Superoxide dismutase 1 (SOD1) is a target for a small molecule identified in a screen for inhibitors of the growth of lung adenocarcinoma cell lines. - Wikidata - awgldk - TriplyDB

Superoxide dismutase 1 (SOD1) is a target for a small molecule identified in a screen for inhibitors of the growth of lung adenocarcinoma cell lines.

Superoxide dismutase 1 (SOD1) is a target for a small molecule identified in a screen for inhibitors of the growth of lung adenocarcinoma cell lines.

http://www.wikidata.org/entity/Q35239892

about

Oxidative stress and adult neurogenesis--effects of radiation and superoxide dismutase deficiency Superoxide dismutase 1 acts as a nuclear transcription factor to regulate oxidative stress resistance.The copper chelator ATN-224 induces peroxynitrite-dependent cell death in hematological malignancies RETRACTED: Gene-gene interaction network analysis of ovarian cancer using TCGA data Sclareol inhibits cell proliferation and sensitizes cells to the antiproliferative effect of bortezomib via upregulating the tumor suppressor caveolin-1 in cervical cancer cells.SOD1, an unexpected novel target for cancer therapy A high-content biosensor-based screen identifies cell-permeable activators and inhibitors of EGFR function: implications in drug discovery.Protein interaction discovery using parallel analysis of translated ORFs (PLATO)Discovery of protein interactions using parallel analysis of translated ORFs (PLATO).Mitochondrial sirtuins and their relationships with metabolic disease and cancer.The superoxide dismutase 1 3'UTR maintains high expression of the SOD1 gene in cancer cells: The involvement of the RNA-binding protein AUF-1.Targeting SOD1 induces synthetic lethal killing in BLM- and CHEK2-deficient colorectal cancer cells.Targeting Tyrosine Kinase Inhibitor-Resistant Non-Small Cell Lung Cancer by Inducing Epidermal Growth Factor Receptor Degradation via Methionine 790 Oxidation Glutathione biosynthesis is a metabolic vulnerability in PI(3)K/Akt-driven breast cancer.Is SOD1 loss of function involved in amyotrophic lateral sclerosis?Microarray analysis of differentially-expressed genes and linker genes associated with the molecular mechanism of colorectal cancer.Targeting SOD1 reduces experimental non–small-cell lung cancer SOD2 to SOD1 switch in breast cancer.Manganese superoxide dismutase in cancer prevention.The synthetic lethal killing of RAD54B-deficient colorectal cancer cells by PARP1 inhibition is enhanced with SOD1 inhibition.Redox balance- and radiation-mediated alteration in hippocampal neurogenesis.Expanding roles of superoxide dismutases in cell regulation and cancer Agents in the preclinical development stage for non-small cell lung cancer.CancerResource--updated database of cancer-relevant proteins, mutations and interacting drugs.Unraveling new functions of superoxide dismutase using yeast model system: Beyond its conventional role in superoxide radical scavenging.Proteomics and phosphoproteomics provide insights into the mechanism of action of a novel pyrazolo[3,4-d]pyrimidine Src inhibitor in human osteosarcoma.High content analysis in amyotrophic lateral sclerosis.A HIERARCHICAL BAYESIAN MODEL FOR INFERENCE OF COPY NUMBER VARIANTS AND THEIR ASSOCIATION TO GENE EXPRESSION.Chemical & RNAi screening at MSKCC: a collaborative platform to discover & repurpose drugs to fight disease.Redox regulation of cysteine-dependent enzymes in neurodegeneration.Selenite-mediated production of superoxide radical anions in A549 cancer cells is accompanied by a selective increase in SOD1 concentration, enhanced apoptosis and Se-Cu bonding.Inhibition of Akt/mTOR attenuates age-related changes in mesenchymal stem cells.Novel targets for sensitizing breast cancer cells to TRAIL-induced apoptosis with siRNA delivery.Convergence of miR-143 overexpression, oxidative stress and cell death in HCT116 human colon cancer cells.Emerging therapeutic potential of graviola and its constituents in cancers.Disrupting SOD1 activity inhibits cell growth and enhances lipid accumulation in nasopharyngeal carcinoma.Polarizable molecular mechanics studies of Cu(I)/Zn(II) superoxide dismutase: Bimetallic binding site and structured waters

P2860

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P2860

Superoxide dismutase 1 (SOD1) is a target for a small molecule identified in a screen for inhibitors of the growth of lung adenocarcinoma cell lines.

http://www.wikidata.org/entity/Q35239892

description

2011 nî lūn-bûn

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2011 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

Superoxide dismutase 1 (SOD1) ...... ung adenocarcinoma cell lines.

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Superoxide dismutase 1 (SOD1) ...... ung adenocarcinoma cell lines.

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type

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Superoxide dismutase 1 (SOD1) ...... ung adenocarcinoma cell lines.

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Superoxide dismutase 1 (SOD1) ...... ung adenocarcinoma cell lines.

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Superoxide dismutase 1 (SOD1) ...... ung adenocarcinoma cell lines.

@ast

Superoxide dismutase 1 (SOD1) ...... ung adenocarcinoma cell lines.

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PNAS.1113554108

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Proceedings of the National Academy of Sciences of the United States of America

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Superoxide dismutase 1 (SOD1) ...... ung adenocarcinoma cell lines.

@en

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Chris Sander

http://www.w3.org/2001/XMLSchema#string

David Shum

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Erik Larsson

http://www.w3.org/2001/XMLSchema#string

Guangli Yang

http://www.w3.org/2001/XMLSchema#string

Hakim Djaballah

http://www.w3.org/2001/XMLSchema#string

Romel Somwar

http://www.w3.org/2001/XMLSchema#string

William W Lockwood

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P2860

Regulation of the copper chaperone CCS by XIAP-mediated ubiquitination

RETRACTED: Selective killing of cancer cells by a small molecule targeting the stress response to ROS

Somatic mutations affect key pathways in lung adenocarcinoma

PID: the Pathway Interaction Database

Structures of Lung Cancer-Derived EGFR Mutants and Inhibitor Complexes: Mechanism of Activation and Insights into Differential Inhibitor Sensitivity

Cancer statistics, 2008

Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis

Superoxide dismutase. An enzymic function for erythrocuprein (hemocuprein)

Human Protein Reference Database--2009 update

Reactome knowledgebase of human biological pathways and processes

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39

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108

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Hediye Erdjument-Bromage

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Ouathek Ouerfelli

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