Glutathione S-transferase A1 genetic variants reduce busulfan clearance in children undergoing hematopoietic cell transplantation. - Wikidata - awgldk - TriplyDB

Glutathione S-transferase A1 genetic variants reduce busulfan clearance in children undergoing hematopoietic cell transplantation.

Glutathione S-transferase A1 genetic variants reduce busulfan clearance in children undergoing hematopoietic cell transplantation.

http://www.wikidata.org/entity/Q35486314

about

Identification and utilization of donor and recipient genetic variants to predict survival after HCT: are we ready for primetime?Glutathione transferase-A2 S112T polymorphism predicts survival, transplant-related mortality, busulfan and bilirubin blood levels after allogeneic stem cell transplantation.Pharmacometabolomics for predicting variable busulfan exposure in paediatric haematopoietic stem cell transplantation patients.Busulfan in hematopoietic stem cell transplantation Pharmacogenetics of intravenous and oral busulfan in hematopoietic cell transplant recipients.Population pharmacokinetics of busulfan in pediatric and young adult patients undergoing hematopoietic cell transplant: a model-based dosing algorithm for personalized therapy and implementation into routine clinical use.Glutathione Transferase Gene Variants Influence Busulfan Pharmacokinetics and Outcome After Myeloablative Conditioning.Influence of glutathione S-transferase gene polymorphisms on busulfan pharmacokinetics and outcome of hematopoietic stem-cell transplantation in thalassemia pediatric patients Optimizing drug development of anti-cancer drugs in children using modelling and simulation.Variation in prescribing patterns and therapeutic drug monitoring of intravenous busulfan in pediatric hematopoietic cell transplant recipients Effect of casopitant, a novel NK-1 antagonist, on the pharmacokinetics of dolasetron and granisetron.Effect of weight and maturation on busulfan clearance in infants and small children undergoing hematopoietic cell transplantation.Busulfan in hematopoietic stem cell transplant setting.Part 3: Pharmacogenetic variability in phase II anticancer drug metabolism.An analysis of the therapeutic benefits of genotyping in pediatric hematopoietic stem cell transplantation.Glutathione S-transferase gene variations influence BU pharmacokinetics and outcome of hematopoietic SCT in pediatric patients.Can the pharmacogenetics of GST gene polymorphisms predict the dose of busulfan in pediatric hematopoietic stem cell transplantation?Unexpectedly high AUC levels in a child who received intravenous busulfan before stem cell transplantation.Influence of GST gene polymorphisms on busulfan pharmacokinetics in children.GSTA1 diplotypes affect busulfan clearance and toxicity in children undergoing allogeneic hematopoietic stem cell transplantation: a multicenter study.Population pharmacokinetics and pharmacodynamics of busulfan with GSTA1 polymorphisms in patients undergoing allogeneic hematopoietic stem cell transplantation.Population pharmacokinetics analysis of intravenous busulfan in Chinese patients undergoing hematopoietic stem cell transplantation.New insights into the pharmacokinetics of intravenous busulfan in children with sickle cell anemia undergoing bone marrow transplantation.Clarifying busulfan metabolism and drug interactions to support new therapeutic drug monitoring strategies: a comprehensive review.Pharmacokinetics-adapted Busulfan-based myeloablative conditioning before unrelated umbilical cord blood transplantation for myeloid malignancies in children.Development of multiplex PCR method for the analysis of glutathione s-transferase polymorphism.Effect of genetic variants GSTA1 and CYP39A1 and age on busulfan clearance in pediatric patients undergoing hematopoietic stem cell transplantation.

P2860

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P2860

Glutathione S-transferase A1 genetic variants reduce busulfan clearance in children undergoing hematopoietic cell transplantation.

http://www.wikidata.org/entity/Q35486314

description

2008 nî lūn-bûn

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2008 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2008 թվականի հուլիսին հրատարակված գիտական հոդված

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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name

Glutathione S-transferase A1 g ...... opoietic cell transplantation.

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Glutathione S-transferase A1 g ...... opoietic cell transplantation.

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type

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Glutathione S-transferase A1 g ...... opoietic cell transplantation.

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Glutathione S-transferase A1 g ...... opoietic cell transplantation.

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Glutathione S-transferase A1 g ...... opoietic cell transplantation.

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0091270008321940

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The Journal of Clinical Pharmacology

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Glutathione S-transferase A1 g ...... opoietic cell transplantation.

@en

P2093

Erica Langer

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Julie A Ross

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K Scott Baker

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L'Aurelle Johnson

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Pamala A Jacobson

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Paul J Orchard

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Qing Cao

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Richard Brundage

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Rory Remmel

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Sharein Farag-El Maasah

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P2860

Effect of polymorphism in the human glutathione S-transferase A1 promoter on hepatic GSTA1 and GSTA2 expression

Up-regulation of glutathione S-transferase activity in enterocytes of young children

Glutathione S-transferase activity influences busulfan pharmacokinetics in patients with beta thalassemia major undergoing bone marrow transplantation.

Plasma concentration monitoring of busulfan: does it improve clinical outcome?

Predicting drug response and toxicity based on gene polymorphisms.

Venoocclusive disease of the liver following bone marrow transplantation.

Busulfan systemic exposure relative to regimen-related toxicity and acute graft-versus-host disease: defining a therapeutic window for i.v. BuCy2 in chronic myelogenous leukemia.

An evaluation of engraftment, toxicity and busulfan concentration in children receiving bone marrow transplantation for leukemia or genetic disease.

Pharmacokinetics of intravenous busulfan in children prior to stem cell transplantation

Busulfan conjugation by glutathione S-transferases alpha, mu, and pi.

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1052-1062

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10.1177/0091270008321940

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9

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48

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2008-07-17T00:00:00Z

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51410223

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18635758

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3204946

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