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Organic carbamates in drug design and medicinal chemistry

Organic carbamates in drug design and medicinal chemistry

http://www.wikidata.org/entity/Q35365543

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(11)C[double bond, length as m-dash]O bonds made easily for positron emission tomography radiopharmaceuticals Chemoselective Synthesis of Carbamates using CO2 as Carbon Source.In vivo instability of platensimycin and platencin: Synthesis and biological evaluation of urea- and carbamate-platensimycin.Synthesis of 2-Aryl- and 2-Vinylpyrrolidines via Copper-Catalyzed Coupling of Styrenes and Dienes with Potassium β-Aminoethyl Trifluoroborates Novel Natural Product-like Caged Xanthones Bearing a Carbamate Moiety Exhibit Antitumor Potency and Anti-Angiogenesis Activity In vivo.Anticancer activity profiling of parthenolide analogs generated via P450-mediated chemoenzymatic synthesis.Chalcone-based carbamates for Alzheimer's disease treatment.Synthesis and Antimicrobial Evaluation of 1-[(2-Substituted phenyl)carbamoyl]naphthalen-2-yl Carbamates.Design, Synthesis, and Antimicrobial Evaluation of a Novel Bone-Targeting Bisphosphonate-Ciprofloxacin Conjugate for the Treatment of Osteomyelitis Biofilms.Sustaining Intravitreal Residence With L-Arginine Peptide-Conjugated Nanocarriers.Amino Acid Carbamates As Prodrugs Of Resveratrol.Inhibiting mitochondrial phosphate transport as an unexploited antifungal strategy.Design of a Photoredox Catalyst that Enables the Direct Synthesis of Carbamate-Protected Primary Amines via Photoinduced, Copper-Catalyzed N-Alkylation Reactions of Unactivated Secondary Halides.Proline-Based Carbamates as Cholinesterase Inhibitors.Halogenated 1-Hydroxynaphthalene-2-Carboxanilides Affecting Photosynthetic Electron Transport in Photosystem II.Synthesis and In Vitro Antimycobacterial Activity of Novel N-Arylpiperazines Containing an Ethane-1,2-diyl Connecting Chain.Efficient preparation of carbamates by Rh-catalysed oxidative carbonylation: unveiling the role of the oxidant.Iron-Catalyzed Reaction of Urea with Alcohols and Amines: A Safe Alternative for the Synthesis of Primary Carbamates.A One-Pot Synthesis of N-Aryl-2-Oxazolidinones and Cyclic Urethanes by the Lewis Base Catalyzed Fixation of Carbon Dioxide into Anilines and Bromoalkanes.An electrospray ionization mass spectrometry study of azidoacetic acid/transition metal complexes.Teaching Old Compounds New Tricks: DDQ-Photocatalyzed C-H Amination of Arenes with Carbamates, Urea, and N-Heterocycles.A Simple Zinc Catalyst for Carbamate Synthesis Directly from CO2.nBu4NI-catalyzed oxidative cross-coupling of carbon dioxide, amines, and aryl ketones: access to O-β-oxoalkyl carbamates.A Novel Way To Radiolabel Human Butyrylcholinesterase for Positron Emission Tomography through Irreversible Transfer of the Radiolabeled Moiety.Highly potent visnagin derivatives inhibit Cyp1 and prevent doxorubicin cardiotoxicity.Photosynthesis-Inhibiting Activity of 1-[(2-Chlorophenyl)carbamoyl]- and 1-[(2-Nitrophenyl)carbamoyl]naphthalen-2-yl Alkylcarbamates.Base-promoted coupling of carbon dioxide, amines, and diaryliodonium salts: a phosgene- and metal-free route to O-aryl carbamates.Exploration of Novel Chemical Space: Synthesis and in vitro Evaluation of N-Functionalized Tertiary Sulfonimidamides.Water-soluble derivatives of 4-oxo-N-(4-hydroxyphenyl) retinamide: synthesis and biological activity.Ionic liquids as an electrolyte for the electro synthesis of organic compounds.Stereoselective Synthesis of Isoxazolidines via Copper-Catalyzed Alkene Diamination.Development of a Janus Kinase Inhibitor Prodrug for the Treatment of Rheumatoid Arthritis Oximes as reusable templates for the synthesis of ureas and carbamates by an in situ generation of carbamoyl oximes Direct synthesis of carbamate from CO2 using a task-specific ionic liquid catalyst Harnessing the pyrroloquinoxaline scaffold for FAAH and MAGL interaction: definition of the structural determinants for enzyme inhibition

P2860

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P2860

Organic carbamates in drug design and medicinal chemistry

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2015 nî lūn-bûn

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2015 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2015 թվականի ապրիլին հրատարակված գիտական հոդված

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2015年の論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年论文

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Organic carbamates in drug design and medicinal chemistry

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Organic carbamates in drug design and medicinal chemistry

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Organic carbamates in drug design and medicinal chemistry

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Organic carbamates in drug design and medicinal chemistry

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Organic carbamates in drug design and medicinal chemistry

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P2093

Arun K Ghosh

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Margherita Brindisi

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Crystal structure of the human monoacylglycerol lipase, a key actor in endocannabinoid signaling

Selective blockade of 2-arachidonoylglycerol hydrolysis produces cannabinoid behavioral effects

Active human immunodeficiency virus protease is required for viral infectivity

A phase I trial of antibody directed enzyme prodrug therapy (ADEPT) in patients with advanced colorectal carcinoma or other CEA producing tumours

A comprehensive profile of brain enzymes that hydrolyze the endocannabinoid 2-arachidonoylglycerol

Mechanism of carbamate inactivation of FAAH: implications for the design of covalent inhibitors and in vivo functional probes for enzymes

Darunavir, a conceptually new HIV-1 protease inhibitor for the treatment of drug-resistant HIV

Therapeutic potential of monoacylglycerol lipase inhibitors

SCH 503034, a mechanism-based inhibitor of hepatitis C virus NS3 protease, suppresses polyprotein maturation and enhances the antiviral activity of alpha interferon in replicon cells.

Structure of the protease domain of memapsin 2 (beta-secretase) complexed with inhibitor

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2895-2940

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carboxylic acid

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