Reprogramming leukemia cells to terminal differentiation and growth arrest by RNA interference of PU.1.
about
PU.1 directly regulates cdk6 gene expression, linking the cell proliferation and differentiation programs in erythroid cellsRandom small interfering RNA library screen identifies siRNAs that induce human erythroleukemia cell differentiation.Mathematical modeling of GATA-switching for regulating the differentiation of hematopoietic stem cell.PU.1 and Haematopoietic Cell Fate: Dosage MattersMybl2, downregulated during colon epithelial cell maturation, is suppressed by miR-365.Spi-1, Fli-1 and Fli-3 (miR-17-92) oncogenes contribute to a single oncogenic network controlling cell proliferation in friend erythroleukemia.MYBL2, a link between proliferation and differentiation in maturing colon epithelial cells.Stat3 promotes the development of erythroleukemia by inducing Pu.1 expression and inhibiting erythroid differentiationThe role of PU.1 and GATA-1 transcription factors during normal and leukemogenic hematopoiesis.PU.1 activation relieves GATA-1-mediated repression of Cebpa and Cbfb during leukemia differentiation.Fli-1 overexpression in erythroleukemic cells promotes erythroid de-differentiation while Spi-1/PU.1 exerts the opposite effect.DNA methylation-mediated silencing of PU.1 in leukemia cells resistant to cell differentiation.Knockdown of PU.1 AS lncRNA inhibits adipogenesis through enhancing PU.1 mRNA translation.Reprogramming of human peripheral blood monocytes to erythroid lineage by blocking of the PU-1 gene expression.
P2860
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P2860
Reprogramming leukemia cells to terminal differentiation and growth arrest by RNA interference of PU.1.
description
2007 nî lūn-bûn
@nan
2007 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Reprogramming leukemia cells t ...... t by RNA interference of PU.1.
@ast
Reprogramming leukemia cells t ...... t by RNA interference of PU.1.
@en
type
label
Reprogramming leukemia cells t ...... t by RNA interference of PU.1.
@ast
Reprogramming leukemia cells t ...... t by RNA interference of PU.1.
@en
prefLabel
Reprogramming leukemia cells t ...... t by RNA interference of PU.1.
@ast
Reprogramming leukemia cells t ...... t by RNA interference of PU.1.
@en
P2860
P1476
Reprogramming leukemia cells t ...... t by RNA interference of PU.1.
@en
P2093
Arthur I Skoultchi
Michael Papetti
P2860
P304
P356
10.1158/1541-7786.MCR-07-0145
P577
2007-10-01T00:00:00Z