Does impairment of energy metabolism result in excitotoxic neuronal death in neurodegenerative illnesses?
about
ALS-associated mutant SOD1G93A causes mitochondrial vacuolation by expansion of the intermembrane space and by involvement of SOD1 aggregation and peroxisomesNeuroprotective and symptomatic effects of targeting group III mGlu receptors in neurodegenerative diseaseThe widespread role of non-enzymatic reactions in cellular metabolismGlutamate in neurologic diseasesSirolimus, but not the structurally related RAD (everolimus), enhances the negative effects of cyclosporine on mitochondrial metabolism in the rat brainPresynaptic function is altered in snake K+-depolarized motor nerve terminals containing compromised mitochondriaRole for dopamine in malonate-induced damage in vivo in striatum and in vitro in mesencephalic culturesS. choloroleuca, S. mirzayanii and S. santolinifolia protect PC12 cells from H(2)O (2)-induced apoptosis by blocking the intrinsic pathwayHdhQ111 Mice Exhibit Tissue Specific Metabolite Profiles that Include Striatal Lipid AccumulationCortical microhemorrhages cause local inflammation but do not trigger widespread dendrite degenerationGenistein improves 3-NPA-induced memory impairment in ovariectomized rats: impact of its antioxidant, anti-inflammatory and acetylcholinesterase modulatory properties.Mouse models of Huntington's disease and methodological considerations for therapeutic trials.Phosphorylation of the translation initiation factor eIF2alpha increases BACE1 levels and promotes amyloidogenesis.Drug refractory epilepsy in brain damage: effect of dextromethorphan on EEG in four patients.Acquired mitochondrial impairment as a cause of optic nerve disease.Creatine kinase B-driven energy transfer in the brain is important for habituation and spatial learning behaviour, mossy fibre field size and determination of seizure susceptibility.Neuroprotection by estrogen via extracellular signal-regulated kinase against quinolinic acid-induced cell death in the rat hippocampus.Astroglial trophic support and neuronal cell death: influence of cellular energy level on type of cell death induced by mitochondrial toxin in cultured rat cortical neurons.Insights into the effects of alpha-synuclein expression and proteasome inhibition on glutathione metabolism through a dynamic in silico model of Parkinson's disease: validation by cell culture data.Advanced In Vivo Heteronuclear MRS Approaches for Studying Brain Bioenergetics Driven by MitochondriaHydrogen in drinking water reduces dopaminergic neuronal loss in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease.Complexity and heterogeneity: what drives the ever-changing brain in Huntington's disease?A disruption in iron-sulfur center biogenesis via inhibition of mitochondrial dithiol glutaredoxin 2 may contribute to mitochondrial and cellular iron dysregulation in mammalian glutathione-depleted dopaminergic cells: implications for Parkinson's dMitochondrial DNA mutations and mitochondrial dysfunction in epilepsy.Neurotoxic mechanisms of degeneration in motor neuron diseases.Selective neuronal vulnerability to oxidative stress in the brain.Identification and localization of huntingtin in brain and human lymphoblastoid cell lines with anti-fusion protein antibodiesDifferential vulnerability of neurons in Huntington's disease: the role of cell type-specific features.In vivo oxygen-17 NMR for imaging brain oxygen metabolism at high fieldBMCP1: a mitochondrial uncoupling protein in neurons which regulates mitochondrial function and oxidant production.Chronic mitochondrial energy impairment produces selective striatal degeneration and abnormal choreiform movements in primates.Asiatic acid, a pentacyclic triterpene from Centella asiatica, is neuroprotective in a mouse model of focal cerebral ischemia.Role of oxidative stress and antioxidants in neurodegenerative diseases.Development of (17)O NMR approach for fast imaging of cerebral metabolic rate of oxygen in rat brain at high fieldA combination of ascorbic acid and α-tocopherol to test the effectiveness and safety in the fragile X syndrome: study protocol for a phase II, randomized, placebo-controlled trialReactive oxygen/nitrogen species and their functional correlations in neurodegenerative diseases.Inhibition of neuronal cell mitochondrial complex I with rotenone increases lipid β-oxidation, supporting acetyl-coenzyme A levels.Oxidative damage and mitochondrial decay in aging.Melatonin combats molecular terrorism at the mitochondrial level.Development of lipophilic cations as therapies for disorders due to mitochondrial dysfunction.
P2860
Q24792140-47D7DAF8-B654-40A2-8906-6C6EDD749C65Q26995351-A857C2CC-35DA-47BD-B9D1-EE5ACE30E864Q26996495-30075D64-271F-483D-9B82-E9DDCC54B422Q28259105-7DFB0D5B-DEFA-4BA7-BD51-EC2CAD99A20CQ28343921-E154F93A-31D6-4FD3-AA1B-3976481AE9F7Q28361761-433D0975-E7E0-4F9D-8784-675109E6B7DAQ28374491-CCC3E76B-93B1-4580-B3EE-17A8F130BAEFQ28386358-EBC600F0-7E28-400A-B3C3-E88C1C209C82Q28386493-0143B2C0-AB36-417A-AD6A-4FAB934ACC34Q28743689-DCB2514B-915C-4FD5-A6FD-A63C3F56B268Q30418168-7452C4E1-8815-4FEC-B5FB-42A848A065E2Q30481208-3DE2D2BF-D126-4EA3-B00B-870DCECD5A62Q30486959-BB92EFF7-736D-4F2D-B867-456D4A5FA4CEQ30495774-8088C1D4-4F5A-4969-8B02-059A39774F7AQ30502654-772D03A3-CC46-4F8D-87C6-0D4C6AD065E6Q30697610-7EE99250-ADA0-4162-926E-A8F25AAD2B08Q31900282-D4262861-5346-4591-A50B-556FBF1BA5B0Q33180865-86322F73-AF7F-4BDF-ABF9-513C81F86DF6Q33365370-44832D79-5F52-4FE6-BE08-0E3D4604645DQ33374303-07975D3D-0A2A-4115-8110-508FABA9549AQ33507513-D2E38F25-C933-4972-8B74-33F7C65CB41AQ33619310-1E0954CA-7A47-46DC-B3C9-7DA4D8227A6EQ33644307-5332F8A7-EB03-4C4B-AE13-35C7C729B07BQ33710791-6D0935FF-76DA-4D57-A989-F85A37524A90Q33719819-7429B68C-5833-47A1-A2AB-C66D0D8BCE42Q33868370-4292FA64-6CD6-4F8C-B781-4874BDD0BE4AQ33920421-52C160E4-DE9C-4B25-ACAA-65FED3BE7260Q33931283-F4C152C8-1B35-4752-89EF-F7D23F5EDC5EQ34057751-EB1EED5A-6113-42D4-B814-75D96ABD89B9Q34101070-30CA61FF-CE3C-4A75-A75C-6D1AC3ED2A47Q34103541-CA0D67DF-D332-43C1-92A1-5AE626B2E32BQ34139006-00609907-5442-4544-891E-4AA28AD21762Q34154938-A80DF167-8FA0-4D3C-9F44-F4CEE497656DQ34192127-0A44E4D5-DF3F-4C9C-8192-624DBAC54275Q34207747-1228F8DA-91AB-46FC-8DB0-8443973FC732Q34243986-3991EE10-5DFD-4811-AEC6-E72E0E4E7951Q34245004-A67DDB06-82B2-4EF8-B4BA-71E9A27E47DCQ34326443-B1F588E9-70D3-42E3-BFA1-A8FB24192916Q34359618-66FF2AB6-F272-4D04-8DA1-4FA0BAD4105DQ34452604-ACEF9AF1-D817-46EC-BED2-B7AE6D313C4B
P2860
Does impairment of energy metabolism result in excitotoxic neuronal death in neurodegenerative illnesses?
description
1992 nî lūn-bûn
@nan
1992 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1992 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1992年の論文
@ja
1992年論文
@yue
1992年論文
@zh-hant
1992年論文
@zh-hk
1992年論文
@zh-mo
1992年論文
@zh-tw
1992年论文
@wuu
name
Does impairment of energy meta ...... n neurodegenerative illnesses?
@ast
Does impairment of energy meta ...... n neurodegenerative illnesses?
@en
type
label
Does impairment of energy meta ...... n neurodegenerative illnesses?
@ast
Does impairment of energy meta ...... n neurodegenerative illnesses?
@en
prefLabel
Does impairment of energy meta ...... n neurodegenerative illnesses?
@ast
Does impairment of energy meta ...... n neurodegenerative illnesses?
@en
P2860
P356
P1433
P1476
Does impairment of energy meta ...... n neurodegenerative illnesses?
@en
P2093
P2860
P304
P356
10.1002/ANA.410310202
P577
1992-02-01T00:00:00Z