Genome-wide association study identifies a single major locus contributing to survival into old age; the APOE locus revisited. - Wikidata - awgldk - TriplyDB

Genome-wide association study identifies a single major locus contributing to survival into old age; the APOE locus revisited.

Genome-wide association study identifies a single major locus contributing to survival into old age; the APOE locus revisited.

http://www.wikidata.org/entity/Q35347421

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Meta‐analysis of genetic variants associated with human exceptional longevity APOE genotype and stress response - a mini review Integration of 'omics' data in aging research: from biomarkers to systems biology The three genetics (nuclear DNA, mitochondrial DNA, and gut microbiome) of longevity in humans considered as metaorganisms The search for longevity and healthy aging genes: insights from epidemiological studies and samples of long-lived individuals Genetics of healthy aging and longevity Evolutionary ecology of aging: time to reconcile field and laboratory research Decreased epigenetic age of PBMCs from Italian semi-supercentenarians and their offspring Genetic signatures of exceptional longevity in humans Genomic variants, genes, and pathways of Alzheimer's disease: An overview.Pure and Confounded Effects of Causal SNPs on Longevity: Insights for Proper Interpretation of Research Findings in GWAS of Populations with Different Genetic Structures.Biodemographic Analyses of Longitudinal Data on Aging, Health, and Longevity: Recent Advances and Future Perspectives.How Genes Modulate Patterns of Aging-Related Changes on the Way to 100: Biodemographic Models and Methods in Genetic Analyses of Longitudinal Data Adjustment for smoking does not alter the FOXO3A association with longevity.Variants near CHRNA3/5 and APOE have age- and sex-related effects on human lifespan.APOE gene polymorphism in long-lived individuals from a central China population.Effect of APOE ε4 allele on survival and fertility in an adverse environment Genome-wide association meta-analysis of human longevity identifies a novel locus conferring survival beyond 90 years of age.Gene set analysis of GWAS data for human longevity highlights the relevance of the insulin/IGF-1 signaling and telomere maintenance pathways.How to deal with the early GWAS data when imputing and combining different arrays is necessary Birth cohort differences in the prevalence of longevity-associated variants in APOE and FOXO3A in Danish long-lived individuals.Disease variants in genomes of 44 centenarians.A gain of function mutation in TNFRSF11B encoding osteoprotegerin causes osteoarthritis with chondrocalcinosis.Genetic variants in PVRL2-TOMM40-APOE region are associated with human longevity in a Han Chinese population.Genome maintenance and human longevity.The Genomic Basis of Postponed Senescence in Drosophila melanogaster.Whole-genome sequencing of the world's oldest people Genetic variants near MLST8 and DHX57 affect the epigenetic age of the cerebellum.How lifespan associated genes modulate aging changes: lessons from analysis of longitudinal data Familial longevity is marked by better cognitive performance at middle age: the Leiden Longevity Study.GWAS of longevity in CHARGE consortium confirms APOE and FOXO3 candidacy.TOMM40 rs2075650 polymorphism shows no association with neovascular age-related macular degeneration or polypoidal choroidal vasculopathy in a Chinese population.A common copy number variation (CNV) polymorphism in the CNTNAP4 gene: association with aging in females Exome sequencing of three cases of familial exceptional longevity.Atherosclerosis and Alzheimer--diseases with a common cause? Inflammation, oxysterols, vasculature Genetic analysis of TOR complex gene variation with human longevity: a nested case-control study of American men of Japanese ancestry A genome-wide association study of aging Genetics of aging, health, and survival: dynamic regulation of human longevity related traits.Age and sun exposure-related widespread genomic blocks of hypomethylation in nonmalignant skin Functional analysis of APOE locus genetic variation implicates regional enhancers in the regulation of both TOMM40 and APOE.

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Genome-wide association study identifies a single major locus contributing to survival into old age; the APOE locus revisited.

http://www.wikidata.org/entity/Q35347421

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2011 nî lūn-bûn

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2011 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2011 թվականի մայիսին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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Genome-wide association study ...... age; the APOE locus revisited.

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Genome-wide association study ...... age; the APOE locus revisited.

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J.1474-9726.2011.00705.X

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Genome-wide association study ...... age; the APOE locus revisited.

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Anton J de Craen

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Bastiaan T Heijmans

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David A Gunn

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Dennis Kremer

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Diana van Heemst

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Frans J van der Ouderaa

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H Eka D Suchiman

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Hae-Won Uh

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Lene Christiansen

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Maris Kuningas

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P2860

Bioconductor: open software development for computational biology and bioinformatics

Extending healthy life span--from yeast to humans

Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

Association of FOXO3A variation with human longevity confirmed in German centenarians

FOXO3A genotype is strongly associated with human longevity

PLINK: a tool set for whole-genome association and population-based linkage analyses

Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families

Systematic meta-analyses of Alzheimer disease genetic association studies: the AlzGene database

Lipoprotein particle profiles mark familial and sporadic human longevity

The genetics of ageing

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Fernando Rivadeneira

Cornelia M. van Duijn

Jeanine Houwing-Duistermaat

André Uitterlinden

Henning Tiemeier

Kaare Christensen

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2011-05-06T00:00:00Z

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50592168

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genome-wide association study

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3193372

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