Naturally selected hepatitis C virus polymorphisms confer broad neutralizing antibody resistance. - Wikidata - awgldk - TriplyDB

Naturally selected hepatitis C virus polymorphisms confer broad neutralizing antibody resistance.

Naturally selected hepatitis C virus polymorphisms confer broad neutralizing antibody resistance.

http://www.wikidata.org/entity/Q35242585

about

A Hepatitis C Virus Envelope Polymorphism Confers Resistance to Neutralization by Polyclonal Sera and Broadly Neutralizing Monoclonal Antibodies Broadly neutralizing antibodies with few somatic mutations and hepatitis C virus clearance The genetics of hepatitis C virus underlie its ability to escape humoral immunity Applying antibody-sensitive hypervariable region 1-deleted hepatitis C virus to the study of escape pathways of neutralizing human monoclonal antibody AR5A.Extra-epitopic hepatitis C virus polymorphisms confer resistance to broadly neutralizing antibodies by modulating binding to scavenger receptor B1 Antibodies to an interfering epitope in hepatitis C virus E2 can mask vaccine-induced neutralizing activity CD4+ T-cell recovery with suppressive ART-induced rapid sequence evolution in hepatitis C virus envelope but not NS3.Broad Anti-Hepatitis C Virus (HCV) Antibody Responses Are Associated with Improved Clinical Disease Parameters in Chronic HCV Infection Global mapping of antibody recognition of the hepatitis C virus E2 glycoprotein: Implications for vaccine design.RNA Viruses and RNAi: Quasispecies Implications for Viral Escape Role of Conserved E2 Residue W420 in Receptor Binding and Hepatitis C Virus Infection.A Diverse Panel of Hepatitis C Virus Glycoproteins for Use in Vaccine Research Reveals Extremes of Monoclonal Antibody Neutralization Resistance.Viral evasion and challenges of hepatitis C virus vaccine development.Designing an HCV vaccine: a unique convergence of prevention and therapy?Limited naturally occurring escape in broadly neutralizing antibody epitopes in hepatitis C glycoprotein E2 and constrained sequence usage in acute infection.Novel functional hepatitis C virus glycoprotein isolates identified using an optimized viral pseudotype entry assay.Affinity maturation of a broadly neutralizing human monoclonal antibody that prevents acute hepatitis C virus infection in mice.Hepatitis C virus resistance to broadly neutralizing antibodies measured using replication-competent virus and pseudoparticles.Innate and Adaptive Immune Responses in Chronic HCV Infection.Synergistic anti-HCV broadly neutralizing human monoclonal antibodies with independent mechanisms.Probing the antigenicity of hepatitis C virus envelope glycoprotein complex by high-throughput mutagenesis.Immunopathogenesis of Hepatitis C Virus Infection.Conformational Flexibility in the CD81-Binding Site of the Hepatitis C Virus Glycoprotein E2.Predicting the Effectiveness of Hepatitis C Virus Neutralizing Antibodies by Bioinformatic Analysis of Conserved Epitope Residues Using Public Sequence Data.Defining Breadth of Hepatitis C Virus Neutralization Hepatitis C Virus Envelope Glycoproteins: A Balancing Act of Order and Disorder Hypervariable Region 1 in Envelope Protein 2 of Hepatitis C Virus: A Linchpin in Neutralizing Antibody Evasion and Viral Entry

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P2860

Naturally selected hepatitis C virus polymorphisms confer broad neutralizing antibody resistance.

http://www.wikidata.org/entity/Q35242585

description

2014 nî lūn-bûn

@nan

2014 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2014年の論文

@ja

2014年論文

@yue

2014年論文

@zh-hant

2014年論文

@zh-hk

2014年論文

@zh-mo

2014年論文

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2014年论文

@wuu

name

Naturally selected hepatitis C ...... tralizing antibody resistance.

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Naturally selected hepatitis C ...... tralizing antibody resistance.

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Naturally selected hepatitis C ...... tralizing antibody resistance.

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Naturally selected hepatitis C ...... tralizing antibody resistance.

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Naturally selected hepatitis C ...... tralizing antibody resistance.

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Naturally selected hepatitis C ...... tralizing antibody resistance.

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Journal of Clinical Investigation

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Naturally selected hepatitis C ...... tralizing antibody resistance.

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P2093

Anna E Snider

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Justin R Bailey

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Lisa N Wasilewski

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Steven K H Foung

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William O Osburn

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Zhenyong Keck

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P2860

Infectious hepatitis C virus pseudo-particles containing functional E1-E2 envelope protein complexes

Human monoclonal antibodies that inhibit binding of hepatitis C virus E2 protein to CD81 and recognize conserved conformational epitopes

Hepatitis C virus glycoproteins mediate pH-dependent cell entry of pseudotyped retroviral particles

Human combinatorial libraries yield rare antibodies that broadly neutralize hepatitis C virus

Identification of a Broadly Cross-Reacting and Neutralizing Human Monoclonal Antibody Directed against the Hepatitis C Virus E2 Protein

Development of JFH1-based cell culture systems for hepatitis C virus genotype 4a and evidence for cross-genotype neutralization

Neutralizing antibodies against hepatitis C virus and the emergence of neutralization escape mutant viruses

A Point Mutation Leading to Hepatitis C Virus Escape from Neutralization by a Monoclonal Antibody to a Conserved Conformational Epitope

Mutations in Hepatitis C Virus E2 Located outside the CD81 Binding Sites Lead to Escape from Broadly Neutralizing Antibodies but Compromise Virus Infectivity

Identification and Characterization of Broadly Neutralizing Human Monoclonal Antibodies Directed against the E2 Envelope Glycoprotein of Hepatitis C Virus

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10.1172/JCI78794

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2014-12-15T00:00:00Z

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