Microsomal prostaglandin E synthase-2 is not essential for in vivo prostaglandin E2 biosynthesis
about
Enzymes of the cyclooxygenase pathways of prostanoid biosynthesisPhysiology and pathophysiology of cyclooxygenase-2 and prostaglandin E2 in the kidneyMice lacking mPGES-1 are resistant to lithium-induced polyuria.The impact of microsomal prostaglandin e synthase 1 on blood pressure is determined by genetic background.Prostaglandin E2 synthases in neurologic homeostasis and diseaseIdentification and development of mPGES-1 inhibitors: where we are at?The still mysterious roles of cysteine-containing glutathione transferases in plants.Prostaglandins and inflammation.Distinct roles of central and peripheral prostaglandin E2 and EP subtypes in blood pressure regulationProstaglandin E2 induction during mouse adenovirus type 1 respiratory infection regulates inflammatory mediator generation but does not affect viral pathogenesis.COX-2 but not mPGES-1 contributes to renal PGE2 induction and diabetic proteinuria in mice with type-1 diabetes.A major role for the EP4 receptor in regulation of renin.mPGES-2 deletion remarkably enhances liver injury in streptozotocin-treated mice via induction of GLUT2Matrix metalloproteinase-dependent microsomal prostaglandin E synthase-1 expression in macrophages: role of TNF-α and the EP4 prostanoid receptor.Prostaglandin E(2) produced by the lung augments the effector phase of allergic inflammation.Associations between gene polymorphisms in fatty acid metabolism pathway and preterm delivery in a US urban black population.Eicosanoids in metabolic syndrome.Genetic deletion of microsomal prostaglandin E synthase-1 suppresses mouse mammary tumor growth and angiogenesis.Reduced T cell-dependent humoral immune response in microsomal prostaglandin E synthase-1 null mice is mediated by nonhematopoietic cells.Nitro-oleic acid protects against adriamycin-induced nephropathy in mice.Prostaglandin E(2) synthase inhibition as a therapeutic target.New Insights into the PPAR γ Agonists for the Treatment of Diabetic Nephropathy.Microsomal prostaglandin E synthase type 2 (mPGES2) is a glutathione-dependent heme protein, and dithiothreitol dissociates the bound heme to produce active prostaglandin E2 synthase in vitroAggravation of acute kidney injury by mPGES-2 down regulation is associated with autophagy inhibition and enhanced apoptosis.Expression of prostaglandin E synthases in periodontitis immunolocalization and cellular regulation.COX-2 mediates PM2.5-induced apoptosis and inflammation in vascular endothelial cells.Identification of key residues determining species differences in inhibitor binding of microsomal prostaglandin E synthase-1mPGES-1 deletion potentiates urine concentrating capability after water deprivation.Lipopolysaccharide (LPS)-mediated priming of toll-like receptor 4 enhances oxidant-induced prostaglandin E2 biosynthesis in primary murine macrophages.Prostaglandin terminal synthases as novel therapeutic targets.Prostaglandin E2 in the Regulation of Water Transport in Renal Collecting Ducts.Minocycline reduces prostaglandin E synthase expression and 8-isoprostane formation in LPS-activated primary rat microglia.Mitochondrial oxidative stress activates COX-2/mPGES-1/PGE2 cascade induced by albumin in renal proximal tubular cells.
P2860
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P2860
Microsomal prostaglandin E synthase-2 is not essential for in vivo prostaglandin E2 biosynthesis
description
2008 nî lūn-bûn
@nan
2008 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Microsomal prostaglandin E syn ...... prostaglandin E2 biosynthesis
@ast
Microsomal prostaglandin E syn ...... prostaglandin E2 biosynthesis
@en
type
label
Microsomal prostaglandin E syn ...... prostaglandin E2 biosynthesis
@ast
Microsomal prostaglandin E syn ...... prostaglandin E2 biosynthesis
@en
prefLabel
Microsomal prostaglandin E syn ...... prostaglandin E2 biosynthesis
@ast
Microsomal prostaglandin E syn ...... prostaglandin E2 biosynthesis
@en
P2093
P2860
P1476
Microsomal prostaglandin E syn ...... prostaglandin E2 biosynthesis
@en
P2093
Beverly H Koller
I-Ming Wang
John Snouwaert
Laurent P Audoly
Leigh A Jania
Michael G Backlund
Nicholas A Foley
Patsy Clark
Subhashini Chandrasekharan
P2860
P356
10.1016/J.PROSTAGLANDINS.2008.10.003
P577
2008-11-01T00:00:00Z