A biochemical rationale for the discrete behavior of nitroxyl and nitric oxide in the cardiovascular system. - Wikidata - awgldk - TriplyDB

A biochemical rationale for the discrete behavior of nitroxyl and nitric oxide in the cardiovascular system.

A biochemical rationale for the discrete behavior of nitroxyl and nitric oxide in the cardiovascular system.

http://www.wikidata.org/entity/Q35234291

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Nitrosopumilus maritimus genome reveals unique mechanisms for nitrification and autotrophy in globally distributed marine crenarchaea Nitroxyl (HNO): A Reduced Form of Nitric Oxide with Distinct Chemical, Pharmacological, and Therapeutic Properties Gene expression profiles of NO- and HNO-donor treated breast cancer cells: insights into tumor response and resistance pathways Fifty years of diazeniumdiolate research. From laboratory curiosity to broad-spectrum biomedical advances Mn porphyrin-based SOD mimic, MnTnHex-2-PyP(5+), and non-SOD mimic, MnTBAP(3-), suppressed rat spinal cord ischemia/reperfusion injury via NF-κB pathways Signaling and stress: The redox landscape in NOS2 biology Inhibition of tubulin polymerization by hypochlorous acid and chloramines Photoinduced release of nitroxyl and nitric oxide from diazeniumdiolates Reactions of HNO with heme proteins: new routes to HNO-heme complexes and insight into physiological effects.Dual mechanisms of HNO generation by a nitroxyl prodrug of the diazeniumdiolate (NONOate) class.Acyloxy nitroso compounds as nitroxyl (HNO) donors: kinetics, reactions with thiols, and vasodilation properties Nitroxyl activates SERCA in cardiac myocytes via glutathiolation of cysteine 674.Glutathione sulfinamide serves as a selective, endogenous biomarker for nitroxyl after exposure to therapeutic levels of donors.Analysis of the HNO and NO donating properties of alicyclic amine diazeniumdiolates.Nitroxyl (HNO) reacts with molecular oxygen and forms peroxynitrite at physiological pH. Biological Implications.The specificity of nitroxyl chemistry is unique among nitrogen oxides in biological systems.HNO and NO release from a primary amine-based diazeniumdiolate as a function of pH The chemistry of nitroxyl-releasing compounds.Rapid and selective nitroxyl (HNO) trapping by phosphines: kinetics and new aqueous ligations for HNO detection and quantitation.Orthogonal properties of the redox siblings nitroxyl and nitric oxide in the cardiovascular system: a novel redox paradigm.Mechanism of pH-dependent decomposition of monoalkylamine diazeniumdiolates to form HNO and NO, deduced from the model compound methylamine diazeniumdiolate, density functional theory, and CBS-QB3 calculations Chemotherapeutic potential of diazeniumdiolate-based aspirin prodrugs in breast cancer.The chemistry and biology of nitroxyl (HNO): a chemically unique species with novel and important biological activity.Design and Synthesis of Near-infrared Fluorescent Probes for Imaging of Biological Nitroxyl.Nitroxyl-mediated disulfide bond formation between cardiac myofilament cysteines enhances contractile function.Ring expansions of acyloxy nitroso compounds Biological signaling by small inorganic molecules The pharmacology of nitroxyl (HNO) and its therapeutic potential: not just the Janus face of NO Meningeal blood flow is controlled by H2 S-NO crosstalk activating a HNO-TRPA1-CGRP signalling pathway.Pharmacological characterization of 1-nitrosocyclohexyl acetate, a long-acting nitroxyl donor that shows vasorelaxant and antiaggregatory effects.The potential of Angeli's salt to decrease nitric oxide scavenging by plasma hemoglobin.Modeling heme proteins using atomistic simulations.Angeli's salt counteracts the vasoactive effects of elevated plasma hemoglobin.The nitroxyl donor, Angeli's salt, inhibits inflammatory hyperalgesia in rats.Generation of nitroxyl by heme protein-mediated peroxidation of hydroxylamine but not N-hydroxy-L-arginine.Recent advances in the chemical biology of nitroxyl (HNO) detection and generation.Identification of nitroxyl-induced modifications in human platelet proteins using a novel mass spectrometric detection method.The effects of nitroxyl (HNO) on H₂O₂ metabolism and possible mechanisms of HNO signaling.The inhibitors of histone deacetylase suberoylanilide hydroxamate and trichostatin A release nitric oxide upon oxidation The emergence of nitroxyl (HNO) as a pharmacological agent.

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A biochemical rationale for the discrete behavior of nitroxyl and nitric oxide in the cardiovascular system.

http://www.wikidata.org/entity/Q35234291

description

2003 nî lūn-bûn

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2003 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2003年の論文

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A biochemical rationale for th ...... in the cardiovascular system.

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Proceedings of the National Academy of Sciences of the United States of America

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Nazareno Paolocci

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P2860

Molecular physiology of amylin

Bradykinin-induced release of calcitonin gene-related peptide from capsaicin-sensitive nerves in guinea-pig atria: mechanism of action and calcium requirements

Nitroxyl and its anion in aqueous solutions: spin states, protic equilibria, and reactivities toward oxygen and nitric oxide

Unique oxidative mechanisms for the reactive nitrogen oxide species, nitroxyl anion.

Nitroxyl anion exerts redox-sensitive positive cardiac inotropy in vivo by calcitonin gene-related peptide signaling.

Mechanisms of cell death governed by the balance between nitrosative and oxidative stress.

The reduction potential of nitric oxide (NO) and its importance to NO biochemistry.

On the acidity and reactivity of HNO in aqueous solution and biological systems.

Positive inotropic and lusitropic effects of HNO/NO- in failing hearts: independence from beta-adrenergic signaling.

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9196-9201

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100

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12865500

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Aparato circulatorio

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