Melanocortin 4 receptor-deficient mice as a novel mouse model of nonalcoholic steatohepatitis.
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Utilization of animal models to investigate non-alcoholic steatohepatitis-associated hepatocellular carcinomaHow Useful Are Monogenic Rodent Models for the Study of Human Non-Alcoholic Fatty Liver Disease?Severe Atherosclerosis and Hypercholesterolemia in Mice Lacking Both the Melanocortin Type 4 Receptor and Low Density Lipoprotein ReceptorIn vitro and in vivo models of non-alcoholic fatty liver disease (NAFLD).Inhibition of the central melanocortin system decreases brown adipose tissue activityCholesterol-lowering drugs cause dissolution of cholesterol crystals and disperse Kupffer cell crown-like structures during resolution of NASH.Translocator protein 18 kDa (TSPO) is regulated in white and brown adipose tissue by obesityHepatic crown-like structure: a unique histological feature in non-alcoholic steatohepatitis in mice and humansEicosapentaenoic acid ameliorates non-alcoholic steatohepatitis in a novel mouse model using melanocortin 4 receptor-deficient miceEfficacy of Dietary Lipid Control in Healing High-Fat and High-Cholesterol Diet-Induced Fibrotic Steatohepatitis in Rats.Probiotic treatment reduces appetite and glucose level in the zebrafish model.Development of a novel mouse model of hepatocellular carcinoma with nonalcoholic steatohepatitis using a high-fat, choline-deficient diet and intraperitoneal injection of diethylnitrosamineStrategies, models and biomarkers in experimental non-alcoholic fatty liver disease researchAltered hepatic lipid metabolism in mice lacking both the melanocortin type 4 receptor and low density lipoprotein receptorHedgehog signaling is a potent regulator of liver lipid metabolism and reveals a GLI-code associated with steatosis.The expanding role of fish models in understanding non-alcoholic fatty liver disease.Rodent models of nonalcoholic fatty liver disease/nonalcoholic steatohepatitis.Antifibrotic effect of pirfenidone in a mouse model of human nonalcoholic steatohepatitis.Recent advances in mouse models of obesity- and nonalcoholic steatohepatitis-associated hepatocarcinogenesis.Aggressive Crosstalk Between Fatty Acids and Inflammation in Macrophages and Their Influence on Metabolic Homeostasis.New insight into inter-organ crosstalk contributing to the pathogenesis of non-alcoholic fatty liver disease (NAFLD).Omega-3 polyunsaturated fatty acids as a treatment strategy for nonalcoholic fatty liver disease.A novel diet-induced murine model of steatohepatitis with fibrosis for screening and evaluation of drug candidates for nonalcoholic steatohepatitis.Seven weeks of Western diet in apolipoprotein-E-deficient mice induce metabolic syndrome and non-alcoholic steatohepatitis with liver fibrosisDevelopmental Programming of Obesity and Liver Metabolism by Maternal Perinatal Nutrition Involves the Melanocortin System.Hepatocellular carcinoma in a mouse model fed a choline-deficient, L-amino acid-defined, high-fat diet.Animal Models of Nonalcoholic Fatty Liver Disease-A Starter's Guide.Synthetic "smart gel" provides glucose-responsive insulin delivery in diabetic mice.Gut microbiota-mediated generation of saturated fatty acids elicits inflammation in the liver in murine high-fat diet-induced steatohepatitis.Calpain Inhibition Attenuates Adipose Tissue Inflammation and Fibrosis in Diet-induced Obese Mice.CD11c+ resident macrophages drive hepatocyte death-triggered liver fibrosis in a murine model of nonalcoholic steatohepatitis.Canagliflozin, an SGLT2 inhibitor, attenuates the development of hepatocellular carcinoma in a mouse model of human NASH.Macrophage-inducible C-type lectin underlies obesity-induced adipose tissue fibrosis.Eicosapentaenoic acid attenuates obesity-related hepatocellular carcinogenesis.Report of the Japan Diabetes Society/Japanese Cancer Association Joint Committee on Diabetes and Cancer.Subdiaphragmatic Vagotomy With Pyloroplasty Ameliorates the Obesity Caused by Genetic Deletion of the Melanocortin 4 Receptor in the Mouse.Bile acid metabolism regulated by the gut microbiota promotes non-alcoholic steatohepatitis-associated hepatocellular carcinoma in mice.Non-alcoholic steatohepatitis-associated hepatic fibrosis and hepatocellular carcinoma in a combined mouse model of genetic modification and dietary challenge.Spontaneous onset of nonalcoholic steatohepatitis and hepatocellular carcinoma in a mouse model of metabolic syndrome.Mouse models for investigating the underlying mechanisms of nonalcoholic steatohepatitis-derived hepatocellular carcinoma.
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P2860
Melanocortin 4 receptor-deficient mice as a novel mouse model of nonalcoholic steatohepatitis.
description
2011 nî lūn-bûn
@nan
2011 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Melanocortin 4 receptor-defici ...... nonalcoholic steatohepatitis.
@ast
Melanocortin 4 receptor-defici ...... nonalcoholic steatohepatitis.
@en
type
label
Melanocortin 4 receptor-defici ...... nonalcoholic steatohepatitis.
@ast
Melanocortin 4 receptor-defici ...... nonalcoholic steatohepatitis.
@en
prefLabel
Melanocortin 4 receptor-defici ...... nonalcoholic steatohepatitis.
@ast
Melanocortin 4 receptor-defici ...... nonalcoholic steatohepatitis.
@en
P2093
P2860
P1476
Melanocortin 4 receptor-defici ...... f nonalcoholic steatohepatitis
@en
P2093
Isao Sakaida
Michiko Itoh
Miyako Tanaka
Nobutaka Nakagawa
Shuji Terai
Takayoshi Suganami
Yasutomi Kamei
Yoshihiro Ogawa
P2860
P304
P356
10.1016/J.AJPATH.2011.07.014
P407
P577
2011-09-07T00:00:00Z