Targeted disruption of the CCR5 gene in human hematopoietic stem cells stimulated by peptide nucleic acids - Wikidata - awgldk - TriplyDB

Targeted disruption of the CCR5 gene in human hematopoietic stem cells stimulated by peptide nucleic acids

Targeted disruption of the CCR5 gene in human hematopoietic stem cells stimulated by peptide nucleic acids

http://www.wikidata.org/entity/Q35244141

about

Targeted gene disruption to cure HIV In vivo correction of anaemia in β-thalassemic mice by γPNA-mediated gene editing with nanoparticle delivery Improved bioactivity of G-rich triplex-forming oligonucleotides containing modified guanine bases.Transmembrane protein aptamers that inhibit CCR5 expression and HIV coreceptor function Efficient ablation of genes in human hematopoietic stem and effector cells using CRISPR/Cas9 Single-stranded γPNAs for in vivo site-specific genome editing via Watson-Crick recognition.RNA interference approaches for treatment of HIV-1 infection Nanoparticles that deliver triplex-forming peptide nucleic acid molecules correct F508del CFTR in airway epithelium The therapeutic application of CRISPR/Cas9 technologies for HIV.Local delivery of gene-modifying triplex-forming molecules to the epidermis.Triplex-forming peptide nucleic acids induce heritable elevations in gamma-globin expression in hematopoietic progenitor cells.Systemic delivery of triplex-forming PNA and donor DNA by nanoparticles mediates site-specific genome editing of human hematopoietic cells in vivo.Nanoparticle for delivery of antisense γPNA oligomers targeting CCR5 Site-specific Genome Editing in PBMCs With PLGA Nanoparticle-delivered PNAs Confers HIV-1 Resistance in Humanized Mice.Bacterial cellular engineering by genome editing and gene silencing Eliminating the HIV reservoir.Personalized gene therapy locks out HIV, paving the way to control virus without antiretroviral drugs.Cell-based gene therapy against HIV.Nanotechnology for delivery of peptide nucleic acids (PNAs)Design of Tail-Clamp Peptide Nucleic Acid Tethered with Azobenzene Linker for Sequence-Specific Detection of Homopurine DNA.[A new toolbox for genome editing].Peptide Nucleic Acids as a Tool for Site-Specific Gene Editing.Therapeutic Peptide Nucleic Acids: Principles, Limitations, and Opportunities.

P2860

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P2860

Targeted disruption of the CCR5 gene in human hematopoietic stem cells stimulated by peptide nucleic acids

http://www.wikidata.org/entity/Q35244141

description

2011 nî lūn-bûn

@nan

2011 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի սեպտեմբերին հրատարակված գիտական հոդված

@hy

2011年の論文

@ja

2011年論文

@yue

2011年論文

@zh-hant

2011年論文

@zh-hk

2011年論文

@zh-mo

2011年論文

@zh-tw

2011年论文

@wuu

name

Targeted disruption of the CCR ...... lated by peptide nucleic acids

@ast

Targeted disruption of the CCR ...... lated by peptide nucleic acids

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type

label

Targeted disruption of the CCR ...... lated by peptide nucleic acids

@ast

Targeted disruption of the CCR ...... lated by peptide nucleic acids

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prefLabel

Targeted disruption of the CCR ...... lated by peptide nucleic acids

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Targeted disruption of the CCR ...... lated by peptide nucleic acids

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P356

J.CHEMBIOL.2011.07.010

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Chemistry and Biology

P1476

Targeted disruption of the CCR ...... lated by peptide nucleic acids

@en

P2093

Dale L Greiner

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Erica B Schleifman

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Faye A Rogers

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Jacob del Campo

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Jean Leif

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Leonard D Shultz

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Peter M Glazer

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Pradeep Uchil

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Priti Kumar

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Ranjit Bindra

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P2860

Dengue virus infection and virus-specific HLA-A2 restricted immune responses in humanized NOD-scid IL2rgammanull mice

T cell-specific siRNA delivery suppresses HIV-1 infection in humanized mice

Correction of a splice-site mutation in the beta-globin gene stimulated by triplex-forming peptide nucleic acids

CXCR4 and CCR5 shRNA transgenic CD34+ cell derived macrophages are functionally normal and resist HIV-1 infection

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

Resistance to HIV-1 infection in caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene

Homozygous defect in HIV-1 coreceptor accounts for resistance of some multiply-exposed individuals to HIV-1 infection

Long-term control of HIV by CCR5 Delta32/Delta32 stem-cell transplantation

Establishment of HIV-1 resistance in CD4+ T cells by genome editing using zinc-finger nucleases

Triplex-induced recombination in human cell-free extracts. Dependence on XPA and HsRad51.

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10.1016/J.CHEMBIOL.2011.07.010

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9

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