Microsomal prostaglandin E synthase-2 is not essential for in vivo prostaglandin E2 biosynthesis - Wikidata - awgldk - TriplyDB

Microsomal prostaglandin E synthase-2 is not essential for in vivo prostaglandin E2 biosynthesis

Microsomal prostaglandin E synthase-2 is not essential for in vivo prostaglandin E2 biosynthesis

http://www.wikidata.org/entity/Q35238520

about

Enzymes of the cyclooxygenase pathways of prostanoid biosynthesis Physiology and pathophysiology of cyclooxygenase-2 and prostaglandin E2 in the kidney Mice lacking mPGES-1 are resistant to lithium-induced polyuria.The impact of microsomal prostaglandin e synthase 1 on blood pressure is determined by genetic background.Prostaglandin E2 synthases in neurologic homeostasis and disease Identification and development of mPGES-1 inhibitors: where we are at?The still mysterious roles of cysteine-containing glutathione transferases in plants.Prostaglandins and inflammation.Distinct roles of central and peripheral prostaglandin E2 and EP subtypes in blood pressure regulation Prostaglandin E2 induction during mouse adenovirus type 1 respiratory infection regulates inflammatory mediator generation but does not affect viral pathogenesis.COX-2 but not mPGES-1 contributes to renal PGE2 induction and diabetic proteinuria in mice with type-1 diabetes.A major role for the EP4 receptor in regulation of renin.mPGES-2 deletion remarkably enhances liver injury in streptozotocin-treated mice via induction of GLUT2 Matrix metalloproteinase-dependent microsomal prostaglandin E synthase-1 expression in macrophages: role of TNF-α and the EP4 prostanoid receptor.Prostaglandin E(2) produced by the lung augments the effector phase of allergic inflammation.Associations between gene polymorphisms in fatty acid metabolism pathway and preterm delivery in a US urban black population.Eicosanoids in metabolic syndrome.Genetic deletion of microsomal prostaglandin E synthase-1 suppresses mouse mammary tumor growth and angiogenesis.Reduced T cell-dependent humoral immune response in microsomal prostaglandin E synthase-1 null mice is mediated by nonhematopoietic cells.Nitro-oleic acid protects against adriamycin-induced nephropathy in mice.Prostaglandin E(2) synthase inhibition as a therapeutic target.New Insights into the PPAR γ Agonists for the Treatment of Diabetic Nephropathy.Microsomal prostaglandin E synthase type 2 (mPGES2) is a glutathione-dependent heme protein, and dithiothreitol dissociates the bound heme to produce active prostaglandin E2 synthase in vitro Aggravation of acute kidney injury by mPGES-2 down regulation is associated with autophagy inhibition and enhanced apoptosis.Expression of prostaglandin E synthases in periodontitis immunolocalization and cellular regulation.COX-2 mediates PM2.5-induced apoptosis and inflammation in vascular endothelial cells.Identification of key residues determining species differences in inhibitor binding of microsomal prostaglandin E synthase-1 mPGES-1 deletion potentiates urine concentrating capability after water deprivation.Lipopolysaccharide (LPS)-mediated priming of toll-like receptor 4 enhances oxidant-induced prostaglandin E2 biosynthesis in primary murine macrophages.Prostaglandin terminal synthases as novel therapeutic targets.Prostaglandin E2 in the Regulation of Water Transport in Renal Collecting Ducts.Minocycline reduces prostaglandin E synthase expression and 8-isoprostane formation in LPS-activated primary rat microglia.Mitochondrial oxidative stress activates COX-2/mPGES-1/PGE2 cascade induced by albumin in renal proximal tubular cells.

P2860

Q24630614-33650817-CB88-48EA-93A0-4A4F92FD8CCE Q26771378-72218810-8C77-4C7E-9658-13E1CD528ECE Q33570060-6C0ED694-4C9A-423C-8DCE-D3E754E36B44 Q33720134-2B23C068-33A1-40CD-94D2-BD428D672855 Q33751084-348AB631-B28F-465E-BADE-906E7EC5F147 Q34056458-331FCB39-F2D1-4E83-9905-2D2B2D0F3E0D Q34068151-C8BF80EF-C0FA-4397-8E43-D18BF440E90B Q34179727-3627728C-4D70-4599-8274-D5C4CF27B007 Q34281269-5A28B15A-9300-45B5-9AF4-1E45EAA9F5C6 Q35023278-0C143E6F-9D06-4492-B33E-868CBF3B3DC2 Q35199315-E7CEAB69-349D-4062-8142-E1426C86A491 Q35543233-AC65B7AC-1958-4D7F-8821-793E052CE790 Q35654707-1BE227D3-E84A-42D4-9678-0FA8EC8C205C Q35740060-7CE91EA6-7BB4-42DA-A086-2B6E313C3C06 Q35884115-D97B6A6E-E518-4DAE-82E0-F0D9DA49814E Q35991776-D5479A1F-89C2-45B9-B89E-357CDB519FED Q36911098-9410E852-C9CD-41BC-A990-D901D6CCA28B Q37315920-2B14B36C-3544-480C-8EF7-FFA574A234A0 Q37334207-94F69D5E-15D3-4D8C-AAEC-C632537005AC Q37439735-DADF0AAE-BF54-4B98-81BA-0D24DF9D9063 Q37521092-CE1FEA7A-CD46-44B0-B1FB-08D2DB6D34C5 Q37590946-68BB4712-AD4C-4F86-9690-14B9D4406CDF Q39614692-681EC682-F63E-44F2-96B8-91E7E3FC185E Q41581676-584E6985-99F2-47A6-B4D8-AE075858B6E3 Q41823003-5B9CBA9C-9AB1-4AC8-A772-AC49E4CE2B1A Q42059971-376ACA6D-50A1-4893-96BA-793C9F537541 Q42427981-5532E2A7-0BCF-4566-9D76-6BF6AD08A718 Q42538078-5DB8B5C4-B984-4A13-BCA5-A65BF5622FA3 Q46256979-4EE85D9A-D9C3-4E07-B16D-DA0F714FF468 Q46263032-51D005DD-278E-42FF-8195-62781DE71380 Q47351317-B9333C4B-F2C2-4F35-AA12-9F28C5C4B1E4 Q54518414-E5423565-5116-4609-B866-FC7751232FAC Q55024909-D4C6DA1C-0744-4C8F-98A4-19A1FEC37260

P2860

Microsomal prostaglandin E synthase-2 is not essential for in vivo prostaglandin E2 biosynthesis

http://www.wikidata.org/entity/Q35238520

description

2008 nî lūn-bûn

@nan

2008 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2008 թվականի նոյեմբերին հրատարակված գիտական հոդված

@hy

2008年の論文

@ja

2008年論文

@yue

2008年論文

@zh-hant

2008年論文

@zh-hk

2008年論文

@zh-mo

2008年論文

@zh-tw

2008年论文

@wuu

name

Microsomal prostaglandin E syn ...... prostaglandin E2 biosynthesis

@ast

Microsomal prostaglandin E syn ...... prostaglandin E2 biosynthesis

@en

type

label

Microsomal prostaglandin E syn ...... prostaglandin E2 biosynthesis

@ast

Microsomal prostaglandin E syn ...... prostaglandin E2 biosynthesis

@en

prefLabel

Microsomal prostaglandin E syn ...... prostaglandin E2 biosynthesis

@ast

Microsomal prostaglandin E syn ...... prostaglandin E2 biosynthesis

@en

P1433

Q35238520-F48B40B0-D09A-433F-9EC7-440D31732B6A

P1476

Q35238520-8B613FC6-94ED-4F95-90FD-439BEFE931E2

P2093

Q35238520-4141974A-889F-4C01-B1C6-802C611C1564

Q35238520-614E0FDB-E53C-445B-821B-9F2366C24789

Q35238520-8410D70E-4F08-4261-A670-4B787BD704F1

Q35238520-A84D0AD3-05CF-4554-BD76-647ADA14CB7A

Q35238520-B1525F9D-8082-4F4E-B8C7-1708327569B7

Q35238520-BA94FD8E-FE17-4351-9F18-55EF3BF005B4

Q35238520-C6416EA8-3A01-420F-B52E-FC8A51083B44

Q35238520-F64A4711-478F-4A42-8130-35AF2EFB168D

Q35238520-FF7EA5FD-BC64-4E18-B21D-41BF8268F1DE

P2860

Q35238520-07155892-D4FB-4CC5-ACF7-0021E86F8828

Q35238520-0F52FAEC-8281-4F63-8B11-9B1006748CD3

Q35238520-12B10054-007D-44F3-9C7F-65C9BD177F38

Q35238520-256B3EC8-8AA3-466E-8DA9-F5420934374F

Q35238520-2682B6F1-80C2-4425-99AB-08F3FD47C6A2

Q35238520-283F7DE3-C179-4ADB-B421-47B0D5A83C0C

Q35238520-29C00D7B-1161-4721-BEDA-CDF129634E8C

Q35238520-2A9C7350-3322-4026-BAC5-612C93F1ED84

Q35238520-37C3880E-A85D-432A-A452-806FF9B17496

Q35238520-4016C7FE-8794-4C19-BDEE-25732D140344

P304

Q35238520-924494D8-F863-4C38-82F8-81137EF0B540

P31

Q35238520-60D1A858-A976-47AB-9E70-600BE30B36D8

P356

Q35238520-B31F9667-87FF-4B70-AB45-86FBE1BE428D

P433

Q35238520-12DA4C6D-7E24-4C95-86DE-47EC4BCAE3AD

P478

Q35238520-9BBED752-7F34-40C0-8A09-A017564973CC

P577

Q35238520-68035E34-0599-46DD-8416-AA3A0C15AA7F

P5875

Q35238520-FF8C80D2-72C8-40AF-BF36-7AEB78FC967F

P698

Q35238520-E3EBD9B9-0ABD-4DB1-A588-FB2DDB2C9F90

P932

Q35238520-CA42396C-1AF3-4670-96AF-6B1AE40D534F

P356

J.PROSTAGLANDINS.2008.10.003

P1433

Prostaglandins and Other Lipid Mediators

P1476

Microsomal prostaglandin E syn ...... prostaglandin E2 biosynthesis

@en

P2093

Beverly H Koller

http://www.w3.org/2001/XMLSchema#string

I-Ming Wang

http://www.w3.org/2001/XMLSchema#string

John Snouwaert

http://www.w3.org/2001/XMLSchema#string

Laurent P Audoly

http://www.w3.org/2001/XMLSchema#string

Leigh A Jania

http://www.w3.org/2001/XMLSchema#string

Michael G Backlund

http://www.w3.org/2001/XMLSchema#string

Nicholas A Foley

http://www.w3.org/2001/XMLSchema#string

Patsy Clark

http://www.w3.org/2001/XMLSchema#string

Subhashini Chandrasekharan

http://www.w3.org/2001/XMLSchema#string

P2860

Identification of human prostaglandin E synthase: a microsomal, glutathione-dependent, inducible enzyme, constituting a potential novel drug target

Molecular identification of cytosolic prostaglandin E2 synthase that is functionally coupled with cyclooxygenase-1 in immediate prostaglandin E2 biosynthesis

The tripartite motif family identifies cell compartments.

Mixed messages: modulation of inflammation and immune responses by prostaglandins and thromboxanes

Impaired inflammatory and pain responses in mice lacking an inducible prostaglandin E synthase

Functional discovery via a compendium of expression profiles.

Prostaglandin E synthase

HPRT-deficient (Lesch-Nyhan) mouse embryos derived from germline colonization by cultured cells

Carrageenan-induced paw edema in rat elicits a predominant prostaglandin E2 (PGE2) response in the central nervous system associated with the induction of microsomal PGE2 synthase-1

Regulation of prostaglandin E2 biosynthesis by inducible membrane-associated prostaglandin E2 synthase that acts in concert with cyclooxygenase-2

P304

73-81

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1016/J.PROSTAGLANDINS.2008.10.003

http://www.w3.org/2001/XMLSchema#string

P433

3-4

http://www.w3.org/2001/XMLSchema#string

P478

88

http://www.w3.org/2001/XMLSchema#string

P577

2008-11-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

23474772

http://www.w3.org/2001/XMLSchema#string

P698

19010439

http://www.w3.org/2001/XMLSchema#string

P932

3182462

http://www.w3.org/2001/XMLSchema#string