Hypothalamic-pituitary-adrenal axis modulation of GABAergic neuroactive steroids influences ethanol sensitivity and drinking behavior - Wikidata - awgldk - TriplyDB

Hypothalamic-pituitary-adrenal axis modulation of GABAergic neuroactive steroids influences ethanol sensitivity and drinking behavior

Hypothalamic-pituitary-adrenal axis modulation of GABAergic neuroactive steroids influences ethanol sensitivity and drinking behavior

http://www.wikidata.org/entity/Q35236873

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Neurosteroids and GABA(A) Receptor Interactions: A Focus on Stress Neurosteroids: endogenous role in the human brain and therapeutic potentials Alcohol response and consumption in adolescent rhesus macaques: life history and genetic influences Recent developments in the significance and therapeutic relevance of neuroactive steroids--Introduction to the special issue GABAA receptor-acting neurosteroids: a role in the development and regulation of the stress response Chronic ethanol exposure produces tolerance to elevations in neuroactive steroids: mechanisms and reversal by exogenous ACTH Independent contributions of alcohol and stress axis hormones to painful peripheral neuropathy.Neurosteroid influences on sensitivity to ethanol The role of GABA(A) receptors in the acute and chronic effects of ethanol: a decade of progress Simultaneous quantification of GABAergic 3alpha,5alpha/3alpha,5beta neuroactive steroids in human and rat serum.Neurosteroids and GABAergic signaling in health and disease Differential effects of ethanol on serum GABAergic 3alpha,5alpha/3alpha,5beta neuroactive steroids in mice, rats, cynomolgus monkeys, and humans.Genetic analysis of the neurosteroid deoxycorticosterone and its relation to alcohol phenotypes: identification of QTLs and downstream gene regulation.Divergent neuroactive steroid responses to stress and ethanol in rat and mouse strains: relevance for human studies.Failure of acute ethanol administration to alter cerebrocortical and hippocampal allopregnanolone levels in C57BL/6J and DBA/2J mice.CRF-1 antagonist and CRF-2 agonist decrease binge-like ethanol drinking in C57BL/6J mice independent of the HPA axis.The role of GABA(A) receptors in the development of alcoholism Neuroimaging insights into the role of cortical GABA systems and the influence of nicotine on the recovery from alcohol dependence.Neurotransmitter and neuromodulator genes associated with a history of depressive symptoms in individuals with alcohol dependence Role of acetaldehyde in ethanol-induced elevation of the neuroactive steroid 3alpha-hydroxy-5alpha-pregnan-20-one in rats OPRM1 gene variation influences hypothalamic-pituitary-adrenal axis function in response to a variety of stressors in rhesus macaques.Pathway based analysis of genotypes in relation to alcohol dependence.Monkey alcohol tissue research resource: banking tissues for alcohol research.Corticosterone enhances the potency of ethanol against hippocampal long-term potentiation via local neurosteroid synthesis.The effects of chronic ethanol self-administration on hippocampal serotonin transporter density in monkeys.Role of anticonvulsant and antiepileptogenic neurosteroids in the pathophysiology and treatment of epilepsy.Alcohol exposure during late adolescence increases drinking in adult Wistar rats, an effect that is not reduced by finasteride Differential hypothalamic-pituitary-adrenal activation of the neuroactive steroids pregnenolone sulfate and deoxycorticosterone in healthy controls and alcohol-dependent subjects Neurosteroidogenesis Today: Novel Targets for Neuroactive Steroid Synthesis and Action and Their Relevance for Translational Research.Neurosteroids, stress and depression: potential therapeutic opportunities.Tolerance to Ethanol or Nicotine Results in Increased Ethanol Self-Administration and Long-Term Depression in the Dorsolateral Striatum High-resolution time course analysis of gene expression from pituitary Ovarian hormones and the heterogeneous receptor mechanisms mediating the discriminative stimulus effects of ethanol in female rats.Introduction to the special issue "Pharmacotherapies for the treatment of alcohol abuse and dependence" and a summary of patents targeting other neurotransmitter systems.Studies using macaque monkeys to address excessive alcohol drinking and stress interactions.Voluntary ethanol consumption reduces GABAergic neuroactive steroid (3α,5α)3-hydroxypregnan-20-one (3α,5α-THP) in the amygdala of the cynomolgus monkey.Initial genetic dissection of serum neuroactive steroids following chronic intermittent ethanol across BXD mouse strains.Neuroactive Steroid (3α,5α)3-hydroxypregnan-20-one (3α,5α-THP) and Pro-inflammatory Cytokine MCP-1 Levels in Hippocampus CA1 are Correlated with Voluntary Ethanol Consumption in Cynomolgus Monkey.Dynamic Adaptation in Neurosteroid Networks in Response to Alcohol.Cellular GABAergic Neuroactive Steroid (3α,5α)-3-Hydroxy-Pregnan-20-One (3α,5α-THP) Immunostaining Levels Are Increased in the Ventral Tegmental Area of Human Alcohol Use Disorder Patients: A Postmortem Study.

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Hypothalamic-pituitary-adrenal axis modulation of GABAergic neuroactive steroids influences ethanol sensitivity and drinking behavior

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2006年の論文

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Dialogues in Clinical Neuroscience

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A Leslie Morrow

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Kathleen A Grant

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Anticonvulsant activity of androsterone and etiocholanolone.

Selective serotonin reuptake inhibitors directly alter activity of neurosteroidogenic enzymes

Increase in the cerebrospinal fluid content of neurosteroids in patients with unipolar major depression who are receiving fluoxetine or fluvoxamine

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Ethanol rapidly induces steroidogenic acute regulatory protein expression and translocation in rat adrenal gland

Neurosteroid biosynthesis: genes for adrenal steroidogenic enzymes are expressed in the brain

Neuroactive Steroids are Altered in Schizophrenia and Bipolar Disorder: Relevance to Pathophysiology and Therapeutics

Stress, hypercortisolism and corticosteroid receptors in depression: implications for therapy.

Effect of repeated exposure to alcohol on the response of the hypothalamic-pituitary-adrenal axis of the rat: I. Role of changes in hypothalamic neuronal activity.

Excessive ethanol drinking following a history of dependence: animal model of allostasis.

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