Normal glucagon signaling and β-cell function after near-total α-cell ablation in adult mice - Wikidata - awgldk - TriplyDB

Normal glucagon signaling and β-cell function after near-total α-cell ablation in adult mice

Normal glucagon signaling and β-cell function after near-total α-cell ablation in adult mice

http://www.wikidata.org/entity/Q35404726

about

The inactivation of Arx in pancreatic α-cells triggers their neogenesis and conversion into functional β-like cells Stereological analyses of the whole human pancreas.Current status of regeneration of pancreatic β-cells Artemisinins Target GABAA Receptor Signaling and Impair α Cell Identity Quantification of the glycemic response to microdoses of subcutaneous glucagon at varying insulin levels.Glucagonocentric restructuring of diabetes: a pathophysiologic and therapeutic makeover Diabetes recovery by age-dependent conversion of pancreatic δ-cells into insulin producers.Angptl4 links α-cell proliferation following glucagon receptor inhibition with adipose tissue triglyceride metabolism.The FOXP1, FOXP2 and FOXP4 transcription factors are required for islet alpha cell proliferation and function in mice.Leptin signaling regulates glucose homeostasis, but not adipostasis, in the zebrafish.Euglycemia Restoration by Central Leptin in Type 1 Diabetes Requires STAT3 Signaling but Not Fast-Acting Neurotransmitter Release.UCP2 regulates the glucagon response to fasting and starvation Endogenous GIP ameliorates impairment of insulin secretion in proglucagon-deficient mice under moderate beta cell damage induced by streptozotocin Beta Cell Regeneration in Adult Mice: Controversy Over the Involvement of Stem Cells.Role of KATP channels in glucose-regulated glucagon secretion and impaired counterregulation in type 2 diabetes.Modeling the pancreatic α-cell: dual mechanisms of glucose suppression of glucagon secretion.Restoring insulin production for type 1 diabetes.K(ATP) channels and islet hormone secretion: new insights and controversies.In vivo reprogramming for tissue repair.Islet α cells and glucagon--critical regulators of energy homeostasis.Hypoglycemic Effect of Combined Ghrelin and Glucagon Receptor Blockade.A synopsis of factors regulating beta cell development and beta cell mass.Regeneration of pancreatic insulin-producing cells by in situ adaptive cell conversion.Advances in β cell replacement and regeneration strategies for treating diabetes Predominant role of active versus facilitative glucose transport for glucagon-like peptide-1 secretion.Increased biogenesis of glucagon-containing secretory granules and glucagon secretion in BIG3-knockout mice.Morphological assessment of pancreatic islet hormone content following aerobic exercise training in rats with poorly controlled Type 1 diabetes mellitus.LKB1 and AMPKα1 are required in pancreatic alpha cells for the normal regulation of glucagon secretion and responses to hypoglycemia Conversion of mature human β-cells into glucagon-producing α-cells.Development and regeneration in the endocrine pancreas Endogenous Reprogramming of Alpha Cells into Beta Cells, Induced by Viral Gene Therapy, Reverses Autoimmune Diabetes.Loss of mTORC1 signaling alters pancreatic α cell mass and impairs glucagon secretion.α-Cells are dispensable in postnatal morphogenesis and maturation of mouse pancreatic islets.Glucose metabolism is altered after loss of L cells and α-cells but not influenced by loss of K cells.Technical Resource article (METHODS AND TOOLS).Dnmt1 activity is dispensable in δ-cells but is essential for α-cell homeostasis.The sixth annual translational stem cell research conference of the New York Stem Cell Foundation.The Cells of the Islets of Langerhans.Acute disruption of glucagon secretion or action does not improve glucose tolerance in an insulin-deficient mouse model of diabetes.Chronic fractalkine administration improves glucose tolerance and pancreatic endocrine function.

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Normal glucagon signaling and β-cell function after near-total α-cell ablation in adult mice

http://www.wikidata.org/entity/Q35404726

description

2011 nî lūn-bûn

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2011 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

Normal glucagon signaling and ...... α-cell ablation in adult mice

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Normal glucagon signaling and ...... α-cell ablation in adult mice

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Normal glucagon signaling and ...... α-cell ablation in adult mice

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Normal glucagon signaling and ...... α-cell ablation in adult mice

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Normal glucagon signaling and ...... α-cell ablation in adult mice

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Normal glucagon signaling and ...... α-cell ablation in adult mice

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Normal glucagon signaling and ...... α-cell ablation in adult mice

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Andreas Wiederkehr

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Bernard Thorens

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Claes B Wollheim

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Fabrizio Thorel

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Nicolas Damond

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Paolo Meda

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Pedro L Herrera

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Simona Chera

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P2860

The ectopic expression of Pax4 in the mouse pancreas converts progenitor cells into alpha and subsequently beta cells

Homozygous P86S mutation of the human glucagon receptor is associated with hyperglucagonemia, alpha cell hyperplasia, and islet cell tumor

Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus

Glucagon receptors on human islet cells contribute to glucose competence of insulin release

Unique mechanisms of growth regulation and tumor suppression upon Apc inactivation in the pancreas

Lower blood glucose, hyperglucagonemia, and pancreatic alpha cell hyperplasia in glucagon receptor knockout mice

Adult pancreatic beta-cells are formed by self-duplication rather than stem-cell differentiation

Mice deficient for glucagon gene-derived peptides display normoglycemia and hyperplasia of islet {alpha}-cells but not of intestinal L-cells

Unique arrangement of alpha- and beta-cells in human islets of Langerhans

Conversion of adult pancreatic alpha-cells to beta-cells after extreme beta-cell loss

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