Reverse intrinsic activity of antagonists on G protein-coupled receptors.
about
Inverse agonism of histamine H2 antagonist accounts for upregulation of spontaneously active histamine H2 receptorsHigh constitutive activity of native H3 receptors regulates histamine neurons in brain.Structure and regulation of opioid receptors.Quantification of receptor interactions using binding methods.Gsalpha-selective G protein antagonists.Inhibition of constitutive signaling of Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor by protein kinases in mammalian cells in cultureHuman interferon-gamma-inducible protein 10 (IP-10) inhibits constitutive signaling of Kaposi's sarcoma-associated herpesvirus G protein-coupled receptorChemokines activate Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor in mammalian cells in culture.Mathematical analysis of the sodium sensitivity of the human histamine H3 receptorLigand binding to transmembrane receptors on intact cells or membrane vesicles measured in a homogeneous 1-microliter assay format.Chlorpropamide upregulates antidiuretic hormone receptors and unmasks constitutive receptor signaling.Kinetics of ternary complex formation with fusion proteins composed of the A(1)-adenosine receptor and G protein alpha-subunits.Modulation of basal intracellular calcium by inverse agonists and phorbol myristate acetate in rat-1 fibroblasts stably expressing alpha1d-adrenoceptors.High constitutive activity of the human formyl peptide receptor.Structural instability of a constitutively active G protein-coupled receptor. Agonist-independent activation due to conformational flexibility.Functional reconstitution in situ of 5-hydroxytryptamine2c (5HT2c) receptors with alphaq and inverse agonism of 5HT2c receptor antagonists.Analysis of inverse agonism at the delta opioid receptor after expression in Rat 1 fibroblasts.Detection and analysis of agonist-induced formation of the complex of the stimulatory guanine nucleotide-binding protein with adenylate cyclase in intact wild-type and beta 2-adrenoceptor-expressing NG108-15 cells.Evidence that depletion of internal calcium stores sensitive to noradrenaline elicits a contractile response dependent on extracellular calcium in rat aorta.Binding and structure-activity-relation of benzo[f]isoquinoline- and norcodeinone-derivatives at mu-opioid receptors in the rat cerebral cortex.Solubilization and characterization of GABAB receptor binding sites from porcine brain synaptic membranesActivation of constitutive 5-hydroxytryptamine(1B) receptor by a series of mutations in the BBXXB motif: positioning of the third intracellular loop distal junction and its G(o)alpha protein interactionsInverse agonist activities of beta-adrenoceptor antagonists in rat myocardium.Modulation of forskolin-mediated adenylyl cyclase activation by constitutively active G(S)-coupled receptors.Regulation of basal adenylate cyclase activity in neuroblastoma x glioma hybrid, NG108-15, cells transfected to express the human beta 2 adrenoceptor: evidence for empty receptor stimulation of the adenylate cyclase cascade.Up-regulation of a constitutively active form of the beta2-adrenoceptor by sustained treatment with inverse agonists but not antagonists.Functional evidence of inverse agonism in vascular smooth muscle.Mechanisms of inverse agonism of antipsychotic drugs at the D(2) dopamine receptor: use of a mutant D(2) dopamine receptor that adopts the activated conformation.Characterization of sumatriptan-induced contractions in human isolated blood vessels using selective 5-HT(1B) and 5-HT(1D) receptor antagonists and in situ hybridization.Agonist-dependent and -independent dopamine-1-like receptor signalling differentially regulates downstream effectors.Agonist- and antagonist-induced plasticity of rat 5-HT1A receptor in hippocampal cell culture.The role of 5-HT2C receptors in affective disorders.
P2860
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P2860
Reverse intrinsic activity of antagonists on G protein-coupled receptors.
description
1992 nî lūn-bûn
@nan
1992 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1992 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
name
Reverse intrinsic activity of antagonists on G protein-coupled receptors.
@ast
Reverse intrinsic activity of antagonists on G protein-coupled receptors.
@en
type
label
Reverse intrinsic activity of antagonists on G protein-coupled receptors.
@ast
Reverse intrinsic activity of antagonists on G protein-coupled receptors.
@en
prefLabel
Reverse intrinsic activity of antagonists on G protein-coupled receptors.
@ast
Reverse intrinsic activity of antagonists on G protein-coupled receptors.
@en
P1476
Reverse intrinsic activity of antagonists on G protein-coupled receptors.
@en
P2093
Freissmuth M
P304
P356
10.1016/0165-6147(92)90116-N
P577
1992-10-01T00:00:00Z