Decoding the Regulatory Landscape of Ageing in Musculoskeletal Engineered Tissues Using Genome-Wide DNA Methylation and RNASeq.Gene expression markers of age-related inflammation in two human cohorts.Towards a gene expression biomarker set for human biological age.The transcriptional landscape of age in human peripheral blood.Epigenomic Indicators of Age in African AmericansLife span extension by targeting a link between metabolism and histone acetylation in Drosophila.Global genome splicing analysis reveals an increased number of alternatively spliced genes with aging.Identifying the genomic determinants of aging and longevity in human population studies: progress and challenges.Older Age Results in Differential Gene Expression after Mild Traumatic Brain Injury and Is Linked to Imaging Differences at Acute Follow-up.Changes in the expression of splicing factor transcripts and variations in alternative splicing are associated with lifespan in mice and humans.CircRNA accumulation in the aging mouse brain.Sex- and age-interacting eQTLs in human complex diseases.MicroRNAs miR-203-3p, miR-664-3p and miR-708-5p are associated with median strain lifespan in mice.Advancing age is associated with gene expression changes resembling mTOR inhibition: evidence from two human populations.Reproductive aging: insights from model organisms.The Splicing Factor SRSF1 as a Marker for Endothelial Senescence.MicroRNAs as Mediators of the Ageing Process.Changes in splicing factor expression are associated with advancing age in man.Developing Peripheral Blood Gene Expression-Based Diagnostic Tests for Coronary Artery Disease: a Review.
P2860
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P2860
Human aging is characterized by focused changes in gene expression and deregulation of alternative splicing.
description
2011 nî lūn-bûn
@nan
2011 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Human aging is characterized b ...... ation of alternative splicing.
@ast
Human aging is characterized b ...... ation of alternative splicing.
@en
type
label
Human aging is characterized b ...... ation of alternative splicing.
@ast
Human aging is characterized b ...... ation of alternative splicing.
@en
prefLabel
Human aging is characterized b ...... ation of alternative splicing.
@ast
Human aging is characterized b ...... ation of alternative splicing.
@en
P2093
P2860
P50
P1433
P1476
Human aging is characterized b ...... ation of alternative splicing.
@en
P2093
Alice C Holly
Andrew R Wood
David Melzer
Dena Hernandez
Jack M Guralnik
Lorna W Harries
Rachel M Bradley-Smith
Timothy M Frayling
William Henley
P2860
P304
P356
10.1111/J.1474-9726.2011.00726.X
P577
2011-07-19T00:00:00Z