Absence of SARM1 rescues development and survival of NMNAT2-deficient axons.
about
Traumatic Axonal Injury: Mechanisms and Translational OpportunitiesStem Cell-Derived Immature Human Dorsal Root Ganglia Neurons to Identify Peripheral Neurotoxicants.Upregulation of calpain activity precedes tau phosphorylation and loss of synaptic proteins in Alzheimer's disease brain.NMNAT1 inhibits axon degeneration via blockade of SARM1-mediated NAD+ depletion.SARM1-specific motifs in the TIR domain enable NAD+ loss and regulate injury-induced SARM1 activation.MAPK signaling promotes axonal degeneration by speeding the turnover of the axonal maintenance factor NMNAT2.Axon Self-Destruction: New Links among SARM1, MAPKs, and NAD+ Metabolism.Molecular mechanisms in the initiation phase of Wallerian degeneration.Axon degeneration: context defines distinct pathways.An Atypical SCF-like Ubiquitin Ligase Complex Promotes Wallerian Degeneration through Regulation of Axonal Nmnat2.A Mechanistic Understanding of Axon Degeneration in Chemotherapy-Induced Peripheral Neuropathy.Deletion of Sarm1 gene is neuroprotective in two models of peripheral neuropathy.Sarm1 Deletion, but Not WldS, Confers Lifelong Rescue in a Mouse Model of Severe AxonopathyModulation of nuclear REST by alternative splicing: a potential therapeutic target for Huntington's disease.Avian axons undergo Wallerian degeneration after injury and stress.Transcription factor Pebbled/RREB1 regulates injury-induced axon degeneration.Prevention of vincristine-induced peripheral neuropathy by genetic deletion of SARM1 in mice.The Axon-Myelin Unit in Development and Degenerative Disease
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P2860
Absence of SARM1 rescues development and survival of NMNAT2-deficient axons.
description
2015 nî lūn-bûn
@nan
2015 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2015 թվականի մարտին հրատարակված գիտական հոդված
@hy
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
name
Absence of SARM1 rescues development and survival of NMNAT2-deficient axons.
@ast
Absence of SARM1 rescues development and survival of NMNAT2-deficient axons.
@en
type
label
Absence of SARM1 rescues development and survival of NMNAT2-deficient axons.
@ast
Absence of SARM1 rescues development and survival of NMNAT2-deficient axons.
@en
prefLabel
Absence of SARM1 rescues development and survival of NMNAT2-deficient axons.
@ast
Absence of SARM1 rescues development and survival of NMNAT2-deficient axons.
@en
P2093
P2860
P1433
P1476
Absence of SARM1 rescues development and survival of NMNAT2-deficient axons.
@en
P2093
Isabel Nascimento-Ferreira
Jonathan Gilley
Michael P Coleman
P2860
P304
P356
10.1016/J.CELREP.2015.02.060
P577
2015-03-26T00:00:00Z