Deficiency of Prdx6 in lens epithelial cells induces ER stress response-mediated impaired homeostasis and apoptosis.
about
Thioredoxins, glutaredoxins, and peroxiredoxins--molecular mechanisms and health significance: from cofactors to antioxidants to redox signalingTuning of peroxiredoxin catalysis for various physiological rolesLentivirus-mediated inhibition of tumour necrosis factor-α improves motor function associated with PRDX6 in spinal cord contusion ratsSpecificity protein, Sp1-mediated increased expression of Prdx6 as a curcumin-induced antioxidant defense in lens epithelial cells against oxidative stress.Translating cell survival and cell longevity into treatment strategies with SIRT1Curcumin ameliorates high glucose-induced neural tube defects by suppressing cellular stress and apoptosis.Aberrant sumoylation signaling evoked by reactive oxygen species impairs protective function of Prdx6 by destabilization and repression of its transcription.LEDGF gene silencing impairs the tumorigenicity of prostate cancer DU145 cells by abating the expression of Hsp27 and activation of the Akt/ERK signaling pathwayGeneration of novel monoclonal antibodies for the enrichment and characterization of human corneal endothelial cells (hCENC) necessary for the treatment of corneal endothelial blindnessDelivery of a protein transduction domain-mediated Prdx6 protein ameliorates oxidative stress-induced injury in human and mouse neuronal cellsO-glycosylation modulates integrin and FGF signalling by influencing the secretion of basement membrane components.Elevated tropomyosin expression is associated with epithelial-mesenchymal transition of lens epithelial cells.Curcumin abates hypoxia-induced oxidative stress based-ER stress-mediated cell death in mouse hippocampal cells (HT22) by controlling Prdx6 and NF-κB regulation.Sumoylation-deficient Prdx6 gains protective function by amplifying enzymatic activity and stability and escapes oxidative stress-induced aberrant Sumoylation.The impact of thiol peroxidases on redox regulation.The role of Prdx6 in the protection of cells of the crystalline lens from oxidative stress induced by UV exposure.Prdx6 retards senescence and restores trabecular meshwork cell health by regulating reactive oxygen species.Sulforaphane reactivates cellular antioxidant defense by inducing Nrf2/ARE/Prdx6 activity during aging and oxidative stressMyopathy in Marinesco-Sjögren syndrome links endoplasmic reticulum chaperone dysfunction to nuclear envelope pathology.Age-related cataracts: Role of unfolded protein response, Ca2+ mobilization, epigenetic DNA modifications, and loss of Nrf2/Keap1 dependent cytoprotection.Sumoylation-deficient Prdx6 repairs aberrant Sumoylation-mediated Sp1 dysregulation-dependent Prdx6 repression and cell injury in aging and oxidative stress
P2860
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P2860
Deficiency of Prdx6 in lens epithelial cells induces ER stress response-mediated impaired homeostasis and apoptosis.
description
2011 nî lūn-bûn
@nan
2011 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Deficiency of Prdx6 in lens ep ...... red homeostasis and apoptosis.
@ast
Deficiency of Prdx6 in lens ep ...... red homeostasis and apoptosis.
@en
type
label
Deficiency of Prdx6 in lens ep ...... red homeostasis and apoptosis.
@ast
Deficiency of Prdx6 in lens ep ...... red homeostasis and apoptosis.
@en
prefLabel
Deficiency of Prdx6 in lens ep ...... red homeostasis and apoptosis.
@ast
Deficiency of Prdx6 in lens ep ...... red homeostasis and apoptosis.
@en
P2093
P2860
P1476
Deficiency of Prdx6 in lens ep ...... red homeostasis and apoptosis.
@en
P2093
Bhavana Chhunchha
Biju Bhargavan
Dhirendra P Singh
Nigar Fatma
Prerna Singh
T Shinohara
P2860
P304
P356
10.1152/AJPCELL.00061.2011
P577
2011-06-15T00:00:00Z