Biochemical and pharmacological profile of a potent and selective endothelin B-receptor antagonist, BQ-788.
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Characterization of endothelin receptors in the human umbilical artery and veinEndothelinEndothelin receptors and their antagonistsRole of endothelin in cardiovascular diseaseEndothelin@25 - new agonists, antagonists, inhibitors and emerging research frontiers: IUPHAR Review 12Characterization of the binding of endothelin ETB selective ligands in human and rat heartEndothelin-A and -B receptors, superoxide, and Ca2+ signaling in afferent arteriolesDifferential effects of endothelin on activation of renal mechanosensory nerves: stimulatory in high-sodium diet and inhibitory in low-sodium dietLocal antinociception induced by endothelin-1 in the hairy skin of the rat's backCentral endothelin ET(B) receptors mediate IL-1-dependent fever induced by preformed pyrogenic factor and corticotropin-releasing factor in the ratEndothelin-1 and the periaqueductal gray area of the rat: an autoradiographic and functional pharmacological study.Transcriptional down-regulation of the rabbit pulmonary artery endothelin B receptor during phenotypic modulationSelected contribution: Gender differences in the endothelin-B receptor contribution to basal cutaneous vascular tone in humans.Endothelins and their inhibition in the human skin microcirculation: ET[1-31], a new vasoconstrictor peptide.Endothelin B receptor-mediated increase of cerebral blood flow in experimental pneumococcal meningitis.Endothelin receptor B antagonists decrease glioma cell viability independently of their cognate receptor.Stimuli of sensory-motor nerves terminate arterial contractile effects of endothelin-1 by CGRP and dissociation of ET-1/ET(A)-receptor complexesAutoimmunity and vascular involvement in systemic sclerosis (SSc).Endothelin B receptor contribution to peripheral microvascular function in women with polycystic ovary syndrome.Potentiation by endothelin-1 of cholinergic nerve-mediated contractions in mouse trachea via activation of ETB receptors.Different pressor and bronchoconstrictor properties of human big-endothelin-1, 2 (1-38) and 3 in ketamine/xylazine-anaesthetized guinea-pigs.Block of endothelin-1-induced release of thromboxane A2 from the guinea pig lung and nitric oxide from the rabbit kidney by a selective ETB receptor antagonist, BQ-788Androgens influence microvascular dilation in PCOS through ET-A and ET-B receptorsRole of the endothelin axis and its antagonists in the treatment of cancerNitric oxide limits the eicosanoid-dependent bronchoconstriction and hypotension induced by endothelin-1 in the guinea-pig.Modulation of ET-1-induced contraction of human bronchi by airway epithelium-dependent nitric oxide release via ET(A) receptor activation.Endothelin-1 enhances neutrophil adhesion to human coronary artery endothelial cells: role of ET(A) receptors and platelet-activating factor.Effect of endothelin antagonists, including the novel ET(A) receptor antagonist LBL 031, on endothelin-1 and lipopolysaccharide-induced microvascular leakage in rat airways.Extracellular signal-regulated kinase plays an essential role in endothelin-1-induced homotypic adhesion of human neutrophil granulocytesPressor and pulmonary responses to ET-1(1-31) in guinea-pigs.ET-1-associated vasomotion and vasospasm in lymphatic vessels of the guinea-pig mesentery.Endothelin and endothelial dysfunction.Enzymatic pathways involved in the generation of endothelin-1(1-31) from exogenous big endothelin-1 in the rabbit aorta.Suc-[Glu9,Ala11,15]-endothelin-1 (8-21), IRL 1620, identifies two populations of ET(B) receptors in guinea-pig bronchus.Endothelin-1 stimulates contraction and migration of rat pancreatic stellate cells.An endothelin receptor B antagonist inhibits growth and induces cell death in human melanoma cells in vitro and in vivoEndothelin-1-induced potentiation of human airway smooth muscle proliferation: an ETA receptor-mediated phenomenon.Localization of endothelin ETB receptors on the myenteric plexus of guinea-pig ileum and the receptor-mediated release of acetylcholine.Inhibition by endothelin-1 of cholinergic nerve-mediated acetylcholine release and contraction in sheep isolated tracheaNecessity of dual blockade of endothelin ETA and ETB receptor subtypes for antagonism of endothelin-1-induced contraction in human bronchi.
P2860
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P2860
Biochemical and pharmacological profile of a potent and selective endothelin B-receptor antagonist, BQ-788.
description
1994 nî lūn-bûn
@nan
1994 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
name
Biochemical and pharmacologica ...... B-receptor antagonist, BQ-788.
@ast
Biochemical and pharmacologica ...... B-receptor antagonist, BQ-788.
@en
type
label
Biochemical and pharmacologica ...... B-receptor antagonist, BQ-788.
@ast
Biochemical and pharmacologica ...... B-receptor antagonist, BQ-788.
@en
prefLabel
Biochemical and pharmacologica ...... B-receptor antagonist, BQ-788.
@ast
Biochemical and pharmacologica ...... B-receptor antagonist, BQ-788.
@en
P2093
P2860
P356
P1476
Biochemical and pharmacologica ...... B-receptor antagonist, BQ-788.
@en
P2093
K Ishikawa
T Fukuroda
P2860
P304
P356
10.1073/PNAS.91.11.4892
P407
P577
1994-05-01T00:00:00Z