Hypoxia-inducible factor 1 is a master regulator of breast cancer metastatic niche formation. - Wikidata - awgldk - TriplyDB

Hypoxia-inducible factor 1 is a master regulator of breast cancer metastatic niche formation.

Hypoxia-inducible factor 1 is a master regulator of breast cancer metastatic niche formation.

http://www.wikidata.org/entity/Q35239845

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Hypoxia-inducible factors mediate coordinated RhoA-ROCK1 expression and signaling in breast cancer cells Hypoxic control of metastasis Overcoming Hypoxia-Mediated Tumor Progression: Combinatorial Approaches Targeting pH Regulation, Angiogenesis and Immune Dysfunction Tumour progression and metastasis The Effect of Hypoxia on Mesenchymal Stem Cell Biology Bone metastases: When and how lung cancer interacts with bone Role of hypoxia-inducible factors in breast cancer metastasis Peptide Hydrogels - Versatile Matrices for 3D Cell Culture in Cancer Medicine Cancer-stromal cell interactions mediated by hypoxia-inducible factors promote angiogenesis, lymphangiogenesis, and metastasis Hypoxia-inducible factors in physiology and medicine Exosomes secreted under hypoxia enhance invasiveness and stemness of prostate cancer cells by targeting adherens junction molecules Implications of Hypoxia in Breast Cancer Metastasis to Bone Hypoxia-inducible factor 1 and breast cancer metastasis The LINK-A lncRNA activates normoxic HIF1α signalling in triple-negative breast cancer Inflammation and Its Correlates in Regenerative Wound Healing: An Alternate Perspective Hypoxia-inducing factors as master regulators of stemness properties and altered metabolism of cancer- and metastasis-initiating cells Formation and role of exosomes in cancer.Hypoxia-inducible factor-dependent signaling between triple-negative breast cancer cells and mesenchymal stem cells promotes macrophage recruitment.Hypoxia-inducible factors and RAB22A mediate formation of microvesicles that stimulate breast cancer invasion and metastasis.mTORC1 drives HIF-1α and VEGF-A signalling via multiple mechanisms involving 4E-BP1, S6K1 and STAT3 SHARP1 suppresses breast cancer metastasis by promoting degradation of hypoxia-inducible factors.LOXL2 in epithelial cell plasticity and tumor progression.The pre-metastatic niche: finding common ground.Hypoxia as a biomarker for radioresistant cancer stem cells.Structural ECM components in the premetastatic and metastatic niche.P2Y2R activation by nucleotides released from the highly metastatic breast cancer cell MDA-MB-231 contributes to pre-metastatic niche formation by mediating lysyl oxidase secretion, collagen crosslinking, and monocyte recruitment.Switching of pyruvate kinase isoform L to M2 promotes metabolic reprogramming in hepatocarcinogenesis.Hypoxia and the extracellular matrix: drivers of tumour metastasis Breast tumor kinase (Brk/PTK6) is a mediator of hypoxia-associated breast cancer progression.HIF transcription factors, inflammation, and immunity.The Warburg effect: evolving interpretations of an established concept HIF-inducible miR-191 promotes migration in breast cancer through complex regulation of TGFβ-signaling in hypoxic microenvironment Lysyl oxidase-like 2 represses Notch1 expression in the skin to promote squamous cell carcinoma progression.HEXIM1 down-regulates hypoxia-inducible factor-1α protein stability.Expression of HIF-1α and Markers of Angiogenesis Are Not Significantly Different in Triple Negative Breast Cancer Compared to Other Breast Cancer Molecular Subtypes: Implications for Future Therapy Hypoxia alters the recruitment of tropomyosins into the actin stress fibres of neuroblastoma cells.Four-and-a-half LIM domain proteins inhibit transactivation by hypoxia-inducible factor 1 Lysyl Oxidase as a Serum Biomarker of Liver Fibrosis in Patients with Severe Obesity and Obstructive Sleep Apnea.Mitophagy defects arising from BNip3 loss promote mammary tumor progression to metastasis Hypoxia-inducible factors: mediators of cancer progression and targets for cancer therapy.

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P2860

Hypoxia-inducible factor 1 is a master regulator of breast cancer metastatic niche formation.

http://www.wikidata.org/entity/Q35239845

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2011年論文

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Hypoxia-inducible factor 1 is ...... er metastatic niche formation.

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Hypoxia-inducible factor 1 is ...... er metastatic niche formation.

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Hypoxia-inducible factor 1 is ...... er metastatic niche formation.

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Hypoxia-inducible factor 1 is ...... er metastatic niche formation.

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PNAS.1113483108

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Proceedings of the National Academy of Sciences of the United States of America

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Hypoxia-inducible factor 1 is ...... er metastatic niche formation.

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Carmen Chak-Lui Wong

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Chun-Ming Wong

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Daniele M Gilkes

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Denis Wirtz

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Hong Wei

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Huafeng Zhang

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Irene Oi-Lin Ng

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Jasper Chen

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Pallavi Chaturvedi

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Stephanie I Fraley

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P2860

Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension

VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche

Hypoxia-induced lysyl oxidase is a critical mediator of bone marrow cell recruitment to form the premetastatic niche

Matrix crosslinking forces tumor progression by enhancing integrin signaling

Levels of hypoxia-inducible factor-1alpha independently predict prognosis in patients with lymph node negative breast carcinoma

Lysyl oxidases: a novel multifunctional amine oxidase family

Lysyl oxidase is essential for hypoxia-induced metastasis

A perspective on cancer cell metastasis

Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeutics

The lysyl oxidase inhibitor, beta-aminopropionitrile, diminishes the metastatic colonization potential of circulating breast cancer cells

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108

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Gregg L. Semenza

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51631748

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