CD27 mediates interleukin-2-independent clonal expansion of the CD8+ T cell without effector differentiation.
about
Targeting the T-cell co-stimulatory CD27/CD70 pathway in cancer immunotherapy: rationale and potentialCD27 stimulation promotes the frequency of IL-7 receptor-expressing memory precursors and prevents IL-12-mediated loss of CD8(+) T cell memory in the absence of CD4(+) T cell help.CD27 sustains survival of CTLs in virus-infected nonlymphoid tissue in mice by inducing autocrine IL-2 production.CD27 is a thymic determinant of the balance between interferon-gamma- and interleukin 17-producing gammadelta T cell subsetsPredicting cytotoxic T-cell age from multivariate analysis of static and dynamic biomarkers.Opposing effects of CD70 costimulation during acute and chronic lymphocytic choriomeningitis virus infection of miceMHC class Ib-restricted CD8 T cells differ in dependence on CD4 T cell help and CD28 costimulation over the course of mouse polyomavirus infectionLoss of T cell receptor-induced Bmi-1 in the KLRG1(+) senescent CD8(+) T lymphocyte.Memory programming in CD8(+) T-cell differentiation is intrinsic and is not determined by CD4 help.A subset of dendritic cells induces CD4+ T cells to produce IFN-gamma by an IL-12-independent but CD70-dependent mechanism in vivo.Interlinking interleukin-7.Interactions between immunity, proliferation and molecular subtype in breast cancer prognosis.Uncoupling T-cell expansion from effector differentiation in cell-based immunotherapy.Generating diversity: transcriptional regulation of effector and memory CD8 T-cell differentiation.Role of CD27/CD70 pathway of activation in immunity and tolerance.Tumor-induced myeloid-derived suppressor cell subsets exert either inhibitory or stimulatory effects on distinct CD8+ T-cell activation events.Host-Derived CD70 Suppresses Murine Graft-versus-Host Disease by Limiting Donor T Cell Expansion and Effector Function.Advantage of tacrolimus/mycophenolate mofetil regimen for cytotoxic T cell-mediated defence and its inhibition by additive steroid administration in high-risk liver transplant recipients.T-bet-mediated differentiation of the activated CD8+ T cell.Late signals from CD27 prevent Fas-dependent apoptosis of primary CD8+ T cellsAntibody Tumor Targeting Is Enhanced by CD27 Agonists through Myeloid Recruitment.The Quantity of Autocrine IL-2 Governs the Expansion Potential of CD8+ T Cells.Early coupled up-regulation of interleukin-12 receptor beta-1 in CD8+ central memory and effector T cells for better clinical outcomes in liver transplant recipients.
P2860
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P2860
CD27 mediates interleukin-2-independent clonal expansion of the CD8+ T cell without effector differentiation.
description
2006 nî lūn-bûn
@nan
2006 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
CD27 mediates interleukin-2-in ...... hout effector differentiation.
@ast
CD27 mediates interleukin-2-in ...... hout effector differentiation.
@en
type
label
CD27 mediates interleukin-2-in ...... hout effector differentiation.
@ast
CD27 mediates interleukin-2-in ...... hout effector differentiation.
@en
prefLabel
CD27 mediates interleukin-2-in ...... hout effector differentiation.
@ast
CD27 mediates interleukin-2-in ...... hout effector differentiation.
@en
P2093
P2860
P50
P356
P1476
CD27 mediates interleukin-2-in ...... thout effector differentiation
@en
P2093
Aymen Al-Shamkhani
Douglas T Fearon
James M Carr
Marlene J Carrasco
Paul J Bambrough
P2860
P304
19454-19459
P356
10.1073/PNAS.0609706104
P407
P577
2006-12-11T00:00:00Z