Human apoE isoforms differentially regulate brain amyloid-β peptide clearance - Wikidata - awgldk - TriplyDB

Human apoE isoforms differentially regulate brain amyloid-β peptide clearance

Human apoE isoforms differentially regulate brain amyloid-β peptide clearance

http://www.wikidata.org/entity/Q35334161

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Interactions of metals and Apolipoprotein E in Alzheimer's disease Galactic cosmic radiation leads to cognitive impairment and increased aβ plaque accumulation in a mouse model of Alzheimer's disease Alzheimer mechanisms and therapeutic strategies Gene transfer of human Apoe isoforms results in differential modulation of amyloid deposition and neurotoxicity in mouse brain Lysosomal sorting of amyloid-β by the SORLA receptor is impaired by a familial Alzheimer's disease mutation Human APOE genotype affects intraneuronal Aβ1-42 accumulation in a lentiviral gene transfer model Genome-environment interactions that modulate aging: powerful targets for drug discovery Synapses and Alzheimer's disease The Rationale for Insulin Therapy in Alzheimer's Disease Apolipoprotein E: from cardiovascular disease to neurodegenerative disorders Genes associated with Alzheimer's disease: an overview and current status The amyloid hypothesis of Alzheimer's disease at 25 years Emerging Link between Alzheimer's Disease and Homeostatic Synaptic Plasticity Tau Protein Hyperphosphorylation and Aggregation in Alzheimer's Disease and Other Tauopathies, and Possible Neuroprotective Strategies The past and the future of Alzheimer's disease CSF biomarkers-a journey toward validated biochemical tests covering the whole spectrum of molecular events Impaired vascular-mediated clearance of brain amyloid beta in Alzheimer's disease: the role, regulation and restoration of LRP1 Dementia of the eye: the role of amyloid beta in retinal degeneration Pathogenic protein seeding in Alzheimer disease and other neurodegenerative disorders Apolipoprotein E and apolipoprotein E receptors: normal biology and roles in Alzheimer disease Common defects of mitochondria and iron in neurodegeneration and diabetes (MIND): a paradigm worth exploring Alzheimer's disease pathologic cascades: who comes first, what drives what Inconsistencies and controversies surrounding the amyloid hypothesis of Alzheimer's disease Cerebrovascular effects of apolipoprotein E: implications for Alzheimer disease Dysregulation of cholesterol balance in the brain: contribution to neurodegenerative diseases Ushering in the study and treatment of preclinical Alzheimer disease Cerebrospinal Fluid Particles in Alzheimer Disease and Parkinson Disease The liver X receptor agonist GW3965 improves recovery from mild repetitive traumatic brain injury in mice partly through apolipoprotein E Disruption of arterial perivascular drainage of amyloid-β from the brains of mice expressing the human APOE ε4 allele The dendritic hypothesis for Alzheimer's disease pathophysiology.Astrocyte Differentiation of Human Pluripotent Stem Cells: New Tools for Neurological Disorder Research Is ApoE ɛ 4 a good biomarker for amyloid pathology in late onset Alzheimer's disease?Genetic variants associated with neurodegenerative Alzheimer disease in natural models ACAT1/SOAT1 as a therapeutic target for Alzheimer's disease Three dimensions of the amyloid hypothesis: time, space and 'wingmen'Stem cell therapy for Alzheimer's disease and related disorders: current status and future perspectives Analyzing dendritic spine pathology in Alzheimer's disease: problems and opportunities Cerebrospinal fluid biomarkers of neurovascular dysfunction in mild dementia and Alzheimer's disease Apolipoprotein E and Alzheimer disease: risk, mechanisms and therapy Orexin signaling regulates both the hippocampal clock and the circadian oscillation of Alzheimer's disease-risk genes Buying time: a rationale for examining the use of circadian rhythm and sleep interventions to delay progression of mild cognitive impairment to Alzheimer's disease

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Human apoE isoforms differentially regulate brain amyloid-β peptide clearance

http://www.wikidata.org/entity/Q35334161

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2011 nî lūn-bûn

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2011 թուականի Յունիսին հրատարակուած գիտական յօդուած

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2011 թվականի հունիսին հրատարակված գիտական հոդված

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2011年の論文

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2011年学术文章

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2011年学术文章

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2011年学术文章

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2011年学术文章

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2011年学术文章

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2011年學術文章

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name

Human apoE isoforms differentially regulate brain amyloid-β peptide clearance

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Human apoE isoforms differentially regulate brain amyloid-β peptide clearance

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type

label

Human apoE isoforms differentially regulate brain amyloid-β peptide clearance

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Human apoE isoforms differentially regulate brain amyloid-β peptide clearance

@en

altLabel

Human apoE Isoforms Differentially Regulate Brain Amyloid- Peptide Clearance

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prefLabel

Human apoE isoforms differentially regulate brain amyloid-β peptide clearance

@ast

Human apoE isoforms differentially regulate brain amyloid-β peptide clearance

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Science Translational Medicine

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Human apoE isoforms differentially regulate brain amyloid-β peptide clearance

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Bruce W Patterson

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Floy R Stewart

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Hong Jiang

http://www.w3.org/2001/XMLSchema#string

Kelly R Bales

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Kwasi G Mawuenyega

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Ronald B DeMattos

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Steven M Paul

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P2860

Human amyloid-beta synthesis and clearance rates as measured in cerebrospinal fluid in vivo

Amyloid-beta dynamics are regulated by orexin and the sleep-wake cycle

11C PiB and structural MRI provide complementary information in imaging of Alzheimer's disease and amnestic mild cognitive impairment

ApoE promotes the proteolytic degradation of Abeta

Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

Protective effect of apolipoprotein E type 2 allele for late onset Alzheimer disease

Isoform-specific binding of apolipoprotein E to beta-amyloid

Multiplexed immunoassay panel identifies novel CSF biomarkers for Alzheimer's disease diagnosis and prognosis

Characterization of the binding of amyloid-beta peptide to cell culture-derived native apolipoprotein E2, E3, and E4 isoforms and to isoforms from human plasma

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10.1126/SCITRANSLMED.3002156

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89

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Carlos Cruchaga

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David M. Holtzman

Joseph M Castellano

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2011-06-01T00:00:00Z

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51454255

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