Could isoenzyme-selective phosphodiesterase inhibitors render bronchodilator therapy redundant in the treatment of bronchial asthma?
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Differential effect of phosphodiesterase inhibitors on IL-13 release from peripheral blood mononuclear cellsIdentification and quantification of phosphodiesterase 4 subtypes in CD4 and CD8 lymphocytes from healthy and asthmatic subjectsAnti-spasmogenic activity of isoenzyme-selective phosphodiesterase inhibitors in guinea-pig trachealis.Inhibitors of cyclic nucleotide phosphodiesterase isozymes type-III and type-IV suppress mitogenesis of rat mesangial cells.Effect of selective phosphodiesterase 3 inhibition on the early and late asthmatic responses to inhaled allergen.Identification of cyclic AMP phosphodiesterases 3, 4 and 7 in human CD4+ and CD8+ T-lymphocytes: role in regulating proliferation and the biosynthesis of interleukin-2Effects of agents which elevate cyclic AMP on guinea-pig eosinophil homotypic aggregationPossible role of cyclic AMP phosphodiesterases in the actions of ibudilast on eosinophil thromboxane generation and airways smooth muscle toneTreatment of chronic obstructive pulmonary disease with roflumilast, a new phosphodiesterase 4 inhibitor.Roflumilast: first phosphodiesterase 4 inhibitor approved for treatment of COPD.Update on roflumilast, a phosphodiesterase 4 inhibitor for the treatment of chronic obstructive pulmonary diseaseSuppression of eosinophil function by RP 73401, a potent and selective inhibitor of cyclic AMP-specific phosphodiesterase: comparison with rolipram.Isoenzyme selective phosphodiesterase inhibitors: potential clinical uses.New perspectives on basic mechanisms in lung disease. 3. Drug intervention in asthma: present and future.Molecular mechanisms of antiasthma therapy.Phosphodiesterase isozymes: molecular targets for novel antiasthma agents.Phosphodiesterase 4 in macrophages: relationship between cAMP accumulation, suppression of cAMP hydrolysis and inhibition of [3H]R-(-)-rolipram binding by selective inhibitorsDifferential regulation of TNF-alpha and IL-1beta production from endotoxin stimulated human monocytes by phosphodiesterase inhibitors.Differential effect of phosphodiesterase 4 inhibitors on the proliferation of human peripheral blood mononuclear cells from normals and subjects with atopic dermatitis.Acute versus chronic administration of phosphodiesterase inhibitors on allergen-induced pulmonary cell influx in sensitized guinea-pigs.Effects of SCA40 on human isolated bronchus and human polymorphonuclear leukocytes: comparison with rolipram, SKF94120 and levcromakalim.Differential effects of non-selective and selective phosphodiesterase inhibitors on human eosinophil functions.A comparison of the inhibitory activity of selective PDE4 inhibitors on eosinophil recruitment in guinea pig skin.Induction of phosphodiesterases 3B, 4A4, 4D1, 4D2, and 4D3 in Jurkat T-cells and in human peripheral blood T-lymphocytes by 8-bromo-cAMP and Gs-coupled receptor agonists. Potential role in beta2-adrenoreceptor desensitization.The effect of zardaverine, an inhibitor of phosphodiesterase isoenzymes III and IV, on endotoxin-induced airway changes in rats.
P2860
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P2860
Could isoenzyme-selective phosphodiesterase inhibitors render bronchodilator therapy redundant in the treatment of bronchial asthma?
description
1992 nî lūn-bûn
@nan
1992 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1992 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
name
Could isoenzyme-selective phos ...... treatment of bronchial asthma?
@ast
Could isoenzyme-selective phos ...... treatment of bronchial asthma?
@en
type
label
Could isoenzyme-selective phos ...... treatment of bronchial asthma?
@ast
Could isoenzyme-selective phos ...... treatment of bronchial asthma?
@en
prefLabel
Could isoenzyme-selective phos ...... treatment of bronchial asthma?
@ast
Could isoenzyme-selective phos ...... treatment of bronchial asthma?
@en
P1476
Could isoenzyme-selective phos ...... treatment of bronchial asthma?
@en
P2093
Giembycz MA
P304
P356
10.1016/0006-2952(92)90160-K
P407
P577
1992-05-01T00:00:00Z