The 90-kDa heat-shock protein (Hsp90)-binding immunophilin FKBP51 is a mitochondrial protein that translocates to the nucleus to protect cells against oxidative stress.
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Nuclear localization of the mitochondrial factor HIGD1A during metabolic stressAdipogenesis is under surveillance of Hsp90 and the high molecular weight Immunophilin FKBP51Elucidating novel hepatitis C virus-host interactions using combined mass spectrometry and functional genomics approachesC-terminal domain of SMYD3 serves as a unique HSP90-regulated motif in oncogenesisCommitment of Scaffold Proteins in the Onco-Biology of Human Colorectal Cancer and Liver Metastases after Oxaliplatin-Based ChemotherapyNF-κB transcriptional activity is modulated by FK506-binding proteins FKBP51 and FKBP52: a role for peptidyl-prolyl isomerase activity.Molecular chaperone dysfunction in neurodegenerative diseases and effects of curcumin.DNA damage and transcriptional changes in the gills of mytilus galloprovincialis exposed to nanomolar doses of combined metal salts (Cd, Cu, Hg).Mitochondria-nucleus shuttling FK506-binding protein 51 interacts with TRAF proteins and facilitates the RIG-I-like receptor-mediated expression of type I IFNLithium Chloride Dependent Glycogen Synthase Kinase 3 Inactivation Links Oxidative DNA Damage, Hypertrophy and Senescence in Human Articular Chondrocytes and Reproduces Chondrocyte Phenotype of Obese Osteoarthritis Patients.FKBP51 employs both scaffold and isomerase functions to promote NF-κB activation in melanoma.FK506 binding protein 51 positively regulates melanoma stemness and metastatic potential.Expression and localization of the immunophilin FKBP51 in colorectal carcinomas and primary metastases, and alterations following oxaliplatin-based chemotherapyDynamic mitochondrial-nuclear redistribution of the immunophilin FKBP51 is regulated by the PKA signaling pathway to control gene expression during adipocyte differentiationInhibition of heat shock protein 90 improves pulmonary arteriole remodeling in pulmonary arterial hypertension.The emerging role of large immunophilin FK506 binding protein 51 in cancerRegulation of the glucocorticoid response to stress-related disorders by the Hsp90-binding immunophilin FKBP51.Heat shock proteins in cancer: targeting the 'chaperones'.Hsp90-binding immunophilins as a potential new platform for drug treatment.A review of reagents for fluorescence microscopy of cellular compartments and structures, Part II: reagents for non-vesicular organelles.Biological relevance of Hsp90-binding immunophilins in cancer development and treatment.HSP90AB1: Helping the good and the bad.FKBP51 Null Mice Are Resistant to Diet-Induced Obesity and the PPARγ Agonist Rosiglitazone.Hsp90-binding immunophilin FKBP51 forms complexes with hTERT enhancing telomerase activity.Glycogen Synthase Kinase-3β Inhibition Links Mitochondrial Dysfunction, Extracellular Matrix Remodelling and Terminal Differentiation in Chondrocytes.N-Acetylcysteine affects obesity-related protein expression in 3T3-L1 adipocytes.Sendai virus recruits cellular villin to remodel actin cytoskeleton during fusion with hepatocytes.Over-expression of miR-146b and its regulatory role in intestinal epithelial cell viability, proliferation, and apoptosis in piglets.The prospect of FKBP51 as a drug target.
P2860
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P2860
The 90-kDa heat-shock protein (Hsp90)-binding immunophilin FKBP51 is a mitochondrial protein that translocates to the nucleus to protect cells against oxidative stress.
description
2011 nî lūn-bûn
@nan
2011 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
The 90-kDa heat-shock protein ...... ells against oxidative stress.
@ast
The 90-kDa heat-shock protein ...... ells against oxidative stress.
@en
type
label
The 90-kDa heat-shock protein ...... ells against oxidative stress.
@ast
The 90-kDa heat-shock protein ...... ells against oxidative stress.
@en
prefLabel
The 90-kDa heat-shock protein ...... ells against oxidative stress.
@ast
The 90-kDa heat-shock protein ...... ells against oxidative stress.
@en
P2860
P356
P1476
The 90-kDa heat-shock protein ...... cells against oxidative stress
@en
P2093
Graciela Piwien-Pilipuk
Mariana Lagadari
P2860
P304
30152-30160
P356
10.1074/JBC.M111.256610
P407
P577
2011-07-05T00:00:00Z