CD8+ T cell dysfunction and increase in murine gammaherpesvirus latent viral burden in the absence of 4-1BB ligand
about
Enhanced response of T cells from murine gammaherpesvirus 68-infected mice lacking the suppressor of T cell receptor signaling molecules Sts-1 and Sts-2CD27 stimulation promotes the frequency of IL-7 receptor-expressing memory precursors and prevents IL-12-mediated loss of CD8(+) T cell memory in the absence of CD4(+) T cell help.Perturbation of lytic and latent gammaherpesvirus infection in the absence of the inhibitory receptor CEACAM1Opposing positive and negative regulation of T cell activity during viral persistence.Control of memory CD8+ T cell differentiation by CD80/CD86-CD28 costimulation and restoration by IL-2 during the recall response.Biphasic role of 4-1BB in the regulation of mouse cytomegalovirus-specific CD8(+) T cellsDispensable role for 4-1BB and 4-1BBL in development of vaccinia virus-specific CD8 T cellsCD137 differentially regulates innate and adaptive immunity against Mycobacterium tuberculosis.CD8(+) T cells from mice transnuclear for a TCR that recognizes a single H-2K(b)-restricted MHV68 epitope derived from gB-ORF8 help control infection.Targeting 4-1BB (CD137) to enhance CD8 T cell responses with poxviruses and viral antigens.Primary clearance of murine gammaherpesvirus 68 by PKCtheta-/- CD8 T cells is compromised in the absence of help from CD4 T cells.Cutting edge: IL-2 immune complexes as a therapy for persistent virus infection.The diversity of costimulatory and inhibitory receptor pathways and the regulation of antiviral T cell responses.Costimulation signals for memory CD8+ T cells during viral infections.Tumor necrosis factor receptor/tumor necrosis factor family members in antiviral CD8 T-cell immunity.T-cell intrinsic effects of GITR and 4-1BB during viral infection and cancer immunotherapy.T-cell costimulatory blockade in organ transplantation.Simultaneous analysis of in vivo CD8+ T cell cytotoxicity against multiple epitopes using multicolor flow cytometry.CD137 ligand signaling enhances myelopoiesis during infections.CD137 Plays Both Pathogenic and Protective Roles in Type 1 Diabetes Development in NOD Mice.
P2860
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P2860
CD8+ T cell dysfunction and increase in murine gammaherpesvirus latent viral burden in the absence of 4-1BB ligand
description
2007 nî lūn-bûn
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2007 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2007年の論文
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2007年学术文章
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2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
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2007年學術文章
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name
CD8+ T cell dysfunction and in ...... in the absence of 4-1BB ligand
@ast
CD8+ T cell dysfunction and in ...... in the absence of 4-1BB ligand
@en
type
label
CD8+ T cell dysfunction and in ...... in the absence of 4-1BB ligand
@ast
CD8+ T cell dysfunction and in ...... in the absence of 4-1BB ligand
@en
prefLabel
CD8+ T cell dysfunction and in ...... in the absence of 4-1BB ligand
@ast
CD8+ T cell dysfunction and in ...... in the absence of 4-1BB ligand
@en
P2093
P2860
P1476
CD8+ T cell dysfunction and in ...... in the absence of 4-1BB ligand
@en
P2093
Edward J Usherwood
Hideo Yagita
Sarah Bellfy
Shinichiro Fuse
P2860
P304
P356
10.4049/JIMMUNOL.178.8.5227
P407
P577
2007-04-01T00:00:00Z