CarD stabilizes mycobacterial open complexes via a two-tiered kinetic mechanism - Wikidata - awgldk - TriplyDB

CarD stabilizes mycobacterial open complexes via a two-tiered kinetic mechanism

CarD stabilizes mycobacterial open complexes via a two-tiered kinetic mechanism

http://www.wikidata.org/entity/Q35237024

about

Initial events in bacterial transcription initiation Mycobacterium tuberculosis Transcription Machinery: Ready To Respond to Host Attacks Drug Repurposing: Tolfenamic Acid Inactivates PrbP, a Transcriptional Accessory Protein in Liberibacter asiaticus Structural insights into the mycobacteria transcription initiation complex from analysis of X-ray crystal structures.Transcriptomic analysis of the stationary phase response regulator SpdR in Caulobacter crescentus.CarD uses a minor groove wedge mechanism to stabilize the RNA polymerase open promoter complex.Production and characterization of a highly pure RNA polymerase holoenzyme from Mycobacterium tuberculosis.Fluorescence Resonance Energy Transfer Characterization of DNA Wrapping in Closed and Open Escherichia coli RNA Polymerase-λP(R) Promoter Complexes Cooperative stabilization of Mycobacterium tuberculosis rrnAP3 promoter open complexes by RbpA and CarD.Structure and function of the mycobacterial transcription initiation complex with the essential regulator RbpA.Caulobacter crescentus CdnL is a non-essential RNA polymerase-binding protein whose depletion impairs normal growth and rRNA transcription.Conformational selection and induced fit as a useful framework for molecular motor mechanisms.Identification of the Tolfenamic Acid Binding Pocket in PrbP from Liberibacter asiaticus.RNA polymerase motions during promoter melting.Effects of Increasing the Affinity of CarD for RNA Polymerase on Mycobacterium tuberculosis Growth, rRNA Transcription, and Virulence.Early diagnosis and effective treatment regimens are the keys to tackle antimicrobial resistance in tuberculosis (TB): A report from Euroscicon's international TB Summit 2016.A Kinetic Signature for Parallel Pathways: Conformational Selection and Induced Fit. Links and Disconnects between Observed Relaxation Rates and Fractional Equilibrium Flux under Pseudo-First-Order Conditions.Domains within RbpA serve specific functional roles that regulate the expression of distinct mycobacterial gene subsets.

P2860

Q27026444-FFECCD8F-720C-4919-AA1B-0B221086FD56 Q28071015-0BDAA4AD-5798-49D0-A66E-A78E0A214E1E Q28821876-83ECE2CC-4A56-4E25-A19C-6212A1822EDE Q33906396-6E77D169-1D97-4D47-960F-8A0E18291076 Q35987861-DBCA8AB4-3885-47A8-A85A-B029074624F9 Q36120532-96D10DA6-290F-428D-81EF-A93B0346F38D Q36316140-2BD30831-1100-4960-ADEA-E2EB8E78F4A0 Q36795614-D15F5654-9F90-4D08-9C3F-E923307EE826 Q37228885-9B1EBC3E-17E5-4739-B827-2A39455B86AF Q37636565-5E4CEE6E-278D-4E12-8507-0D3A4FEA7318 Q37663177-9CBE8DDE-8F86-4F8A-93C4-0EC705F63BFC Q39130476-29A081D4-3C0D-46D1-AFA2-93CD54C657EB Q40063517-FA984580-6C7F-4FBD-A7A3-E6CCA0605615 Q40197974-5BDFF700-E78B-461A-9FA3-83365F018ADB Q40422721-F50CB785-B2B2-41A2-B24C-59F82530C3D7 Q40463792-E2ED535F-B675-468F-90CA-C37711A6317F Q46784154-E7E4F70A-6CBA-4D8E-AA08-CBA82E95C153 Q54229844-AFE7123A-8C2D-499D-8D7E-6FA6B81BBBE1

P2860

CarD stabilizes mycobacterial open complexes via a two-tiered kinetic mechanism

http://www.wikidata.org/entity/Q35237024

description

2015 nî lūn-bûn

@nan

2015 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2015 թվականի փետրվարին հրատարակված գիտական հոդված

@hy

2015年の論文

@ja

2015年論文

@yue

2015年論文

@zh-hant

2015年論文

@zh-hk

2015年論文

@zh-mo

2015年論文

@zh-tw

2015年论文

@wuu

name

CarD stabilizes mycobacterial open complexes via a two-tiered kinetic mechanism

@ast

CarD stabilizes mycobacterial open complexes via a two-tiered kinetic mechanism

@en

type

label

CarD stabilizes mycobacterial open complexes via a two-tiered kinetic mechanism

@ast

CarD stabilizes mycobacterial open complexes via a two-tiered kinetic mechanism

@en

prefLabel

CarD stabilizes mycobacterial open complexes via a two-tiered kinetic mechanism

@ast

CarD stabilizes mycobacterial open complexes via a two-tiered kinetic mechanism

@en

P1433

Q35237024-337F0531-8A02-4422-BD34-AFAA87D8A575

P1476

Q35237024-29C91DFD-6660-4571-8E39-E0F5A1A2581C

P2093

Q35237024-0B21CF55-1678-4471-96D6-E5541E908D5A

Q35237024-9347401E-8A3E-4CDB-9E0C-5B291722B5EE

Q35237024-DF1D4E3C-5425-41BD-9E3E-7B333735E975

Q35237024-E7549734-CFBB-4628-B12E-826FD9FEC2DD

P2860

Q35237024-03C3F87D-A97E-4C30-AF2C-5ADCFF1157F8

Q35237024-1B367C26-AE5A-4FDD-A4C6-7CA28216DDAE

Q35237024-1EACA66C-6B63-4CD1-89AC-2444DACC60EA

Q35237024-20D710BC-A6DB-4EC8-A601-905A0ED318AB

Q35237024-217173BB-EC1F-41A3-AE80-9F65BE118D09

Q35237024-2A5ED71F-CF54-4BC2-8AEC-02C0B1261556

Q35237024-2AD177AB-028F-45B0-932C-16A4FFD2F431

Q35237024-2FB3A059-749D-4CF8-915A-8FE8C13EDDA7

Q35237024-320673AF-507B-4C9D-93D3-34B8E2A1094C

Q35237024-324DE953-CC22-4F42-AC19-51ECD6358E47

P304

Q35237024-6ADB70CF-BC6B-4E7A-BB9A-E18077E07838

P31

Q35237024-97B7AA30-7E45-46DA-A26C-428DC47921BE

P356

Q35237024-4F038983-EE37-4F91-A839-5DD96B2EDC4E

P407

Q35237024-B3A9B73A-16C7-476C-B442-BFA4B147A3EC

P433

Q35237024-318B2D78-5AA1-4BFD-AD86-09AEEF28D961

P478

Q35237024-65951D80-710C-4540-84CF-B824A9BAFBA9

P50

Q35237024-68C948AE-FE08-46E6-A62E-ADFA03FFDC4D

P577

Q35237024-8AAC61D7-46C5-4811-9DEB-31F45EF50D9C

P5875

Q35237024-8EFCB7A8-FA44-4867-B0D7-F1CC64FFA9FA

P698

Q35237024-3417B645-DEA1-4717-A03A-616A95BB2565

P932

Q35237024-665DD765-6CB5-4233-A870-543E6300B556

P356

P1433

Nucleic Acids Research

P1476

CarD stabilizes mycobacterial open complexes via a two-tiered kinetic mechanism

@en

P2093

Ana Ruiz Manzano

http://www.w3.org/2001/XMLSchema#string

Ashley L Garner

http://www.w3.org/2001/XMLSchema#string

Christina L Stallings

http://www.w3.org/2001/XMLSchema#string

Jayan Rammohan

http://www.w3.org/2001/XMLSchema#string

P2860

Structural basis for the bacterial transcription-repair coupling factor/RNA polymerase interaction

Structure and function of CarD, an essential mycobacterial transcription factor

Interaction of CarD with RNA polymerase mediates Mycobacterium tuberculosis viability, rifampin resistance, and pathogenesis

CarD is an essential regulator of rRNA transcription required for Mycobacterium tuberculosis persistence

The gene expression data of Mycobacterium tuberculosis based on Affymetrix gene chips provide insight into regulatory and hypothetical genes.

CarD integrates three functional modules to promote efficient transcription, antibiotic tolerance, and pathogenesis in mycobacteria.

Mechanisms of transcriptional repression.

Distinct and contrasting transcription initiation patterns at Mycobacterium tuberculosis promoters.

Identification and characterization of a new Escherichia coli gene that is a dosage-dependent suppressor of a dnaK deletion mutation.

Mechanism of bacterial transcription initiation: RNA polymerase - promoter binding, isomerization to initiation-competent open complexes, and initiation of RNA synthesis

P304

3272-3285

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1093/NAR/GKV078

http://www.w3.org/2001/XMLSchema#string

P407

P433

6

http://www.w3.org/2001/XMLSchema#string

P478

43

http://www.w3.org/2001/XMLSchema#string

P50

P577

2015-02-19T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

272517979

http://www.w3.org/2001/XMLSchema#string

P698

25697505

http://www.w3.org/2001/XMLSchema#string

P932

4381055

http://www.w3.org/2001/XMLSchema#string