Genotypic and functional properties of early infant HIV-1 envelopes
about
Comparative analysis of the fusion efficiency elicited by the envelope glycoprotein V1-V5 regions derived from human immunodeficiency virus type 1 transmitted perinatally.HIV-1 autologous antibody neutralization associates with mother to child transmissionEstimating the timing of mother-to-child transmission of the human immunodeficiency virus type 1 using a viral molecular evolution modelHIV-1 non-macrophage-tropic R5 envelope glycoproteins are not more tropic for entry into primary CD4+ T-cells than envelopes highly adapted for macrophages.Viral determinants of HIV-1 macrophage tropism.Viremic relapse after HIV-1 remission in a perinatally infected childInfection of ectocervical tissue and universal targeting of T-cells mediated by primary non-macrophage-tropic and highly macrophage-tropic HIV-1 R5 envelopes.Independent evolution of macrophage-tropism and increased charge between HIV-1 R5 envelopes present in brain and immune tissue.Neutralizing antibody escape during HIV-1 mother-to-child transmission involves conformational masking of distal epitopes in envelope.The breadth and titer of maternal HIV-1-specific heterologous neutralizing antibodies are not associated with a lower rate of mother-to-child transmission of HIV-1Recombination elevates the effective evolutionary rate and facilitates the establishment of HIV-1 infection in infants after mother-to-child transmission.Postnatally-transmitted HIV-1 Envelope variants have similar neutralization-sensitivity and function to that of nontransmitted breast milk variantsShort communication: HIV type 1 subtype C variants transmitted through the bottleneck of breastfeeding are sensitive to new generation broadly neutralizing antibodies directed against quaternary and CD4-binding site epitopes.Pilot study on the immunogenicity of paired Env immunogens from mother-to-child transmitted HIV-1 isolates.The role of neutralizing antibodies in prevention of HIV-1 infection: what can we learn from the mother-to-child transmission context?Ontogeny of CD4+ T Lymphocytes With Phenotypic Susceptibility to HIV-1 During Exclusive and Nonexclusive Breastfeeding in HIV-1-Exposed Ugandan Infants.Binding of HIV-1 virions to α4β 7 expressing cells and impact of antagonizing α4β 7 on HIV-1 infection of primary CD4+ T cells.Efficiency of bridging-sheet recruitment explains HIV-1 R5 envelope glycoprotein sensitivity to soluble CD4 and macrophage tropism.Maternal Binding and Neutralizing IgG Responses Targeting the C-Terminal Region of the V3 Loop Are Predictive of Reduced Peripartum HIV-1 Transmission RiskInfant transmitted/founder HIV-1 viruses from peripartum transmission are neutralization resistant to paired maternal plasma.
P2860
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P2860
Genotypic and functional properties of early infant HIV-1 envelopes
description
2011 nî lūn-bûn
@nan
2011 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Genotypic and functional properties of early infant HIV-1 envelopes
@ast
Genotypic and functional properties of early infant HIV-1 envelopes
@en
type
label
Genotypic and functional properties of early infant HIV-1 envelopes
@ast
Genotypic and functional properties of early infant HIV-1 envelopes
@en
prefLabel
Genotypic and functional properties of early infant HIV-1 envelopes
@ast
Genotypic and functional properties of early infant HIV-1 envelopes
@en
P2093
P2860
P356
P1433
P1476
Genotypic and functional properties of early infant HIV-1 envelopes
@en
P2093
Frank Brewster
John L Sullivan
Katherine Luzuriaga
Michael Kishko
Mohan Somasundaran
Paul R Clapham
P2860
P2888
P356
10.1186/1742-4690-8-67
P577
2011-08-15T00:00:00Z
P5875
P6179
1001556408