Levodopa deactivates enzymes that regulate thiol-disulfide homeostasis and promotes neuronal cell death: implications for therapy of Parkinson's disease.
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The role of oxidative stress in Parkinson's diseaseEmerging preclinical pharmacological targets for Parkinson's diseaseDysregulation of glutathione homeostasis in neurodegenerative diseasesMechanisms of altered redox regulation in neurodegenerative diseases--focus on S--glutathionylationProtein-thiol oxidation and cell death: regulatory role of glutaredoxinsS-glutathionylation: from molecular mechanisms to health outcomesMaternally inherited genetic variants of CADPS2 are present in autism spectrum disorders and intellectual disability patients.Regulation of DJ-1 by Glutaredoxin 1 in Vivo: Implications for Parkinson's Disease.Evaluation of a dithiocarbamate derivative as an inhibitor of human glutaredoxin-1.Glutaredoxin deficiency exacerbates neurodegeneration in C. elegans models of Parkinson's disease.Thiol redox homeostasis in neurodegenerative diseaseThe roles of redox enzymes in Parkinson's disease: Focus on glutaredoxin.Thiol-redox signaling, dopaminergic cell death, and Parkinson's diseaseGlutaredoxin 1 protects dopaminergic cells by increased protein glutathionylation in experimental Parkinson's disease.Upregulation of Glutaredoxin-1 Activates Microglia and Promotes Neurodegeneration: Implications for Parkinson's DiseaseAntioxidant and bioenergetic coupling between neurons and astrocytes.Detoxification and antioxidative therapy for levodopa-induced neurodegeneration in Parkinson's disease.Current and investigational non-dopaminergic agents for management of motor symptoms (including motor complications) in Parkinson's disease.Levodopa activates apoptosis signaling kinase 1 (ASK1) and promotes apoptosis in a neuronal model: implications for the treatment of Parkinson's disease.Nondopaminergic therapy of motor and nonmotor symptoms in Parkinson's disease: a clinician's perspective.Neuroprotective potentials of neurotrophin rich olfactory ensheathing cell's conditioned media against 6OHDA-induced oxidative damage.Use of monoamine oxidase inhibitors in chronic neurodegeneration.Aberrant CpG Methylation Mediates Abnormal Transcription of MAO-A Induced by Acute and Chronic L-3,4-Dihydroxyphenylalanine Administration in SH-SY5Y Neuronal Cells.Novel chloroacetamido compound CWR-J02 is an anti-inflammatory glutaredoxin-1 inhibitor.Levodopa, placebo and rotigotine change biomarker levels for oxidative stress.Levodopa increases oxidative stress and repulsive guidance molecule A levels: a pilot study in patients with Parkinson's disease.
P2860
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P2860
Levodopa deactivates enzymes that regulate thiol-disulfide homeostasis and promotes neuronal cell death: implications for therapy of Parkinson's disease.
description
2010 nî lūn-bûn
@nan
2010 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մարտին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Levodopa deactivates enzymes t ...... herapy of Parkinson's disease.
@ast
Levodopa deactivates enzymes t ...... herapy of Parkinson's disease.
@en
type
label
Levodopa deactivates enzymes t ...... herapy of Parkinson's disease.
@ast
Levodopa deactivates enzymes t ...... herapy of Parkinson's disease.
@en
prefLabel
Levodopa deactivates enzymes t ...... herapy of Parkinson's disease.
@ast
Levodopa deactivates enzymes t ...... herapy of Parkinson's disease.
@en
P2093
P2860
P356
P1433
P1476
Levodopa deactivates enzymes t ...... herapy of Parkinson's disease.
@en
P2093
Anne M Distler
Elizabeth A Sabens
John J Mieyal
P2860
P304
P356
10.1021/BI9018658
P407
P577
2010-03-01T00:00:00Z