Myocardin-related transcription factors A and B are key regulators of TGF-β1-induced fibroblast to myofibroblast differentiation. - Wikidata - awgldk - TriplyDB

Myocardin-related transcription factors A and B are key regulators of TGF-β1-induced fibroblast to myofibroblast differentiation.

Myocardin-related transcription factors A and B are key regulators of TGF-β1-induced fibroblast to myofibroblast differentiation.

http://www.wikidata.org/entity/Q35417672

about

Evolving Insights on Metabolism, Autophagy, and Epigenetics in Liver Myofibroblasts The myofibroblast in wound healing and fibrosis: answered and unanswered questions Recent developments in myofibroblast biology: paradigms for connective tissue remodeling From tissue mechanics to transcription factors.Context-dependent switch in chemo/mechanotransduction via multilevel crosstalk among cytoskeleton-regulated MRTF and TAZ and TGFβ-regulated Smad3 Whole animal knockout of smooth muscle alpha-actin does not alter excisional wound healing or the fibroblast-to-myofibroblast transition Targeting the myofibroblast genetic switch: inhibitors of myocardin-related transcription factor/serum response factor-regulated gene transcription prevent fibrosis in a murine model of skin injury.Cell geometry dictates TNFα-induced genome response.Prostaglandin E2 inhibits α-smooth muscle actin transcription during myofibroblast differentiation via distinct mechanisms of modulation of serum response factor and myocardin-related transcription factor-A Hypoxia preconditioned mesenchymal stem cells prevent cardiac fibroblast activation and collagen production via leptin.Megakaryoblastic leukemia-1 is required for the development of bleomycin-induced pulmonary fibrosis A Role of Myocardin Related Transcription Factor-A (MRTF-A) in Scleroderma Related Fibrosis Modulation of human valve interstitial cell phenotype and function using a fibroblast growth factor 2 formulation Myocardin-Related Transcription Factor A Epigenetically Regulates Renal Fibrosis in Diabetic Nephropathy.Improved throughput traction microscopy reveals pivotal role for matrix stiffness in fibroblast contractility and TGF-β responsiveness.Matrix stiffness-induced myofibroblast differentiation is mediated by intrinsic mechanotransduction.A TRPC6-dependent pathway for myofibroblast transdifferentiation and wound healing in vivo.MBNL1-mediated regulation of differentiation RNAs promotes myofibroblast transformation and the fibrotic response.Hic-5 is required for myofibroblast differentiation by regulating mechanically dependent MRTF-A nuclear accumulation Transcriptional control of cardiac fibroblast plasticity.Inhibition of mechanosensitive signaling in myofibroblasts ameliorates experimental pulmonary fibrosis Activation of MRTF-A-dependent gene expression with a small molecule promotes myofibroblast differentiation and wound healing Lysophosphatidic acid accelerates lung fibrosis by inducing differentiation of mesenchymal stem cells into myofibroblasts.Genesis of the myofibroblast in lung injury and fibrosis.The actin-MRTF-SRF gene regulatory axis and myofibroblast differentiation.Matrix mechanics and regulation of the fibroblast phenotype.Extracellular matrix synthesis in vascular disease: hypertension, and atherosclerosis.Substrate stiffness-dependent regulation of the SRF-Mkl1 co-activator complex requires the inner nuclear membrane protein Emerin.Stromal dynamic reciprocity in cancer: intricacies of fibroblastic-ECM interactions.Transforming Growth Factor β1 Function in Airway Remodeling and Hyperresponsiveness. The Missing Link?MMP-2 expression by fibroblasts is suppressed by the myofibroblast phenotype.MRTFs- master regulators of EMT.How do your contacts (or their absence) shape your fate?In search of novel targets for heart disease: myocardin and myocardin-related transcriptional cofactors.Mechanoregulation of the Myofibroblast in Wound Contraction, Scarring, and Fibrosis: Opportunities for New Therapeutic Intervention.NADPH oxidase 4 induces cardiac fibrosis and hypertrophy through activating Akt/mTOR and NFκB signaling pathways.Current concepts related to hypertrophic scarring in burn injuries.Transforming growth factor-β (TGF-β) activation in cutaneous wounds after topical application of aloe vera gel.Vascular disease-causing mutation, smooth muscle α-actin R258C, dominantly suppresses functions of α-actin in human patient fibroblasts.MicroRNA-21 preserves the fibrotic mechanical memory of mesenchymal stem cells.

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P2860

Myocardin-related transcription factors A and B are key regulators of TGF-β1-induced fibroblast to myofibroblast differentiation.

http://www.wikidata.org/entity/Q35417672

description

2011 nî lūn-bûn

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2011 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2011 թվականի հուլիսին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

Myocardin-related transcriptio ...... myofibroblast differentiation.

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Myocardin-related transcriptio ...... myofibroblast differentiation.

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type

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Myocardin-related transcriptio ...... myofibroblast differentiation.

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Myocardin-related transcriptio ...... myofibroblast differentiation.

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Myocardin-related transcriptio ...... myofibroblast differentiation.

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Myocardin-related transcriptio ...... myofibroblast differentiation.

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Journal of Investigative Dermatology

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Myocardin-related transcriptio ...... myofibroblast differentiation.

@en

P2093

Beverly J Crider

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Carol J Haaksma

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Eric W Howard

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George M Risinger

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James J Tomasek

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P2860

Expression profiling of serum inducible genes identifies a subset of SRF target genes that are MKL dependent

Signal-regulated activation of serum response factor is mediated by changes in actin dynamics

Potentiation of serum response factor activity by a family of myocardin-related transcription factors.

Megakaryoblastic leukemia 1, a potent transcriptional coactivator for serum response factor (SRF), is required for serum induction of SRF target genes

Dual roles of myocardin-related transcription factors in epithelial mesenchymal transition via slug induction and actin remodeling

Myofibroblasts and mechano-regulation of connective tissue remodelling

Induction of vascular smooth muscle alpha-actin gene transcription in transforming growth factor beta1-activated myofibroblasts mediated by dynamic interplay between the Pur repressor proteins and Sp1/Smad coactivators

Force activates smooth muscle alpha-actin promoter activity through the Rho signaling pathway

Actin dynamics control SRF activity by regulation of its coactivator MAL

Measuring mechanical tension across vinculin reveals regulation of focal adhesion dynamics.

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2378-2385

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10.1038/JID.2011.219

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12

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51508557

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21776010

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3199034

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