Glioma cells with the IDH1 mutation modulate metabolic fractional flux through pyruvate carboxylase - Wikidata - awgldk - TriplyDB

Glioma cells with the IDH1 mutation modulate metabolic fractional flux through pyruvate carboxylase

Glioma cells with the IDH1 mutation modulate metabolic fractional flux through pyruvate carboxylase

http://www.wikidata.org/entity/Q35268977

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Metabolic consequences of oncogenic IDH mutations Magnetic Resonance (MR) Metabolic Imaging in Glioma.MR Molecular Imaging of Brain Cancer Metabolism Using Hyperpolarized 13C Magnetic Resonance Spectroscopy.Pyruvate Carboxylase Is Up-Regulated in Breast Cancer and Essential to Support Growth and Invasion of MDA-MB-231 Cells Pyruvate carboxylation enables growth of SDH-deficient cells by supporting aspartate biosynthesis.Extreme Vulnerability of IDH1 Mutant Cancers to NAD+ Depletion.IDH1 mutation detection by droplet digital PCR in glioma.Succinyl-proteome profiling of a high taxol containing hybrid Taxus species (Taxus × media) revealed involvement of succinylation in multiple metabolic pathways Hyperpolarized (13)C MR imaging detects no lactate production in mutant IDH1 gliomas: Implications for diagnosis and response monitoring.Decreased expression of IDH1-R132H correlates with poor survival in gastrointestinal cancer.Succinyl-proteome profiling of Dendrobium officinale, an important traditional Chinese orchid herb, revealed involvement of succinylation in the glycolysis pathway The BRAF Inhibitor Vemurafenib Activates Mitochondrial Metabolism and Inhibits Hyperpolarized Pyruvate-Lactate Exchange in BRAF-Mutant Human Melanoma Cells.In silico gene expression analysis reveals glycolysis and acetate anaplerosis in IDH1 wild-type glioma and lactate and glutamate anaplerosis in IDH1-mutated glioma IDH1 Mutation Induces Reprogramming of Pyruvate Metabolism.Metabolic reprogramming of pyruvate dehydrogenase is essential for the proliferation of glioma cells expressing mutant IDH1.Hyperpolarized [1-13C] glutamate: a metabolic imaging biomarker of IDH1 mutational status in glioma Cancer cell metabolism: the essential role of the nonessential amino acid, glutamine.Metabolic Reprogramming in Glioma.Exploring cancer metabolism using stable isotope-resolved metabolomics (SIRM).In Vivo Imaging of Glutamine Metabolism to the Oncometabolite 2-Hydroxyglutarate in IDH1/2 Mutant Tumors.Metabolic characterization of isocitrate dehydrogenase (IDH) mutant and IDH wildtype gliomaspheres uncovers cell type-specific vulnerabilities.

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P2860

Glioma cells with the IDH1 mutation modulate metabolic fractional flux through pyruvate carboxylase

http://www.wikidata.org/entity/Q35268977

description

2014 nî lūn-bûn

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2014 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի սեպտեմբերին հրատարակված գիտական հոդված

@hy

2014年の論文

@ja

2014年論文

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2014年論文

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2014年論文

@zh-hk

2014年論文

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2014年論文

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2014年论文

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name

Glioma cells with the IDH1 mut ...... x through pyruvate carboxylase

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Glioma cells with the IDH1 mut ...... x through pyruvate carboxylase

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Glioma cells with the IDH1 mut ...... x through pyruvate carboxylase

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Glioma cells with the IDH1 mut ...... x through pyruvate carboxylase

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Glioma cells with the IDH1 mut ...... x through pyruvate carboxylase

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Glioma cells with the IDH1 mut ...... x through pyruvate carboxylase

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Glioma cells with the IDH1 mut ...... x through pyruvate carboxylase

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Aaron E Robinson

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Joanna J Phillips

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Larry M Cai

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Pia Eriksson

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Russell O Pieper

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Sabrina M Ronen

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P2860

Cancer-associated IDH1 mutations produce 2-hydroxyglutarate

Gene expression profiling reveals molecularly and clinically distinct subtypes of glioblastoma multiforme

Understanding the Warburg effect: the metabolic requirements of cell proliferation

Recent advances in mechanisms regulating glucose oxidation at the level of the pyruvate dehydrogenase complex by PDKs

The somatic genomic landscape of glioblastoma

Beyond aerobic glycolysis: transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis

The key role of anaplerosis and cataplerosis for citric acid cycle function.

Astroglial contribution to brain energy metabolism in humans revealed by 13C nuclear magnetic resonance spectroscopy: elucidation of the dominant pathway for neurotransmitter glutamate repletion and measurement of astrocytic oxidative metabolism

Analysis of the IDH1 codon 132 mutation in brain tumors.

Dichloroacetate effects on glucose and lactate oxidation by neurons and astroglia in vitro and on glucose utilization by brain in vivo

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scholarly article

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Jose L Izquierdo-Garcia

Myriam Chaumeil

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2014-09-22T00:00:00Z

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266028232

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