Crystal structure of the FLT3 kinase domain bound to the inhibitor Quizartinib (AC220).
about
Discovery of a Diaminopyrimidine FLT3 Inhibitor Active against Acute Myeloid Leukemia.Discovery of Novel Antiangiogenic Marine Natural Product Scaffolds.The MERTK/FLT3 inhibitor MRX-2843 overcomes resistance-conferring FLT3 mutations in acute myeloid leukemia.Approved and Experimental Small-Molecule Oncology Kinase Inhibitor Drugs: A Mid-2016 Overview.Discovery of a Highly Potent and Selective Indenoindolone Type 1 Pan-FLT3 Inhibitor.Phase 1 study of quizartinib in combination with induction and consolidation chemotherapy in patients with newly diagnosed acute myeloid leukemia.Targeted therapies in Acute Myeloid Leukemia: a focus on FLT-3 inhibitors and ABT199.The molecular mechanism behind resistance of the kinase FLT3 to the inhibitor quizartinib.MZH29 is a novel potent inhibitor that overcomes drug resistance FLT3 mutations in acute myeloid leukemia.Heat shock protein 90 inhibitors overcome the resistance to Fms-like tyrosine kinase 3 inhibitors in acute myeloid leukemia
P2860
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P2860
Crystal structure of the FLT3 kinase domain bound to the inhibitor Quizartinib (AC220).
description
2015 nî lūn-bûn
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2015 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
Crystal structure of the FLT3 kinase domain bound to the inhibitor Quizartinib (AC220).
@ast
Crystal structure of the FLT3 kinase domain bound to the inhibitor Quizartinib (AC220).
@en
type
label
Crystal structure of the FLT3 kinase domain bound to the inhibitor Quizartinib (AC220).
@ast
Crystal structure of the FLT3 kinase domain bound to the inhibitor Quizartinib (AC220).
@en
prefLabel
Crystal structure of the FLT3 kinase domain bound to the inhibitor Quizartinib (AC220).
@ast
Crystal structure of the FLT3 kinase domain bound to the inhibitor Quizartinib (AC220).
@en
P2093
P2860
P1433
P1476
Crystal structure of the FLT3 kinase domain bound to the inhibitor Quizartinib (AC220).
@en
P2093
Eric Fujimura
John Kuriyan
Julie A Zorn
P2860
P304
P356
10.1371/JOURNAL.PONE.0121177
P407
P50
P577
2015-04-02T00:00:00Z