mTOR links incretin signaling to HIF induction in pancreatic beta cells.
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Use of glucagon-like peptide-1 agonists to improve islet graft performanceGlucose-dependent insulinotropic polypeptide signaling in pancreatic β-cells and adipocytesGLP-1 receptor signalling promotes β-cell glucose metabolism via mTOR-dependent HIF-1α activationHes3 is expressed in the adult pancreatic islet and regulates gene expression, cell growth, and insulin release.Progesterone receptor membrane component 1 is a functional part of the glucagon-like peptide-1 (GLP-1) receptor complex in pancreatic β cells.Upregulation of CREM/ICER suppresses wound endothelial CRE-HIF-1α-VEGF-dependent signaling and impairs angiogenesis in type 2 diabetes.Dipeptidyl peptidase IV inhibition activates CREB and improves islet vascularization through VEGF-A/VEGFR-2 signaling pathway.A novel antioxidant multitarget iron chelator M30 protects hepatocytes against ethanol-induced injuryATF3 mediates inhibitory effects of ethanol on hepatic gluconeogenesis.Hypoxia-inducible factors in cancer stem cells and inflammation.GLP-1 receptor agonists and the thyroid: C-cell effects in mice are mediated via the GLP-1 receptor and not associated with RET activation.The cannabinoid CB1 receptor and mTORC1 signalling pathways interact to modulate glucose homeostasis in mice.CRFR1 activation protects against cytokine-induced β-cell death.Profile of Marc R. Montminy.Liraglutide is neurotrophic and neuroprotective in neuronal cultures and mitigates mild traumatic brain injury in mice.Dipeptidyl peptidase 4 inhibition may facilitate healing of chronic foot ulcers in patients with type 2 diabetes.Rapamycin Blocks Induction of the Thermogenic Program in White Adipose Tissue.SAD-A potentiates glucose-stimulated insulin secretion as a mediator of glucagon-like peptide 1 response in pancreatic β cells.SAD-A kinase controls islet β-cell size and function as a mediator of mTORC1 signaling.The minimal promoter region of the dense-core vesicle protein IA-2: transcriptional regulation by CREB.Decompensation of β-cells in diabetes: when pancreatic β-cells are on ICE(R).Feedback inhibition of CREB signaling promotes beta cell dysfunction in insulin resistance.Glucagon-like peptide-1 analog-mediated protection against cholesterol-induced apoptosis via mammalian target of rapamycin activation in pancreatic βTC-6 cells -1mTORβTC-6.Involvement of DPP IV/CD26 in cutaneous wound healing process in mice.Molecular Mechanism Underlying the Action of Substituted Pro-Gly Dipeptide Noopept.Phosphorylation of serine 1137/1138 of mouse insulin receptor substrate (IRS) 2 regulates cAMP-dependent binding to 14-3-3 proteins and IRS2 protein degradation.The diabetes drug liraglutide ameliorates aberrant insulin receptor localisation and signalling in parallel with decreasing both amyloid-β plaque and glial pathology in a mouse model of Alzheimer's disease.Sirolimus induces depletion of intracellular calcium stores and mitochondrial dysfunction in pancreatic beta cells.Adipose Tissue Hypoxia in Obesity and Its Impact on Preadipocytes and Macrophages: Hypoxia Hypothesis.Stabilization of hypoxia inducible factor by cobalt chloride can alter renal epithelial transport.Pleckstrin homology-like domain family A, member 3 (PHLDA3) deficiency improves islets engraftment through the suppression of hypoxic damage.
P2860
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P2860
mTOR links incretin signaling to HIF induction in pancreatic beta cells.
description
2011 nî lūn-bûn
@nan
2011 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
mTOR links incretin signaling to HIF induction in pancreatic beta cells.
@ast
mTOR links incretin signaling to HIF induction in pancreatic beta cells.
@en
type
label
mTOR links incretin signaling to HIF induction in pancreatic beta cells.
@ast
mTOR links incretin signaling to HIF induction in pancreatic beta cells.
@en
prefLabel
mTOR links incretin signaling to HIF induction in pancreatic beta cells.
@ast
mTOR links incretin signaling to HIF induction in pancreatic beta cells.
@en
P2093
P2860
P356
P1476
mTOR links incretin signaling to HIF induction in pancreatic beta cells.
@en
P2093
Marc Montminy
Meghan F Hogan
Sam Van de Velde
P2860
P304
16876-16882
P356
10.1073/PNAS.1114228108
P407
P577
2011-09-26T00:00:00Z