A system for the targeted amplification of bacterial gene clusters multiplies antibiotic yield in Streptomyces coelicolor.
about
The mycobacterial transcriptional regulator whiB7 gene links redox homeostasis and intrinsic antibiotic resistance.Combined gene cluster engineering and precursor feeding to improve gougerotin production in Streptomyces graminearus.Genome engineering and direct cloning of antibiotic gene clusters via phage ϕBT1 integrase-mediated site-specific recombination in Streptomyces.Precise cloning and tandem integration of large polyketide biosynthetic gene cluster using Streptomyces artificial chromosome system.Activity-Independent Discovery of Secondary Metabolites Using Chemical Elicitation and Cheminformatic InferenceCopy number change: evolving views on gene amplification.Genetic manipulation of secondary metabolite biosynthesis for improved production in Streptomyces and other actinomycetes.Engineering microbial hosts for production of bacterial natural productsAn insight into the "-omics" based engineering of streptomycetes for secondary metabolite overproduction.Integrated metabolomics approach facilitates discovery of an unpredicted natural product suite from Streptomyces coelicolor M145.The resolution and regeneration of a cointegrate plasmid reveals a model for plasmid evolution mediated by conjugation and oriT site-specific recombination.Increased Biosynthetic Gene Dosage in a Genome-Reduced Defensive Bacterial Symbiont.Effect of Extracellular Tyrosinase on the Expression Level of P450, Fpr, and Fdx and Ortho-hydroxylation of Daidzein in Streptomyces avermitilis.Development and application of a T7 RNA polymerase-dependent expression system for antibiotic production improvement in Streptomyces.Iterative marker excision system.Reconstruction of a hybrid nucleoside antibiotic gene cluster based on scarless modification of large DNA fragments.Enhanced production of validamycin A in Streptomyces hygroscopicus 5008 by engineering validamycin biosynthetic gene cluster.TAR cloning and integrated overexpression of 6-demethylchlortetracycline biosynthetic gene cluster in Streptomyces aureofaciens.Genetic approaches to generate hyper-producing strains of goadsporin: the relationships between productivity and gene duplication in secondary metabolite biosynthesis.Synthetic Biology of Antibiotic ProductionRegulation of antibiotic biosynthesis in actinomycetes: Perspectives and challenges
P2860
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P2860
A system for the targeted amplification of bacterial gene clusters multiplies antibiotic yield in Streptomyces coelicolor.
description
2011 nî lūn-bûn
@nan
2011 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
A system for the targeted ampl ...... ld in Streptomyces coelicolor.
@ast
A system for the targeted ampl ...... ld in Streptomyces coelicolor.
@en
type
label
A system for the targeted ampl ...... ld in Streptomyces coelicolor.
@ast
A system for the targeted ampl ...... ld in Streptomyces coelicolor.
@en
prefLabel
A system for the targeted ampl ...... ld in Streptomyces coelicolor.
@ast
A system for the targeted ampl ...... ld in Streptomyces coelicolor.
@en
P2093
P2860
P356
P1476
A system for the targeted ampl ...... ld in Streptomyces coelicolor.
@en
P2093
Charles J Thompson
Jan Burian
Koji Yanai
Mervyn J Bibb
Takeshi Murakami
P2860
P304
16020-16025
P356
10.1073/PNAS.1108124108
P407
P577
2011-09-08T00:00:00Z