p38γ promotes breast cancer cell motility and metastasis through regulation of RhoC GTPase, cytoskeletal architecture, and a novel leading edge behavior.
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RhoC interacts with integrin α5β1 and enhances its trafficking in migrating pancreatic carcinoma cellsA RhoC biosensor reveals differences in the activation kinetics of RhoA and RhoC in migrating cellsErbB2 and p38γ MAPK mediate alcohol-induced increase in breast cancer stem cells and metastasisChronic ethanol exposure enhances the aggressiveness of breast cancer: the role of p38γCellular and molecular mechanisms underlying alcohol-induced aggressiveness of breast cancerSingle-cell Migration Chip for Chemotaxis-based Microfluidic Selection of Heterogeneous Cell PopulationsLoss-of-function RNAi screens in breast cancer cells identify AURKB, PLK1, PIK3R1, MAPK12, PRKD2, and PTK6 as sensitizing targets of rapamycin activityTumor cell migration screen identifies SRPK1 as breast cancer metastasis determinant.RhoC and ROCKs regulate cancer cell interactions with endothelial cells.p38γ mitogen-activated protein kinase (MAPK) confers breast cancer hormone sensitivity by switching estrogen receptor (ER) signaling from classical to nonclassical pathway via stimulating ER phosphorylation and c-Jun transcription.The dynamics of Rho GTPase signaling and implications for targeting cancer and the tumor microenvironment.Killing of Kras-mutant colon cancer cells via Rac-independent actin remodeling by the βGBP cytokine, a physiological PI3K inhibitor therapeutically effective in vivoExposure to ionizing radiation induced persistent gene expression changes in mouse mammary glandp38γ MAPK Is a Therapeutic Target for Triple-Negative Breast Cancer by Stimulation of Cancer Stem-Like Cell Expansion.Progesterone receptor isoforms PRA and PRB differentially contribute to breast cancer cell migration through interaction with focal adhesion kinase complexesEZH2 inhibition decreases p38 signaling and suppresses breast cancer motility and metastasisDown-regulation of miR-125a-5p is associated with salivary adenoid cystic carcinoma progression via targeting p38/JNK/ERK signal pathway.Clinicopathological significance of p38β, p38γ, and p38δ and its biological roles in esophageal squamous cell carcinoma.Detecting pairwise interactive effects of continuous random variables for bimarker identification with small sample size.Rho-kinase regulation of TNF-α-induced nuclear translocation of NF-κB RelA/p65 and M-CSF expression via p38 MAPK in mesangial cells.Identification of a ternary protein-complex as a therapeutic target for K-Ras-dependent colon cancer.Lysosome trafficking is necessary for EGF-driven invasion and is regulated by p38 MAPK and Na+/H+ exchangers.Is p38γ MAPK a metastasis-promoting gene or an oncogenic property-maintaining gene?Rethinking the war on cancer: multidisciplinary collaborations between biologists and physical scientists.Alcohol and Cancer Stem Cells.The K-Ras effector p38γ MAPK confers intrinsic resistance to tyrosine kinase inhibitors by stimulating EGFR transcription and EGFR dephosphorylation.p38γ MAPK is required for inflammation-associated colon tumorigenesis.MAPKs' status at early stages of renal carcinogenesis and tumors induced by ferric nitrilotriacetate.
P2860
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P2860
p38γ promotes breast cancer cell motility and metastasis through regulation of RhoC GTPase, cytoskeletal architecture, and a novel leading edge behavior.
description
2011 nî lūn-bûn
@nan
2011 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
p38γ promotes breast cancer ce ...... a novel leading edge behavior.
@ast
p38γ promotes breast cancer ce ...... a novel leading edge behavior.
@en
type
label
p38γ promotes breast cancer ce ...... a novel leading edge behavior.
@ast
p38γ promotes breast cancer ce ...... a novel leading edge behavior.
@en
prefLabel
p38γ promotes breast cancer ce ...... a novel leading edge behavior.
@ast
p38γ promotes breast cancer ce ...... a novel leading edge behavior.
@en
P2093
P2860
P1433
P1476
p38γ promotes breast cancer ce ...... a novel leading edge behavior.
@en
P2093
Alejandra C Ventura
Celina G Kleer
Devin T Rosenthal
Ellen M Arruda
Harish Iyer
Krishna Garikipati
Silvia Escudero
Sofia D Merajver
P2860
P304
P356
10.1158/0008-5472.CAN-11-1291
P407
P577
2011-08-23T00:00:00Z