Dysfunction of the CNS-heart axis in mouse models of Huntington's disease.
about
CRISPR/Cas9: a powerful genetic engineering tool for establishing large animal models of neurodegenerative diseasesDeveloping stem cell therapies for juvenile and adult-onset Huntington's diseaseHDAC4-myogenin axis as an important marker of HD-related skeletal muscle atrophyCLIP-GENE: a web service of the condition specific context-laid integrative analysis for gene prioritization in mouse TF knockout experiments.High-resolution respirometry of fine-needle muscle biopsies in pre-manifest Huntington's disease expansion mutation carriers shows normal mitochondrial respiratory function.The pathogenic exon 1 HTT protein is produced by incomplete splicing in Huntington's disease patientsNeurocardiovascular deficits in the Q175 mouse model of Huntington's disease.Early transcriptional alteration of histone deacetylases in a murine model of doxorubicin-induced cardiomyopathy.The Huntington's disease-related cardiomyopathy prevents a hypertrophic response in the R6/2 mouse model.Skeletal muscle pathology in Huntington's diseaseCardiac Dysfunction in the BACHD Mouse Model of Huntington's Disease.SIRT1 Activity Is Linked to Its Brain Region-Specific Phosphorylation and Is Impaired in Huntington's Disease Mice.Longitudinal in vivo MRI in a Huntington's disease mouse model: Global atrophy in the absence of white matter microstructural damage.Correlations of Behavioral Deficits with Brain Pathology Assessed through Longitudinal MRI and Histopathology in the HdhQ150/Q150 Mouse Model of Huntington's Disease.Non-Hsp genes are essential for HSF1-mediated maintenance of whole body homeostasis.Impaired Nitric Oxide Mediated Vasodilation In The Peripheral Circulation In The R6/2 Mouse Model Of Huntington's DiseaseFrequency of nuclear mutant huntingtin inclusion formation in neurons and glia is cell-type-specific.Transcriptional Signature of an Altered Purine Metabolism in the Skeletal Muscle of a Huntington's Disease Mouse ModelHDAC4 as a potential therapeutic target in neurodegenerative diseases: a summary of recent achievementsExogenous GDF11 induces cardiac and skeletal muscle dysfunction and wasting.Huntington's disease is a multi-system disorder.Motor phenotype is not associated with vascular dysfunction in symptomatic Huntington's disease transgenic R6/2 (160 CAG) miceHSF1-dependent and -independent regulation of the mammalian in vivo heat shock response and its impairment in Huntington's disease mouse models.A shared mechanism of muscle wasting in cancer and Huntington's disease.Allele-Specific Reduction of the Mutant Huntingtin Allele Using Transcription Activator-Like Effectors in Human Huntington's Disease Fibroblasts.Changes in cardiac nucleotide metabolism in Huntington's disease.Cardiac Fas-Dependent and Mitochondria-Dependent Apoptotic Pathways in a Transgenic Mouse Model of Huntington's Disease.Integrated genomics and proteomics define huntingtin CAG length-dependent networks in mice.Myostatin inhibition prevents skeletal muscle pathophysiology in Huntington's disease mice.Cardiac mTORC1 Dysregulation Impacts Stress Adaptation and Survival in Huntington's Disease.Neuro-Cardio Mechanisms in Huntington's Disease and Other Neurodegenerative Disorders.
P2860
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P2860
Dysfunction of the CNS-heart axis in mouse models of Huntington's disease.
description
2014 nî lūn-bûn
@nan
2014 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Dysfunction of the CNS-heart axis in mouse models of Huntington's disease.
@ast
Dysfunction of the CNS-heart axis in mouse models of Huntington's disease.
@en
type
label
Dysfunction of the CNS-heart axis in mouse models of Huntington's disease.
@ast
Dysfunction of the CNS-heart axis in mouse models of Huntington's disease.
@en
prefLabel
Dysfunction of the CNS-heart axis in mouse models of Huntington's disease.
@ast
Dysfunction of the CNS-heart axis in mouse models of Huntington's disease.
@en
P2093
P2860
P50
P1433
P1476
Dysfunction of the CNS-heart axis in mouse models of Huntington's disease.
@en
P2093
Andrea Protti
Donna L Smith
Georgina F Osborne
Ivan Rattray
Jim Rosinski
Linda Inuabasi
Marie K Bondulich
Sophie A Franklin
Thomas Muller
P2860
P304
P356
10.1371/JOURNAL.PGEN.1004550
P577
2014-08-07T00:00:00Z